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View Structure Prediction Details

Protein: SPBC29A3.01
Organism: Schizosaccharomyces pombe
Length: 904 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC29A3.01.

Description E-value Query
Range
Subject
Range
gi|29374937, gi|... - gi|29374937|ref|NP_814090.1| copper-translocating P-type ATPase [Enterococcus faecalis V583], gi|293...
681.0 [0..1] [854..1]
gi|145408869, gi... - gi|82499630|ref|ZP_00885070.1| ATPase, E1-E2 type:Copper ion-binding:Copper-translocating P-type ATP...
674.0 [0..1] [856..1]
gi|66780411, gi|... - gi|94972060|ref|YP_594100.1| heavy metal translocating P-type ATPase [Deinococcus geothermalis DSM 1...
666.0 [0..3] [862..4]
gi|56419437, gi|... - gi|56419437|ref|YP_146755.1| heavy metal-transporting ATPase [Geobacillus kaustophilus HTA426], gi|5...
663.0 [0..2] [853..5]
gi|20808818 - gi|20808818|ref|NP_623989.1| Cation transport ATPase [Thermoanaerobacter tengcongensis MB4]
gi|20517469, gi|... - gi|20808818|ref|NP_623989.1| cation transport ATPase [Thermoanaerobacter tengcongensis MB4], gi|2051...
657.0 [0..2] [853..3]
gi|242258479, gi... - gi|242258479|ref|ZP_04803277.1| copper-translocating P-type ATPase [Thermoanaerobacter sp. X513], gi...
gi|241903577, gi... - gi|241903577|ref|ZP_04788299.1| copper-translocating P-type ATPase [Thermoanaerobacter brockii subsp...
gi|76588523, gi|... - gi|76796112|ref|ZP_00778480.1| ATPase, E1-E2 type:Copper ion-binding:Copper-translocating P-type ATP...
gi|114844533, gi... - gi|167039429|ref|YP_001662414.1| copper-translocating P-type ATPase [Thermoanaerobacter sp. X514], g...
656.0 [0..2] [853..3]
gi|89897256, gi|... - gi|89897256|ref|YP_520743.1| hypothetical protein DSY4510 [Desulfitobacterium hafniense Y51], gi|893...
653.0 [0..1] [854..1]
gi|89095980, gi|... - gi|89095980|ref|ZP_01168873.1| YvgX [Bacillus sp. NRRL B-14911], gi|89088834|gb|EAR67942.1| YvgX [Ba...
652.0 [0..2] [853..6]
gi|15613120, gi|... - gi|15613120|ref|NP_241423.1| copper-transporting ATPase [Bacillus halodurans C-125], gi|10173170|dbj...
gi|25290739 - pir||E83719 copper-transporting ATPase BH0557 [imported] - Bacillus halodurans (strain C-125)
652.0 [0..2] [855..5]

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Predicted Domain #1
Region A:
Residues: [1-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYTTTLSVQG MTCTSCVASI QSMLEGVEGI EQFTISLLLE RAIAVHDPSI ISPDQIAEKI  60
   61 EDCGFDASVI SSTEGEHGVM ANYLLLSPMQ AEQWTKVHNH INELQGVLSV NCSSSPDAAI 120
  121 RVIYDSEITG PRSIMKEILS MGVKCTFQPV DSSTSRILSL 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.522879
Match: 1p6tA
Description: Structure characterization of the water soluble region of P-type ATPase CopA from Bacillus subtilis
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
copper chaperone activity 9.82063669832995 bayes_pls_golite062009
copper-dependent protein binding 9.4886676850819 bayes_pls_golite062009
metallochaperone activity 8.74818422646376 bayes_pls_golite062009
superoxide dismutase copper chaperone activity 7.67724993505658 bayes_pls_golite062009
copper ion transmembrane transporter activity 6.91184156399207 bayes_pls_golite062009
copper ion binding 5.41725082570189 bayes_pls_golite062009
metal ion transmembrane transporter activity 5.4007166857771 bayes_pls_golite062009
copper-exporting ATPase activity 5.04749761961029 bayes_pls_golite062009
copper-transporting ATPase activity 5.03252922496602 bayes_pls_golite062009
transition metal ion transmembrane transporter activity 4.79570221435856 bayes_pls_golite062009
cation transmembrane transporter activity 4.61622753861072 bayes_pls_golite062009
ion transmembrane transporter activity 4.52484959112186 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 4.12792340516867 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 4.10264569844449 bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity 3.70964017127302 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 3.27250923701445 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions 2.98847682261773 bayes_pls_golite062009
metal ion binding 2.69806984896689 bayes_pls_golite062009
cation binding 2.69806984896689 bayes_pls_golite062009
ion binding 2.69078950610234 bayes_pls_golite062009
transition metal ion binding 2.52520930681159 bayes_pls_golite062009
transporter activity 2.43435890488191 bayes_pls_golite062009
transmembrane transporter activity 2.32163502360862 bayes_pls_golite062009
binding 2.31155280022787 bayes_pls_golite062009
substrate-specific transporter activity 2.28845421748925 bayes_pls_golite062009
primary active transmembrane transporter activity 1.62116507842838 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 1.61680623728503 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 1.59572740343301 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 1.5925429451548 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 1.59219836319916 bayes_pls_golite062009
active transmembrane transporter activity 1.53883152283038 bayes_pls_golite062009
hydrolase activity 1.26149508477113 bayes_pls_golite062009
ATPase activity 1.12732384636594 bayes_pls_golite062009
nucleoside-triphosphatase activity 1.1123150216263 bayes_pls_golite062009
pyrophosphatase activity 1.04872000948037 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.03270166246194 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.02977205960797 bayes_pls_golite062009
ATPase activity, coupled 1.02520458852568 bayes_pls_golite062009
protein binding 0.889287086236279 bayes_pls_golite062009
cation-transporting ATPase activity 0.75722873989123 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [161-904]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRGSQIRVWK IRFIISISFS LAVMFLPQIF DSCDSMRAAF LVPHYFGICA GHIISLVLSL  60
   61 PVQFGVGRVY YSAAYHALKR GTANMDVLVS LGSTVAFAAS IFFMILYSAR HADNPAPIFF 120
  121 DTADMLLTFV TLGRYLESKA KGSTSAALSQ LLSLAPSSAT IIEDNEQIEI LADLIERGDL 180
  181 ILVKPGEIIP VDGTVVEGSS YVDESSVSGE PVPVHKTIDD ELLSGTANGN GRLLVKATKS 240
  241 PRESQLAVIV DLVQRAQISH APIQQFADRV AGIFVPVIVA LSISTFTFWF LFTKYSSKYP 300
  301 SVFDDPMGKF AVCLKLTISV VVVACPCALG LSTPTAVMVG TGVGALNGII IKGGEILERL 360
  361 NQVDTVVFDK TGTLTVGKLS VTDISIVDNL EELLDIPKNI FWAFVKASES SSEHPIGKAI 420
  421 TEKASEFTDV SEIGIESFNA VPGEGVDVVL RWKERTFHAL LGNSLLLEHN NVSIPDDFDS 480
  481 KLKLSSSSGL TCVRIAIDGQ FVGFLGCMDQ VRPDSYQTVS ALKQLGKKVC LLTGDQKATA 540
  541 RRVAQGLEID FSDVYAEAVP SQKAEIIQKL KDQKHCVAMV GDGINDSPSL VLADVGIAPI 600
  601 NGSGIALESA DVILVRKGVL LDTAVSFDLS RVIVKRIKMN LVWACIYNFV MIPIAMGFFL 660
  661 PWGIYLNPMW ASAAMMFSSL SVLASSLLLR RWKKPKSLIF SEADDVETES STNSSVLQKV 720
  721 YTATRSIFGR NKSSNKYQPV ANEV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 108.0
Match: 1mhsA
Description: Proton ATPase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle