YRC Public Data Repository - Protein Structure Prediction

Protein:	mpr1
Organism:	Schizosaccharomyces pombe
Length:	295 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mpr1.

Description	E-value	Query Range	Subject Range
gi\|98660701 - gi\|98660701\|dbj\|GAA02123.1\| unnamed protein product [Pelotomaculum thermopropionicum SI]	178.0	[0..4]	[234..116]
gi\|110801119, gi... - gi\|110801119\|ref\|YP_695076.1\| DNA-binding response regulator [Clostridium perfringens ATCC 13124], g...	172.0	[0..4]	[230..15]
gi\|18144301, gi\|... - gi\|18309624\|ref\|NP_561558.1\| DNA-binding response regulator [Clostridium perfringens str. 13], gi\|18...	171.0	[0..4]	[230..15]
gi\|28210824, gi\|... - gi\|28210824\|ref\|NP_781768.1\| transcriptional regulatory protein [Clostridium tetani E88], gi\|2820326...	171.0	[0..4]	[232..15]
gi\|82402957, gi\|... - gi\|82499061\|ref\|ZP_00884513.1\| Response regulator receiver [Caldicellulosiruptor saccharolyticus DSM...	170.0	[0..6]	[232..14]
gi\|150017114, gi... - gi\|82745847\|ref\|ZP_00908357.1\| Response regulator receiver [Clostridium beijerincki NCIMB 8052], gi\|...	169.0	[0..3]	[230..13]
gi\|110682378, gi... - gi\|110801877\|ref\|YP_697936.1\| DNA-binding response regulator [Clostridium perfringens SM101], gi\|110...	169.0	[0..4]	[230..15]
gi\|163939206, gi... - gi\|89204474\|ref\|ZP_01183051.1\| Response regulator receiver:Transcriptional regulatory protein, C-ter...	168.0	[0..4]	[232..15]
gi\|42780487, gi\|... - gi\|42780487\|ref\|NP_977734.1\| DNA-binding response regulator [Bacillus cereus ATCC 10987], gi\|4273640... gi\|222095033, gi... - gi\|222095033\|ref\|YP_002529093.1\| response regulator [Bacillus cereus Q1], gi\|221239091\|gb\|ACM11801.1... gi\|217068126, gi... - gi\|217958874\|ref\|YP_002337422.1\| DNA-binding response regulator [Bacillus cereus AH187], gi\|21706812... gi\|206977570, gi... - gi\|206977570\|ref\|ZP_03238464.1\| DNA-binding response regulator [Bacillus cereus H3081.97], gi\|206744...	168.0	[0..4]	[232..15]

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Predicted Domain #1

Region A:
Residues: [1-295]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVYRDNMYM KYDRNFENRV ARRNGQARNA SLAKTLHDSG IAERARSPSG SAIPHAYRVM  60
   61 NGSGANDTSL PLTSNPAYVA LTSRISSSKS ENNQQLAANE TAGAPEGTEE TVDISNSISD 120
  121 DHANAKNLPA ASVKALVGAG VLSDELSVIA YDMSFEDELI QDKQLIDHSV FDQLLEMDDD 180
  181 DEHEFSKSIV WNYFEQAETT IADLQKALEA KDLKKLSSLG HFLKGSSAVL GLTKMRKVCE 240
  241 RIQNYGSLRS RDGVMKLPSE EIALDLISKS LSVVNDFYKD ARAYLLDFYE KNSST

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	19.522879
Match:	1ny5A
Description:	Crystal structure of sigm54 activator (AAA+ ATPase) in the inactive state
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.64537357529343	bayes_pls_golite062009
nucleoside-triphosphatase activity	1.25199568529204	bayes_pls_golite062009
pyrophosphatase activity	1.24782523585835	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.22648706271393	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.22550815008117	bayes_pls_golite062009
purine ribonucleotide binding	1.21658213854831	bayes_pls_golite062009
ribonucleotide binding	1.21652144153182	bayes_pls_golite062009
purine nucleotide binding	1.21571071905795	bayes_pls_golite062009
nucleotide binding	1.20347573865566	bayes_pls_golite062009
hydrolase activity	1.12362314057799	bayes_pls_golite062009
nucleic acid binding	0.777787753097919	bayes_pls_golite062009
DNA-dependent ATPase activity	0.75383985982414	bayes_pls_golite062009
guanyl nucleotide binding	0.656009904481476	bayes_pls_golite062009
guanyl ribonucleotide binding	0.64416740142962	bayes_pls_golite062009
GTP binding	0.643084645864898	bayes_pls_golite062009
DNA binding	0.479412476059825	bayes_pls_golite062009
GTPase activity	0.406399103964327	bayes_pls_golite062009
helicase activity	0.31983709186498	bayes_pls_golite062009
transcription regulator activity	0.312171320541728	bayes_pls_golite062009
structure-specific DNA binding	0.229327589367146	bayes_pls_golite062009
ATP binding	0.20901529484652	bayes_pls_golite062009
adenyl ribonucleotide binding	0.193888824779002	bayes_pls_golite062009
adenyl nucleotide binding	0.176038316016909	bayes_pls_golite062009
protein binding	0.170837278876362	bayes_pls_golite062009
microtubule motor activity	0.0893162371395102	bayes_pls_golite062009
motor activity	0.0216993813758501	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: