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View Structure Prediction Details

Protein: nup124
Organism: Schizosaccharomyces pombe
Length: 1159 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nup124.

Description E-value Query
Range
Subject
Range
gi|39592304, gi|... - gi|39592304|emb|CAE75525.1| Hypothetical protein CBG23547 [Caenorhabditis briggsae], gi|187020927|em...
gi|157762282 - gi|157762282|ref|XP_001673483.1| Hypothetical protein CBG23547 [Caenorhabditis briggsae AF16]
426.0 [0..3] [1158..418]
SPBPJ4664.02 - glycoprotein
YHU2_SCHPO - Uncharacterized threonine-rich GPI-anchored glycoprotein PJ4664.02 OS=Schizosaccharomyces pombe (str...
398.0 [0..3] [1155..947]
gi|33310026 - gi|33310026|gb|AAQ03243.1|AF414112_1 putative cell wall protein FLO11p [Candida albicans]
gi|68482880, gi|... - gi|68482880|ref|XP_714666.1| putative cell wall adhesin [Candida albicans SC5314], gi|46436253|gb|EA...
368.0 [0..116] [1152..56]
MUC17 - mucin 17, cell surface associated
368.0 [0..6] [1154..1404]
gi|55380423, gi|... - gi|56307416|ref|NP_787974.3| dumpy CG33196-PB [Drosophila melanogaster], gi|55380423|gb|AAN10358.4| ...
347.0 [0..7] [1156..5207]
gi|37930527, gi|... - gi|37930527|gb|AAP74661.1| elicitor-like transglutaminase M81 [Phytophthora infestans], gi|23505399|...
345.0 [0..12] [1092..502]

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Predicted Domain #1
Region A:
Residues: [1-422]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPVSKNTRT SSKTVKKPYD PPQGSSRPFF TVLKRAFSSV LHPFTSGLDE KASGTASKDR  60
   61 KSGRAGTKSL LTPELTPHYL GKSPRIIRVS NRSHVRTIDG IEEKVHTNTF EPRKPKQKQD 120
  121 YTNSPTLFKR HDELSLKSLN SLHPSSALSK KLGSTSQHQI ATPKSSASLL NILRSLHDEQ 180
  181 KNTLNISSVK QDRITEANPT CEKRKPSRSP SPMLSKKKSV ARASENEPSA KQNKSFSGND 240
  241 SHKSLTDIRD KENGETEVSA KNHVPHRSSR RRRRHQRLIP IIYETLEQMD LRKPVLVNAE 300
  301 VQTDSNPGNT MFIDKQDIYH RLSTPTSRKR QTLEKGHIKA FSAVDEDLDE IFACEDDVHY 360
  361 TALPKQNPKS ERILEPIIAS PKDNTSDKGL LTKSAPTFEE LQASITPKPV KTSPNDTALT 420
  421 LA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.03
Match: 1omwA
Description: G-protein coupled receptor kinase 2, N-terminal domain; G-protein coupled receptor kinase 2 (beta-adrenergic receptor kinase 1); G-protein coupled receptor kinase 2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.22428758317736 bayes_pls_golite062009
protein binding 1.54961752900242 bayes_pls_golite062009
protein kinase activity 1.31419329313343 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.20088944410496 bayes_pls_golite062009
transporter activity 1.14487771276691 bayes_pls_golite062009
transmembrane receptor activity 1.06759196344598 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.04308738565528 bayes_pls_golite062009
receptor activity 1.02162548955804 bayes_pls_golite062009
transmembrane transporter activity 0.994293779520251 bayes_pls_golite062009
kinase activity 0.989702565083208 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.833831720654728 bayes_pls_golite062009
substrate-specific transporter activity 0.724052049967156 bayes_pls_golite062009
Ran GTPase binding 0.709291241748316 bayes_pls_golite062009
molecular transducer activity 0.695021063527918 bayes_pls_golite062009
signal transducer activity 0.695021063527918 bayes_pls_golite062009
transferase activity 0.624121946809127 bayes_pls_golite062009
catalytic activity 0.593995061424214 bayes_pls_golite062009
ATP binding 0.572345879629496 bayes_pls_golite062009
protein serine/threonine kinase activity 0.566982635339813 bayes_pls_golite062009
adenyl ribonucleotide binding 0.541384252517142 bayes_pls_golite062009
adenyl nucleotide binding 0.534108415835127 bayes_pls_golite062009
purine nucleotide binding 0.521108494674166 bayes_pls_golite062009
purine ribonucleotide binding 0.521107326648506 bayes_pls_golite062009
ribonucleotide binding 0.521095364461424 bayes_pls_golite062009
nucleotide binding 0.515729013116388 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.468575645137665 bayes_pls_golite062009
transmembrane receptor protein tyrosine kinase activity 0.415062676534168 bayes_pls_golite062009
ion transmembrane transporter activity 0.16568361458757 bayes_pls_golite062009
protein tyrosine kinase activity 0.0997896740350728 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.0229080352184639 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [423-511]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NAEDNKTFEH QPLSKDTEAP KSQFSSSPTK ESTTRKSEVE PPSPSKEIKS SHFSVPEFKF  60
   61 EPKTEATTDK KLNVPKFEFK PTATADVQT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [512-635]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRLKENEPKP TFFAQLPSKT QETPSITENK PSFFSQLSPK REETEKKDNA PSAPASTSGF  60
   61 SFGGFAPKTL EEKEETKAPT FNFSLNNASS TQDTTKPTLQ FNFGSSFGKP TSNIFNDKKT 120
  121 SENG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [636-768]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LASSTVASES KPSAPESKPS SGFGNTAGSS PFSFNLTKES KEVPPTNSFS FAKKGKDEAN  60
   61 DSLSAKASTP FSFAKPNTEN VTTTAPQFSF NFTKPNTDAK TNLLPEKTFN EEAVKQKETE 120
  121 KEVPPTGPKA SEI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [769-1002]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDSVSSNNAV PSSTFNFVSP FAAVSEKTNE NNIPNDTTKT NGNATKRTLE QTEDAKPFAF  60
   61 SFGSTTEQAN KKASTSNETT KPQLDTSSKT DGVTANAPFS FASAFNAPKP STNTADGKDS 120
  121 ASNLTTPSPA FSFGNNSGVK ASSNNNPSTN SSTAPFSFGT SNKPAFSFGS ATSKTTSEGT 180
  181 APAASASAPA PTTSAFSFGA SNSSMNKEEN TPMAKDAGDT APASGFKSGF SFGA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1003-1159]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNSPQPASMF GTSTPAPSSA FAFGNQSGTN PAAPAGFGGI TNTATNNPPS TGFTFTPSNA  60
   61 GSTAAPMFGA GNTPNPSGSI NNASQAFAFG SGEPSNPASN PPSTGFSFGA ATPSAFNASA 120
  121 SQSPAPNGIQ FNLGSSNSQT NAPPGRKIAV PRSRRKR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle