| Protein: | lis-1 |
| Organism: | Caenorhabditis elegans |
| Length: | 404 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lis-1.
| Description | E-value | Query Range |
Subject Range |
|
|
482.0 | [0..2] | [403..1198] |
|
Region A: Residues: [1-404] |
1 11 21 31 41 51
| | | | | |
1 MSLSERQKEE INRAIAEYMQ NNGYSESFSV FLKESSLSEN DIKPLGGILE KKWTTVLRLQ 60
61 RKVNDLESKL QESQREINHG APTRDKRQAA DWIPRPPETQ KLTGHRLPIT RVIFHPLWTI 120
121 MASCSEDATI KVWDYETGQL ERTLKGHTDA VNDIAIDAAG KQLVSCSSDL SIKLWDFGQT 180
181 YDCLKSLKGH EHTVSSVTFL PTGDFVLSAS RDHTIKQWDI STGYCVYTFR GHNDWVRMIR 240
241 ISNDGTLFAS ASLDQTVTVW SFATKSAKLV LRDHEHAVEC VEWAPDTAYT NVTGQQPEGN 300
301 STHILFSGSR DRSIKAWNIN TGDVLFTLLA HENWVRGLAF HPKGKYLISV ADDKTLRVWE 360
361 LSAQRCMKAI EAHEHFVSTV AFHQTSPFVI TGSVDMSCKV WECR
|
| Detection Method: |  |
| Confidence: | 97.221849 |
| Match: | 1vyhC |
| Description: | PAF-AH Holoenzyme: Lis1/Alfa2 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| dynactin binding | 7.11157019623125 | bayes_pls_golite062009 |
| 6.67009948605948 | bayes_pls_golite062009 | |
| dynein heavy chain binding | 6.59987903164261 | bayes_pls_golite062009 |
| snoRNA binding | 5.79753675747903 | bayes_pls_golite062009 |
| structural molecule activity | 5.05435272846365 | bayes_pls_golite062009 |
| histone methyltransferase activity (H3-K4 specific) | 4.71992275913384 | bayes_pls_golite062009 |
| myosin heavy chain kinase activity | 4.33124151198369 | bayes_pls_golite062009 |
| GTPase activity | 4.02994814377904 | bayes_pls_golite062009 |
| actin binding | 3.86142918698875 | bayes_pls_golite062009 |
| RNA binding | 3.77273677738815 | bayes_pls_golite062009 |
| myosin II binding | 3.56132510021228 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 3.1056443224755 | bayes_pls_golite062009 |
| tubulin binding | 2.76945430061825 | bayes_pls_golite062009 |
| microtubule binding | 2.72684103222924 | bayes_pls_golite062009 |
| dynein binding | 2.54821997913979 | bayes_pls_golite062009 |
| binding | 2.42570478946173 | bayes_pls_golite062009 |
| transcription regulator activity | 2.3610959773142 | bayes_pls_golite062009 |
| nucleic acid binding | 2.30918780727915 | bayes_pls_golite062009 |
| transcription repressor activity | 2.29049708962212 | bayes_pls_golite062009 |
| protein binding | 2.26925404328312 | bayes_pls_golite062009 |
| S-adenosylmethionine-dependent methyltransferase activity | 2.18628561734369 | bayes_pls_golite062009 |
| G-protein-coupled receptor binding | 2.10926890165617 | bayes_pls_golite062009 |
| unfolded protein binding | 2.07597866771866 | bayes_pls_golite062009 |
| actin filament binding | 2.0735069176589 | bayes_pls_golite062009 |
| histone methyltransferase activity | 1.85632145559025 | bayes_pls_golite062009 |
| DNA binding | 1.71685536470455 | bayes_pls_golite062009 |
| telomerase activity | 1.44665328127499 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.41752877005447 | bayes_pls_golite062009 |
| platelet-activating factor acetyltransferase activity | 1.36229564654648 | bayes_pls_golite062009 |
| protein methyltransferase activity | 1.35170368882651 | bayes_pls_golite062009 |
| transporter activity | 1.21549336905926 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.21305848427711 | bayes_pls_golite062009 |
| protein-lysine N-methyltransferase activity | 1.15313682561559 | bayes_pls_golite062009 |
| histone-lysine N-methyltransferase activity | 1.15313682561559 | bayes_pls_golite062009 |
| lysine N-methyltransferase activity | 1.15313682561559 | bayes_pls_golite062009 |
| receptor activity | 1.12819778129653 | bayes_pls_golite062009 |
| RNA-directed DNA polymerase activity | 1.10560669001943 | bayes_pls_golite062009 |
| transcription factor activity | 1.08768505897883 | bayes_pls_golite062009 |
| mRNA binding | 1.05053985350578 | bayes_pls_golite062009 |
| microtubule plus-end binding | 1.01166033978052 | bayes_pls_golite062009 |
| myosin binding | 0.989691178611801 | bayes_pls_golite062009 |
| molecular transducer activity | 0.974380908248463 | bayes_pls_golite062009 |
| signal transducer activity | 0.974380908248463 | bayes_pls_golite062009 |
| protein transporter activity | 0.964340340346761 | bayes_pls_golite062009 |
| type 1 angiotensin receptor binding | 0.920323565472959 | bayes_pls_golite062009 |
| angiotensin receptor binding | 0.920323565472959 | bayes_pls_golite062009 |
| kinase activity | 0.807669232329985 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.805273887494167 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.734793983890004 | bayes_pls_golite062009 |
| dynein intermediate chain binding | 0.707581908546932 | bayes_pls_golite062009 |
| histone binding | 0.685319917508843 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.676924760416604 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.634547834947756 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 0.625780732991652 | bayes_pls_golite062009 |
| protein kinase activity | 0.544118712921054 | bayes_pls_golite062009 |
| transcription factor binding | 0.489473003915035 | bayes_pls_golite062009 |
| insulin receptor binding | 0.43316396073854 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.30761651528651 | bayes_pls_golite062009 |
| DNA helicase activity | 0.220747580531792 | bayes_pls_golite062009 |
| ligase activity | 0.20682813699621 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.161639372576406 | bayes_pls_golite062009 |
| chromatin binding | 0.151977098745772 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.118975415284669 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.0803897416817422 | bayes_pls_golite062009 |
| receptor binding | 0.0390635451962911 | bayes_pls_golite062009 |
| kinase binding | 0.0366162235750993 | bayes_pls_golite062009 |
| protein kinase binding | 0.00858004043229577 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.00585398682921312 | bayes_pls_golite062009 |
| N-methyltransferase activity | 0.00335766408304172 | bayes_pls_golite062009 |
