YRC Public Data Repository - Protein Structure Prediction

Protein:	fet5
Organism:	Schizosaccharomyces pombe
Length:	276 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for fet5.

Description	E-value	Query Range	Subject Range
GPN3_USTMA, FET5... - GPN-loop GTPase 3 homolog UM01243 OS=Ustilago maydis GN=UM01243 PE=3 SV=1, Transcription factor FET5... GPN3_USTMA - GPN-loop GTPase 3 OS=Ustilago maydis (strain 521 / FGSC 9021) GN=UMAG_01243 PE=3 SV=1	217.0	[0..1]	[271..1]
gi\|114646897 - gi\|114646897\|ref\|XP_001142177.1\| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes]	215.0	[0..1]	[270..174]
GPN3_ASHGO - GPN-loop GTPase 3 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) GN=A... FET5_ASHGO, GPN3... - GPN-loop GTPase 3 homolog AGL117C OS=Ashbya gossypii GN=AGL117C PE=3 SV=1, Transcription factor FET5...	214.0	[0..1]	[272..1]
FET5_CRYNE, GPN3... - GPN-loop GTPase 3 homolog CNB04680/CNBB1090 OS=Cryptococcus neoformans GN=CNB04680 PE=3 SV=1, Transc... GPN3_CRYNB - GPN-loop GTPase 3 OS=Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) GN=CNBB1090... GPN3_CRYNJ - GPN-loop GTPase 3 OS=Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565...	213.0	[0..2]	[271..1]
gi\|50307779, gi\|... - gi\|50307779\|ref\|XP_453883.1\| unnamed protein product [Kluyveromyces lactis], gi\|49643017\|emb\|CAH0097... gi\|49643017 - gi\|49643017\|emb\|CAH00979.1\| KLLA0D18557p [Kluyveromyces lactis]	212.0	[0..1]	[272..31]
gi\|68481329, gi\|... - gi\|68481329\|ref\|XP_715439.1\| conserved hypothetical ATP-binding protein [Candida albicans SC5314], g... orf19.3130, orf1... - orf19.3130 CGDID:CAL0002280 Assembly 19, Contig19-10166 (89673, 88678) CDS, reverse complemented, tr...	206.0	[0..1]	[273..59]
FET5_CANGA, GPN3... - GPN-loop GTPase 3 homolog CAGL0G08294g OS=Candida glabrata GN=CAGL0G08294g PE=3 SV=1, Transcription ... GPN3_CANGA - GPN-loop GTPase 3 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65...	202.0	[0..1]	[272..1]
gi\|207342912 - gi\|207342912\|gb\|EDZ70535.1\| YLR243Wp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190405305 - gi\|190405305\|gb\|EDV08572.1\| hypothetical protein SCRG_04196 [Saccharomyces cerevisiae RM11-1a] GPN3_YEAST - GPN-loop GTPase 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GPN3 PE=1 SV=1 YLR243W - Putative protein of unknown function; YLR243W is an essential gene	199.0	[0..1]	[266..1]
gi\|76611336 - gi\|76611336\|ref\|XP_611547.2\| PREDICTED: similar to CG10222-PA [Bos taurus]	197.0	[0..8]	[268..161]
gi\|215769078, gi... - gi\|222625678\|gb\|EEE59810.1\| hypothetical protein OsJ_12343 [Oryza sativa Japonica Group], gi\|2157690... gi\|218193640 - gi\|218193640\|gb\|EEC76067.1\| hypothetical protein OsI_13279 [Oryza sativa Indica Group]	197.0	[0..2]	[271..1]

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Predicted Domain #1

Region A:
Residues: [1-276]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKVAAFVCG VASSGKSTFC GALMSYMKSV GRSCHLVNLD PAAENFEWEP TVDIRDLISI  60
   61 DDVMEELDYG PNGGLIYCFE FLMENLDWLN EEIGDYDEDY LIFDMPGQIE LYTHVPILPA 120
  121 LIRHLQVTLN FRPCAVYLLE SQFLVDRTKF FAGVLSAMSA MVMMEVPHIN LLSKMDLLKD 180
  181 NNNITKAELK RFLNTDPLLL TGEINETTNP KFHELNRCIV QLIDDFNMVN FLPLESGNEE 240
  241 SVSRVLSYID DATQWYEDQE PKDPDRFEAD DLEDDE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	27.522879
Match:	1yr6A
Description:	PAB0955 crystal structure : a GTPase in Apo form from Pyrococcus abyssi
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleoside-triphosphatase activity	2.95079405147356	bayes_pls_golite062009
pyrophosphatase activity	2.87427509025394	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.85499564954033	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.85178667290149	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.82708337557815	bayes_pls_golite062009
ion transmembrane transporter activity	2.73258998901465	bayes_pls_golite062009
transporter activity	2.58140740499725	bayes_pls_golite062009
cation transmembrane transporter activity	2.55141814687566	bayes_pls_golite062009
binding	2.44689197844883	bayes_pls_golite062009
transmembrane transporter activity	2.39695871109024	bayes_pls_golite062009
ATPase activity	2.39535714892224	bayes_pls_golite062009
ATPase activity, coupled	2.18396165590908	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	1.93945622138684	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	1.89410061122763	bayes_pls_golite062009
metal ion transmembrane transporter activity	1.63387464349089	bayes_pls_golite062009
hydrolase activity	1.57549510726226	bayes_pls_golite062009
substrate-specific transporter activity	1.29730375126024	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	1.28706187447607	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	1.14579511548336	bayes_pls_golite062009
purine nucleotide binding	0.929901285538132	bayes_pls_golite062009
nucleotide binding	0.922442819194247	bayes_pls_golite062009
purine ribonucleotide binding	0.920987930180051	bayes_pls_golite062009
ribonucleotide binding	0.920926158369519	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	0.699203719711999	bayes_pls_golite062009
nucleic acid binding	0.646641337908559	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	0.600852003734846	bayes_pls_golite062009
active transmembrane transporter activity	0.434775387083003	bayes_pls_golite062009
ATP binding	0.41092997612902	bayes_pls_golite062009
adenyl ribonucleotide binding	0.385813421701492	bayes_pls_golite062009
adenyl nucleotide binding	0.377870145186619	bayes_pls_golite062009
DNA binding	0.334939970943935	bayes_pls_golite062009
primary active transmembrane transporter activity	0.294474570607914	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.282352478532746	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	0.220608508617331	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	0.219533217661421	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	0.219157471322311	bayes_pls_golite062009
cation channel activity	0.192467810264152	bayes_pls_golite062009
iron ion transmembrane transporter activity	0.160869143323446	bayes_pls_golite062009
transcription regulator activity	0.147805393867298	bayes_pls_golite062009
protein binding	0.071010918255742	bayes_pls_golite062009
motor activity	0.0492636236578701	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: