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View Structure Prediction Details

Protein: SPACUNK4.16c
Organism: Schizosaccharomyces pombe
Length: 944 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPACUNK4.16c.

Description E-value Query
Range
Subject
Range
gi|42552929, gi|... - gi|46122639|ref|XP_385873.1| hypothetical protein FG05697.1 [Gibberella zeae PH-1], gi|42552929|gb|E...
527.0 [0..4] [943..3]
TPS7_ARATH - Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 7 OS=Arabidopsis thaliana GN=TPS7 PE...
520.0 [0..103] [944..1]
gi|60265773, gi|... - gi|60265773|gb|AAX16015.1| trehalose-6-phosphate synthase [Ginkgo biloba], gi|60265771|gb|AAX16014.1...
520.0 [0..103] [944..1]
gi|28926747, gi|... - gi|32408985|ref|XP_324973.1| hypothetical protein [Neurospora crassa], gi|28926747|gb|EAA35713.1| hy...
gi|85115848 - gi|85115848|ref|XP_964949.1| hypothetical protein [Neurospora crassa OR74A]
517.0 [0..4] [941..3]
gi|19568935 - gi|19568935|gb|AAL91978.1|AF483209_1 putative trehalose synthase [Solanum tuberosum]
506.0 [0..103] [944..1]
gi|215695376, gi... - gi|57899511|dbj|BAD86973.1| putative trehalose-6-phosphate synthase/phosphatase [Oryza sativa Japoni...
504.0 [0..103] [944..1]

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Predicted Domain #1
Region A:
Residues: [1-186]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRILIAHLF LPSSVGFSFD TVPHDEVGSK FMQKEESKDW IADTPLDESA IVSEEESDDD  60
   61 SLLSDLPEEI DSTNAQSNIA TPSPGTVAAA ISGIQPPPKT PSSDSPSLEN SLSNLNDLFK 120
  121 SRGRHMAFSK NDGTNLSLPP SRHQSPPPSS VLASQRHHRR HDSELEEFAR RASRSLSFSM 180
  181 NGTPQR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [187-665]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RMTFDAEAWK NVIFKIKPSS FGNASFYNAI SAATRSKQFD DHLFVGTCGI PTDSLPDSLK  60
   61 ERISHDYITE HSSLVVYPTD TDFVGHYNHY CKNILWPTFH YQIPDNPKSK AYEDHSWANY 120
  121 VKVNKAFADT IVDNYEQDDM IWINDYHLLL VPEMVRERLP RAKIGFFLHI PFPSSEVFRC 180
  181 LATRQEILKG MLGANILGFQ IPEFAYHFLQ TCSRLVNIDI RKNGVVSFEN RQIDVIALPI 240
  241 SIDPGFIDRC LASPPVEHWA KVLQDRFRGK HIILSHDKLD PIRGLRSKLI SFERFLQKYP 300
  301 EYRENTILLQ VAPESLQDSE HLPHISDIVT RINSAYSNIA SRHVPVILLR QKLGYAQFLA 360
  361 LMMISDALID NSLREGISLT SHQFIYVQRK RHRPLILSEF VGSASILNDN AIIVNPWDYS 420
  421 KTAEAFRTAL TMSEEECQKR NKAMCNLILR HDAASWAVTF QSLIKESWKE QIDMQRIPA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 71.0
Match: 1uqtA
Description: Trehalose-6-phosphate from E. coli bound with UDP-2-fluoro glucose.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity 11.2045941324603 bayes_pls_golite062009
glucosyltransferase activity 8.25064561355471 bayes_pls_golite062009
UDP-glucosyltransferase activity 8.0463972704113 bayes_pls_golite062009
trehalose-phosphatase activity 7.58500038184065 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 3.70184884300914 bayes_pls_golite062009
catalytic activity 2.65148466065976 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 2.62403914335522 bayes_pls_golite062009
transferase activity 2.18054407163329 bayes_pls_golite062009
UDP-glycosyltransferase activity 2.13085705769565 bayes_pls_golite062009
UDP-N-acetylglucosamine 2-epimerase activity 1.55280519670033 bayes_pls_golite062009
carbohydrate phosphatase activity 0.78952375993773 bayes_pls_golite062009
glycogen phosphorylase activity 0.607220464589157 bayes_pls_golite062009
binding 0.345236672370351 bayes_pls_golite062009
phosphorylase activity 0.296436712681472 bayes_pls_golite062009
mannosyltransferase activity 0.253888301381021 bayes_pls_golite062009
protein binding 0.198267161626932 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [666-944]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FTAQLIKEPY QNAQKRLILL YFEGTISTWG SQYHNVMTSL QRTINLLNML TSDPKNTVYV  60
   61 FSALSCQELE QLFQRVPKLG IVAENGCFVR SPPKGDATMP VSKKEIAELW KNKVLGTDLT 120
  121 WMKTVSEIFE YYAERTTGAY VENKDATVIL HLREAEDDEA AMWAAKECCE SVNNFNVPCS 180
  181 ATIQNDMVVC RSNKVSKRLA AEDIYSANGG DYDFIFAASN DPDDDTVFSW MKNFKQSKKE 240
  241 VVPFTFSVCV SEHGNSTNAD AESSGVFGFL QALEKVYSA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.0
Match: 1rkqA
Description: Crystal structure of NYSGRC target T1436: A Hypothetical protein yidA.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
trehalose-phosphatase activity 3.78859922218487 bayes_pls_golite062009
transporter activity 2.28749015584769 bayes_pls_golite062009
hydrolase activity 2.23636068759523 bayes_pls_golite062009
transmembrane transporter activity 2.17051010073814 bayes_pls_golite062009
substrate-specific transporter activity 2.14633664297706 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.05684652641195 bayes_pls_golite062009
ion transmembrane transporter activity 2.05060633349756 bayes_pls_golite062009
cation transmembrane transporter activity 1.84740904871745 bayes_pls_golite062009
catalytic activity 1.55296860681783 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions 1.53201151596704 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 1.45647470429539 bayes_pls_golite062009
ATPase activity, coupled 1.44542004757594 bayes_pls_golite062009
nucleoside-triphosphatase activity 1.42792997211574 bayes_pls_golite062009
ATPase activity 1.40341876769691 bayes_pls_golite062009
pyrophosphatase activity 1.352553895791 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 1.33388154652051 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.33292469269496 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.33065047107664 bayes_pls_golite062009
metal ion transmembrane transporter activity 1.31602086166435 bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity 0.28050944646617 bayes_pls_golite062009
active transmembrane transporter activity 0.194344891491143 bayes_pls_golite062009
phosphatase activity 0.159899259988948 bayes_pls_golite062009
cation-transporting ATPase activity 0.15490458026932 bayes_pls_golite062009
nucleic acid binding 0.143980906464589 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.103902756538853 bayes_pls_golite062009
primary active transmembrane transporter activity 0.053543166906854 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.041293091790546 bayes_pls_golite062009
binding 0.0209333912048011 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle