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View Structure Prediction Details

Protein: tag-165
Organism: Caenorhabditis elegans
Length: 682 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tag-165.

Description E-value Query
Range		 Subject
Range
gi|114598948, gi... - gi|114598948|ref|XP_001145174.1| PREDICTED: methionine synthase reductase isoform 3 [Pan troglodytes...
 444.0 [0..1] [681..1]

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Predicted Domain #1
Region A:
Residues: [1-71] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDFLIAFGS QTGQAETIAK SLKEKAELIG LTPRLHALDE NEKKFNLNEE KLCAIVVSST  60
   61 GDGDAPDNCA R

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.0
Match: 1fx1A
Description: A CRYSTALLOGRAPHIC STRUCTURAL STUDY OF THE OXIDATION STATES OF DESULFOVIBRIO VULGARIS FLAVODOXIN
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [72-682] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FVRRINRNSL ENEYLKNLDY VLLGLGDSNY SSYQTIPRKI DKQLTALGAN RLFDRAEADD  60
   61 QVGLELEVEP WIEKFFATLA SRFDISADKM NAITESSNLK LNQVKTEEEK KALLQKRIED 120
  121 EESDDEGRGR VIGIDMLIPE HYDYPEISLL KGSQTLSNDE NLRVPIAPQP FIVSSVSNRK 180
  181 LPEDTKLEWQ NLCKMPGVVT KPFEVLVVSA EFVTDPFSKK IKTKRMITVD FGDHAAELQY 240
  241 EPGDAIYFCV PNPALEVNFI LKRCGVLDIA DQQCELSINP KTEKINAQIP GHVHKITTLR 300
  301 HMFTTCLDIR RAPGRPLIRV LAESTSDPNE KRRLLELCSA QGMKDFTDFV RTPGLSLADM 360
  361 LFAFPNVKPP VDRLIELLPR LIPRPYSMSS YENRKARLIY SEMEFPATDG RRHSRKGLAT 420
  421 DWLNSLRIGD KVQVLGKEPA RFRLPPLGMT KNSAGKLPLL MVGPGTGVSV FLSFLHFLRK 480
  481 LKQDSPSDFV DVPRVLFFGC RDSSVDAIYM SELEMFVSEG ILTDLIICES EQKGERVQDG 540
  541 LRKYLDKVLP FLTASTESKI FICGDAKGMS KDVWQCFSDI VASDQGIPDL EAKKKLMDLK 600
  601 KSDQYIEDVW G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 111.0
Match: 1amoA
Description: NADPH-cytochrome p450 reductase; NADPH-cytochrome p450 reductase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on NADH or NADPH 3.51215695612257 bayes_pls_golite062009
arginine binding 3.31453699236145 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor 3.111558299994 bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity 3.08675205479908 bayes_pls_golite062009
oxidoreductase activity 3.02740987944465 bayes_pls_golite062009
tetrahydrobiopterin binding 3.017442325411 bayes_pls_golite062009
NADH dehydrogenase activity 2.33166813913888 bayes_pls_golite062009
NADH dehydrogenase (quinone) activity 2.25895189750633 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 2.0960591627763 bayes_pls_golite062009
FAD binding 2.07600122867642 bayes_pls_golite062009
transcription regulator activity 2.07119387257991 bayes_pls_golite062009
coenzyme binding 1.94345417147733 bayes_pls_golite062009
binding 1.76189957257133 bayes_pls_golite062009
nitric-oxide synthase activity 1.73361245661515 bayes_pls_golite062009
cytochrome-b5 reductase activity 1.5685421124725 bayes_pls_golite062009
catalytic activity 1.45374095556065 bayes_pls_golite062009
phosphoric diester hydrolase activity 1.30413377266725 bayes_pls_golite062009
NADP or NADPH binding 1.18833847639357 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen 0.878188072733981 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 0.73388842564789 bayes_pls_golite062009
transferase activity 0.708491789248912 bayes_pls_golite062009
FMN binding 0.649158247260553 bayes_pls_golite062009
NAD(P)H oxidase activity 0.46219666758416 bayes_pls_golite062009
riboflavin synthase activity 0.380537461428523 bayes_pls_golite062009
protein binding 0.244726474314668 bayes_pls_golite062009
cofactor binding 0.205324283520452 bayes_pls_golite062009
transcription factor binding 0.065157440608373 bayes_pls_golite062009
cytoskeletal protein binding 0.0373671593900911 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle