YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: pab-1
Organism: Caenorhabditis elegans
Length: 646 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pab-1.

Description E-value Query
Range
Subject
Range
gi|73976793 - gi|73976793|ref|XP_857617.1| PREDICTED: similar to poly(A) binding protein, cytoplasmic 4 isoform 1 ...
548.0 [0..23] [646..2]

Back

Predicted Domain #1
Region A:
Residues: [1-211]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEMNVAAPAA AVAGAAAPQP GQNQTGSSYT MASLYVGDLH PDVNESILFE KFSAAGPVLS  60
   61 IRVCRDNATR LSLGYAYVNF QQPADAERAM DTMNFEALHG KPMRIMWSQR DPAMRRSGAG 120
  121 NIFIKNLDKV IDNKSIYDTF SLFGNILSCK VAIDEDGFSK GYGFVHFETE EAAQNAIQKV 180
  181 NGMLLAGKKV FVGKFQPRAQ RNRELGETAK Q

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 58.221849
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
snRNA binding 4.06596327298973 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
U1 snRNA binding 3.02511982045347 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
transcription regulator activity 2.18211199677674 bayes_pls_golite062009
DNA binding 1.98418556946403 bayes_pls_golite062009
structural molecule activity 1.56454315220334 bayes_pls_golite062009
U2 snRNA binding 1.34078165372485 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription factor activity 1.07843408116687 bayes_pls_golite062009
mRNA 3'-UTR binding 0.824614388276642 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [212-307]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FTNVYVKNFG DHYNKETLEK LFAKFGNITS CEVMTVEGKS KGFGFVAFAN PEEAETAVQA  60
   61 LHDSTIEGTD LKLHVCRAQK KSERHAELKK KHEQHK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.522879
Match: 2disA
Description: No description for 2disA was found.

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 4.92126426323641 bayes_pls_golite062009
snRNA binding 4.06596327298973 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
U1 snRNA binding 3.02511982045347 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
transcription regulator activity 2.18211199677674 bayes_pls_golite062009
DNA binding 1.98418556946403 bayes_pls_golite062009
structural molecule activity 1.56454315220334 bayes_pls_golite062009
U2 snRNA binding 1.34078165372485 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription factor activity 1.07843408116687 bayes_pls_golite062009
mRNA 3'-UTR binding 0.824614388276642 bayes_pls_golite062009
sequence-specific DNA binding 0.383589644462932 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [308-394]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AERMQKYQGV NLYVKNLDET VDDDGLKKQF ESYGNITSAK VMTDENGRSK GFGFVCFEKP  60
   61 EEATSAVTEM NSKMVCSKPL YVAIAQR

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.41
Match: 2f3jA
Description: No description for 2f3jA was found.

Predicted Domain #4
Region A:
Residues: [395-504]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEDRRAQLAS QYMQRLASMR MHGNVPGAAM YNPTQPGPGY YVANPMQQQR NFAGGQQMVR  60
   61 PGGRWGMQNQ YPVQNQYMMA QGPGVYQNRM GRPQNQQGGP RGPPQQYNQV 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [505-646]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQGGVRMQGP PRTQNPGVQQ QNVPRPPQQQ QQQRPAPTGP KAPPQPYQAY QQRPQGIVIG  60
   61 GQEPLTSAML AAAAPQEQKQ LLGERIYALI EKLYPGHKDA GKITGMMLEI DNSELIMMLQ 120
  121 DSELFRSKVD EAASVLVSAQ KQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.39794
Match: 1g9lA
Description: poly(A) binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 5.69788763665792 bayes_pls_golite062009
mRNA binding 5.31297072316889 bayes_pls_golite062009
single-stranded RNA binding 4.51056428709072 bayes_pls_golite062009
nucleic acid binding 3.78909647605682 bayes_pls_golite062009
eukaryotic initiation factor 4G binding 3.4111148675327 bayes_pls_golite062009
binding 2.76167454154417 bayes_pls_golite062009
poly(A) RNA binding 2.66269581586161 bayes_pls_golite062009
poly-purine tract binding 2.20136693536924 bayes_pls_golite062009
ubiquitin-protein ligase activity 1.19350242454642 bayes_pls_golite062009
small conjugating protein ligase activity 1.14692713780316 bayes_pls_golite062009
protein binding 0.856075580719879 bayes_pls_golite062009
catalytic activity 0.287695754348243 bayes_pls_golite062009
acid-amino acid ligase activity 0.223805219849164 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle