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View Structure Prediction Details

Protein: rpa43
Organism: Schizosaccharomyces pombe
Length: 173 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rpa43.

Description E-value Query
Range
Subject
Range
gi|50728670 - gi|50728670|ref|XP_416229.1| PREDICTED: similar to Polymerase (RNA) III (DNA directed) polypeptide H...
173.0 [0..6] [155..301]
gi|13359203 - gi|13359203|dbj|BAB33335.1| KIAA1665 protein [Homo sapiens]
166.0 [0..6] [155..15]
rpb-7 - status:Partially_confirmed UniProt:Q9N3C9 protein_id:AAF59550.1
164.0 [0..6] [170..25]
gi|38567178 - gi|38567178|emb|CAE76471.1| probable DNA-directed RNA polymerase II chain Rpb7 [Neurospora crassa]
164.0 [0..6] [171..2]
rpb7 - DNA-directed RNA polymerase complex II subunit Rpb7
RPB7_SCHPO - DNA-directed RNA polymerase II subunit rpb7 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G...
164.0 [0..5] [170..2]
gi|114638047 - gi|114638047|ref|XP_001142605.1| PREDICTED: similar to RNA polymerase II subunit hsRPB7 [Pan troglod...
163.0 [0..6] [170..57]
gi|90081264 - gi|90081264|dbj|BAE90112.1| unnamed protein product [Macaca fascicularis]
gi|109105730 - gi|109105730|ref|XP_001116154.1| PREDICTED: similar to polymerase (RNA) II (DNA directed) polypeptid...
163.0 [0..9] [170..54]
gi|157136015, gi... - gi|157136015|ref|XP_001656728.1| DNA-directed RNA polymerase II 19 kDa polypeptide rpb7 [Aedes aegyp...
162.0 [0..6] [170..2]

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Predicted Domain #1
Region A:
Residues: [1-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPDLSLYKQT VDLYLSIAPG HSRDPLNAIQ EHMDSMILSK LPRINGIVLA YDNIRFLEKS  60
   61 AKVMYDSPFS FIWVRVDVLV FSPKKGDCLE GKINLVSPSH IGLLILGIFN ASIPRKSIPK 120
  121 DWIFIEPDTT EEQGRWKTND GNILEPGKDL EFVVDGIQRE AGLTMVQGTL ANS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.045757
Match: 2c35B
Description: Subunits Rpb4 and Rpb7 of human RNA polymerase II
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA polymerase activity 8.99678434167899 bayes_pls_golite062009
DNA-directed RNA polymerase activity 8.99678434167899 bayes_pls_golite062009
nucleotidyltransferase activity 6.44182740737882 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.38397648153969 bayes_pls_golite062009
transferase activity 3.90847350895308 bayes_pls_golite062009
DNA binding 3.47278447192966 bayes_pls_golite062009
binding 2.49444158679862 bayes_pls_golite062009
structural constituent of ribosome 2.13063800565247 bayes_pls_golite062009
transcription regulator activity 2.10110937001387 bayes_pls_golite062009
nucleic acid binding 1.99830040887738 bayes_pls_golite062009
structural molecule activity 1.9177190829469 bayes_pls_golite062009
structure-specific DNA binding 1.81524862921454 bayes_pls_golite062009
single-stranded DNA binding 1.62996999055328 bayes_pls_golite062009
ribonuclease activity 1.19236946227657 bayes_pls_golite062009
catalytic activity 1.02941336036162 bayes_pls_golite062009
transcription factor activity 0.937752547283357 bayes_pls_golite062009
sequence-specific DNA binding 0.76825863122436 bayes_pls_golite062009
nuclease activity 0.57381531077345 bayes_pls_golite062009
translation regulator activity 0.31332179848255 bayes_pls_golite062009
protein binding 0.304236148450282 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.263197317040851 bayes_pls_golite062009
translation initiation factor activity 0.2080607201312 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 0.125256208482441 bayes_pls_golite062009
exoribonuclease activity 0.109774918833391 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle