YRC Public Data Repository - Protein Structure Prediction

Protein:	ccr1
Organism:	Schizosaccharomyces pombe
Length:	678 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ccr1.

Description	E-value	Query Range	Subject Range
gi\|85112967 - gi\|85112967\|ref\|XP_964443.1\| NADPH-cytochrome P450 reductase [Neurospora crassa OR74A] gi\|32419895, gi\|... - gi\|32419895\|ref\|XP_330391.1\| hypothetical protein [Neurospora crassa], gi\|28926225\|gb\|EAA35207.1\| NA...	537.0	[0..1]	[678..4]
gi\|145019585, gi... - gi\|39971603\|ref\|XP_367192.1\| hypothetical protein MGG_07117 [Magnaporthe grisea 70-15], gb\|EAA56762....	535.0	[0..1]	[678..4]
gi\|32562989 - gi\|32562989\|emb\|CAE09055.1\| cytochrome P450 oxidoreductase [Gibberella fujikuroi]	521.0	[0..1]	[675..4]
gi\|62089334 - gi\|62089334\|dbj\|BAD93111.1\| Hypothetical protein DKFZp686G04235 variant [Homo sapiens]	519.0	[0..4]	[678..35]
gi\|49523481 - gi\|49523481\|emb\|CAE76653.1\| NADPH cytochrome P450 oxidoreductase [Botryotinia fuckeliana] gi\|154317749, gi... - gi\|154317749\|ref\|XP_001558194.1\| hypothetical protein BC1G_03226 [Botryotinia fuckeliana B05.10], gi...	519.0	[0..1]	[678..5]
gi\|499862, gi\|19... - gi\|499862\|gb\|AAA85368.1\| NADPH-cytochrome P-450 oxidoreductase, gi\|194018678\|ref\|NP_001123431.1\| P45...	519.0	[0..3]	[678..25]
gi\|109066224 - gi\|109066224\|ref\|XP_001109664.1\| PREDICTED: P450 (cytochrome) oxidoreductase isoform 2 [Macaca mulat...	518.0	[0..4]	[678..29]

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Predicted Domain #1

Region A:
Residues: [1-678]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTYEYVLLV IILILSLCYF IYNNFLNKPK APERRVVATD SIVELMEAEK LTAAVFFGSQ  60
   61 TGTAEDFAYR FSTEAKANFN LTNMVFDLEN YDLTDLDNFD RSKLLVFFLA TYGEGEPTDN 120
  121 AEAFLQLLEG DDTVFSSGKG IEDTPFEGIR YAIFGLGNHT YEYYNAMAKK VDAAMTRLGA 180
  181 TRVGNLGLGD DAAGMLEEDY LQWKDDTLPE IGKLFHLQEV HKEYNPMFEV IEKPEISNTS 240
  241 STVFLGEPSR QQLKGNVASK APRSQANPFF SSPVRSLELF KSGSRNCLHL ELDIADSGMR 300
  301 YQTGDYASIC PMNPSQAVDD LLEVLGLKEK RDTVIIVKPI DTLDKAPVLS PTTYDTVFRY 360
  361 YYEICGIVSR QLLSFIAPFA PTPESKQELE KLGNDYDYFK KNVVDLHLNL AQVLRRVSPD 420
  421 APFTKLPFSM LLENMAHMKP RYYSISSSSV VHPDKVHVTA VVDKKEWTDK NHIFYGLTTN 480
  481 YLLAHCRHMH GEKIPHPNGL EYTLEGPRKN WTGKIPMFVK KSTFRLAPPD VPIIMVGPGT 540
  541 GVAPFRGFVM ERANLASKGV KVAKTLLFYG CQYSDKDFLY KEEWQQYKDV LKDSFELITA 600
  601 FSREQDHKIY VQHRLLEHSD TIAKLVEEGA AFYICGDADH MAKDVVNALA SILTTVDVDG 660
  661 MKAVKALRDD NRFFEDTW

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	141.0
Match:	1amoA
Description:	NADPH-cytochrome p450 reductase; NADPH-cytochrome p450 reductase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
sulfite reductase (NADPH) activity	8.084406223553	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor	4.30314846685644	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	4.19887641848781	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	4.06091555929351	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	3.8525097290463	bayes_pls_golite062009
arginine binding	3.31453699236145	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor	3.111558299994	bayes_pls_golite062009
NADH dehydrogenase activity	3.09973680094998	bayes_pls_golite062009
oxidoreductase activity	3.02740987944465	bayes_pls_golite062009
tetrahydrobiopterin binding	3.017442325411	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	3.01705400717654	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	2.84592668144284	bayes_pls_golite062009
FAD binding	2.07600122867642	bayes_pls_golite062009
transcription regulator activity	2.07119387257991	bayes_pls_golite062009
coenzyme binding	1.94345417147733	bayes_pls_golite062009
binding	1.76189957257133	bayes_pls_golite062009
nitric-oxide synthase activity	1.73361245661515	bayes_pls_golite062009
cytochrome-b5 reductase activity	1.5685421124725	bayes_pls_golite062009
ferredoxin-NADP+ reductase activity	1.46342400843015	bayes_pls_golite062009
ferredoxin reductase activity	1.46342400843015	bayes_pls_golite062009
oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor	1.46342400843015	bayes_pls_golite062009
catalytic activity	1.45374095556065	bayes_pls_golite062009
phosphoric diester hydrolase activity	1.30413377266725	bayes_pls_golite062009
monooxygenase activity	1.24895114339483	bayes_pls_golite062009
NADP or NADPH binding	1.18833847639357	bayes_pls_golite062009
demethylase activity	1.1768217851058	bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	1.11231803143399	bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen	0.878188072733981	bayes_pls_golite062009
transferase activity	0.708491789248912	bayes_pls_golite062009
FMN binding	0.649158247260553	bayes_pls_golite062009
NAD(P)H oxidase activity	0.46219666758416	bayes_pls_golite062009
riboflavin synthase activity	0.380537461428523	bayes_pls_golite062009
protein binding	0.244726474314668	bayes_pls_golite062009
cofactor binding	0.205324283520452	bayes_pls_golite062009
transcription factor binding	0.065157440608373	bayes_pls_golite062009
cytoskeletal protein binding	0.0373671593900911	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: