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View Structure Prediction Details

Protein: SPAC644.11c
Organism: Schizosaccharomyces pombe
Length: 425 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC644.11c.

Description E-value Query
Range
Subject
Range
gi|73668585, gi|... - gi|73668585|ref|YP_304600.1| sensory transduction histidine kinase [Methanosarcina barkeri str. Fusa...
246.0 [0..1] [423..347]
gi|21229201, gi|... - gi|21229201|ref|NP_635123.1| two component system histidine kinase [Methanosarcina mazei Go1], gi|20...
245.0 [0..40] [417..339]
gi|19918507, gi|... - gi|20093164|ref|NP_619239.1| sensory transduction histidine kinase [Methanosarcina acetivorans C2A],...
244.0 [0..1] [423..331]
gi|91203275 - gi|91203275|emb|CAJ72914.1| conserved hypothetical protein [Candidatus Kuenenia stuttgartiensis]
244.0 [0..126] [420..266]
gi|68186676, gi|... - gi|91772668|ref|YP_565360.1| PAS/PAC sensor signal transduction histidine kinase [Methanococcoides b...
243.0 [0..119] [415..181]
gi|125715042, gi... - gi|67876335|ref|ZP_00505222.1| PAS [Clostridium thermocellum ATCC 27405], gi|67850119|gb|EAM45704.1|...
242.0 [0..17] [418..217]
gi|150017029, gi... - gi|82745764|ref|ZP_00908274.1| Response regulator receiver:ATP-binding region, ATPase-like:Histidine...
241.0 [0..93] [425..376]
gi|78486517, gi|... - gi|78486517|ref|YP_392442.1| PAS/PAC sensor hybrid histidine kinase [Thiomicrospira crunogena XCL-2]...
241.0 [0..30] [414..777]

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Predicted Domain #1
Region A:
Residues: [1-425]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVLGKTLQE KVNLLAQYPQ TGLSLKQLVY FGKNPTPGTL FRAGLFLRDE LPIRLARRIQ  60
   61 DLQNLSPMLR SMKRISSVKA AYGRSMEEII ELKGVELPKC LPKHARYHNA PKWRSSLMDS 120
  121 EILHNPSLAN THLDSSKGRY FETDFSDQDN GVDCNWPESL LKFNSNFAYL LNTIRTRHDN 180
  181 VAVEIALDIQ EYRRKTNQID NSIQIFLDRF YMSRIGIRML LGQYIALVSE PPRENYVGVI 240
  241 STRANIYQII EGAAENAKYI CRLAYGLFEA PEIQIICDPS LEMMYVESHL NHAVFEILKN 300
  301 SLRATVEFHG VDSDFFPPIK VIVAKGQEDI TIKISDEGGG ISRRNIPLVW SYMFTTASPT 360
  361 LTDDPHDIVS ANSTTPMAGF GFGLPLARLY TRYFGGDLEL ISMEGYGTDV YIHLNRLCES 420
  421 AEPLQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.30103
Match: 1y8nA
Description: Crystal structure of the PDK3-L2 complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein kinase activity 5.01870623976931 bayes_pls_golite062009
kinase activity 4.85138131686277 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 4.81481543379001 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.45079252748792 bayes_pls_golite062009
transferase activity 3.26506680041137 bayes_pls_golite062009
signal transducer activity 2.6840711108909 bayes_pls_golite062009
molecular transducer activity 2.6840711108909 bayes_pls_golite062009
[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity 2.36085090526335 bayes_pls_golite062009
catalytic activity 2.10890475146569 bayes_pls_golite062009
DNA topoisomerase (ATP-hydrolyzing) activity 0.79782232607661 bayes_pls_golite062009
protein serine/threonine kinase activity 0.645369132696288 bayes_pls_golite062009
transcription regulator activity 0.487571066153031 bayes_pls_golite062009
binding 0.479605157919228 bayes_pls_golite062009
DNA topoisomerase activity 0.46463788040368 bayes_pls_golite062009
nucleic acid binding 0.452314252314567 bayes_pls_golite062009
DNA binding 0.363457731788666 bayes_pls_golite062009
ATP binding 0.046931113566547 bayes_pls_golite062009
adenyl nucleotide binding 0.0466395564910416 bayes_pls_golite062009
adenyl ribonucleotide binding 0.0158273741152592 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle