YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC56F8.03
Organism:	Schizosaccharomyces pombe
Length:	1079 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC56F8.03.

Description	E-value	Query Range	Subject Range
EFG2_METCA - Elongation factor G 2 OS=Methylococcus capsulatus GN=fusA2 PE=3 SV=1 EFG2_METCA - Elongation factor G 2 OS=Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath) GN=fusA2 ...	492.0	[0..475]	[1078..1]
EFG_PHOLL - Elongation factor G OS=Photorhabdus luminescens subsp. laumondii GN=fusA PE=3 SV=1 EFG_PHOLL - Elongation factor G OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT...	488.0	[0..475]	[1077..1]
gi\|24114604, gi\|... - gi\|24114604\|ref\|NP_709114.1\| GTP-binding protein chain elongation factor EF-G [Shigella flexneri 2a ...	488.0	[0..475]	[1077..1]
EFG_GEOKA - Elongation factor G OS=Geobacillus kaustophilus GN=fusA PE=3 SV=1 EFG_GEOKA - Elongation factor G OS=Geobacillus kaustophilus (strain HTA426) GN=fusA PE=3 SV=1	485.0	[0..475]	[1079..1]
EFG_ERWCT - Elongation factor G OS=Erwinia carotovora subsp. atroseptica GN=fusA PE=3 SV=1 EFG_PECAS - Elongation factor G OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) GN=fusA PE=3 SV...	485.0	[0..475]	[1077..1]
EFG_SHIFL - Elongation factor G OS=Shigella flexneri GN=fusA PE=3 SV=3 EFG_SHIF8 - Elongation factor G OS=Shigella flexneri serotype 5b (strain 8401) GN=fusA PE=3 SV=1	485.0	[0..475]	[1077..1]
EFG1_GEOMG - Elongation factor G 1 OS=Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) GN=fusA1 P...	485.0	[0..483]	[1079..9]
EG10360 - protein chain elongation factor EF-G, GTP-binding / Elongation Factor EF-G; GTPase required for tran... sp\|B7UK50\|EFG_ECO27 - Elongation factor G OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=fusA PE=3 SV=1 gi\|227839353, gi... - gi\|227883474\|ref\|ZP_04001279.1\| elongation factor G [Escherichia coli 83972], gi\|227839353\|gb\|EEJ498... gi\|226902335, gi... - gi\|237703071\|ref\|ZP_04533552.1\| elongation factor G [Escherichia sp. 3_2_53FAA], gi\|226902335\|gb\|EEH... EFG_ECOBW - Elongation factor G OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=fusA PE=3 SV=1 gi\|251786594, gi... - gi\|251786594\|ref\|YP_003000898.1\| hypothetical protein B21_03142 [Escherichia coli BL21], gi\|24237886... gi\|254290018, gi... - gi\|254290018\|ref\|YP_003055766.1\| elongation factor EF-2 [Escherichia coli BL21(DE3)], gi\|253979325\|g... gi\|254038502, gi... - gi\|254038502\|ref\|ZP_04872558.1\| translation elongation factor G [Escherichia sp. 1_1_43], gi\|2268390... gi\|253975169, gi... - gi\|254163268\|ref\|YP_003046376.1\| elongation factor EF-2 [Escherichia coli B str. REL606], gi\|2539751... gi\|254795263, gi... - gi\|254795263\|ref\|YP_003080100.1\| protein chain elongation factor EF-G, GTP-binding [Escherichia coli... EFG_ECOUT - Elongation factor G OS=Escherichia coli (strain UTI89 / UPEC) GN=fusA PE=3 SV=3 gi\|85676701, gi\|... - gi\|89110670\|ref\|AP_004450.1\| protein chain elongation factor EF-G [Escherichia coli str. K-12 substr... EFG_SHIDS - Elongation factor G OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=fusA PE=3 SV=1 EFG_SHIBS - Elongation factor G OS=Shigella boydii serotype 4 (strain Sb227) GN=fusA PE=3 SV=1 EFG_ECO24 - Elongation factor G OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=fusA PE=3 SV=1 EFG_ECOHS - Elongation factor G OS=Escherichia coli O9:H4 (strain HS) GN=fusA PE=3 SV=1 gi\|194421097, gi... - gi\|83584692\|ref\|ZP_00923358.1\| COG0480: Translation elongation factors (GTPases) [Escherichia coli 1... EFG_SHIB3 - Elongation factor G OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=fusA PE=3 SV=1 EFG_SHISS - Elongation factor G OS=Shigella sonnei (strain Ss046) GN=fusA PE=3 SV=1 EFG_ECOL6 - Elongation factor G OS=Escherichia coli O6 GN=fusA PE=3 SV=2 gi\|190908223, gi... - gi\|75241565\|ref\|ZP_00725410.1\| COG0480: Translation elongation factors (GTPases) [Escherichia coli F... gi\|188496268, gi... - gi\|75511244\|ref\|ZP_00733946.1\| COG0480: Translation elongation factors (GTPases) [Escherichia coli 5... EFG_ECOLI - Elongation factor G (EF-G) - Escherichia coli EFG_ECOL6 - Elongation factor G OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=fusA PE=3 SV=2 EFG_ECO57 - Elongation factor G OS=Escherichia coli O157:H7 GN=fusA PE=3 SV=2 EG10360 - protein chain elongation factor EF-G, GTP-binding / Elongation Factor EF-G; GTPase required for tran... gi\|15803853, gi\|... - gi\|15803853\|ref\|NP_289887.1\| elongation factor G [Escherichia coli O157:H7 EDL933], gi\|12517958\|gb\|A... EFG_ECOK1 - Elongation factor G OS=Escherichia coli O1:K1 / APEC GN=fusA PE=3 SV=1 EFG_ECOSM - Elongation factor G OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=fusA PE=3 SV=1 EFG_ECODH - Elongation factor G OS=Escherichia coli (strain K12 / DH10B) GN=fusA PE=3 SV=1 gi\|195940526 - gi\|195940526\|ref\|ZP_03085908.1\| elongation factor G [Escherichia coli O157:H7 str. EC4024] gi\|170769536, gi... - gi\|170769536\|ref\|ZP_02903989.1\| translation elongation factor G [Escherichia albertii TW07627], gi\|1... gi\|13363664, gi\|... - gi\|15833445\|ref\|NP_312218.1\| elongation factor G [Escherichia coli O157:H7 str. Sakai], gi\|13363664\|... gi\|208738386, gi... - gi\|208818263\|ref\|ZP_03258583.1\| translation elongation factor G [Escherichia coli O157:H7 str. EC404... EFG_ECOL5 - Elongation factor G OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=fusA PE=3 SV=3 gi\|208735369, gi... - gi\|208814092\|ref\|ZP_03255421.1\| translation elongation factor G [Escherichia coli O157:H7 str. EC404... EFG_ECOSE - Elongation factor G OS=Escherichia coli (strain SE11) GN=fusA PE=3 SV=1 EFG_ECO5E - Elongation factor G OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=fusA PE=3 SV=1 gi\|168769195, gi... - gi\|189361768\|gb\|EDU80187.1\| translation elongation factor G [Escherichia coli O157:H7 str. EC4486], ... gi\|189374437, gi... - gi\|189374437\|gb\|EDU92853.1\| translation elongation factor G [Escherichia coli O157:H7 str. EC869], g... gi\|188998495, gi... - gi\|188998495\|gb\|EDU67487.1\| translation elongation factor G [Escherichia coli O157:H7 str. EC4076], ... gi\|217326168, gi... - gi\|217326168\|ref\|ZP_03442252.1\| translation elongation factor G [Escherichia coli O157:H7 str. TW145... EFG_ECO27 - Elongation factor G OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=fusA PE=3 SV=1 EFG_ECO8A - Elongation factor G OS=Escherichia coli O8 (strain IAI1) GN=fusA PE=3 SV=1 EFG_ESCF3 - Elongation factor G OS=Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73) GN=fusA ... EFG_ECOLC - Elongation factor G OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=fusA PE=3 SV=1 EFG_ECO81 - Elongation factor G OS=Escherichia coli O81 (strain ED1a) GN=fusA PE=3 SV=1 EFG_ECO45 - Elongation factor G OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=fusA PE=3 SV=1 EFG_ECO7I - Elongation factor G OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=fusA PE=3 SV=1 EFG_ECO55 - Elongation factor G OS=Escherichia coli (strain 55989 / EAEC) GN=fusA PE=3 SV=1	484.0	[0..475]	[1077..1]
gi\|133726051, gi... - gi\|254871357\|ref\|ZP_05244067.1\| elongation factor G [Listeria monocytogenes FSL N1-017], gi\|15316881... EFG_LISMO - Elongation factor G OS=Listeria monocytogenes GN=fusA PE=3 SV=1 gi\|153175961, gi... - gi\|254829103\|ref\|ZP_05233790.1\| elongation factor G [Listeria monocytogenes FSL N3-165], gi\|15317596... gi\|254937280, gi... - gi\|254937280\|ref\|ZP_05268977.1\| elongation factor G [Listeria monocytogenes F6900], gi\|153180818\|ref... gi\|254931078, gi... - gi\|254931078\|ref\|ZP_05264437.1\| elongation factor G [Listeria monocytogenes HPB2262], gi\|153204302\|r... EFG_LISMC - Elongation factor G OS=Listeria monocytogenes serotype 4b (strain CLIP80459) GN=fusA PE=3 SV=1 gi\|47092275, gi\|... - gi\|47092275\|ref\|ZP_00230066.1\| translation elongation factor G [Listeria monocytogenes str. 4b H7858... gi\|224503700 - gi\|224503700\|ref\|ZP_03672007.1\| elongation factor G [Listeria monocytogenes FSL R2-561] EFG_LISMF - Elongation factor G OS=Listeria monocytogenes serotype 4b (strain F2365) GN=fusA PE=3 SV=1 EFG_LISMO - Elongation factor G OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=fusA PE=... EFG_LISMC - Elongation factor G OS=Listeria monocytogenes serotype 4b (strain Clip81459) GN=fusA PE=3 SV=1 gi\|254824986 - gi\|254824986\|ref\|ZP_05229987.1\| elongation factor G [Listeria monocytogenes FSL J1-194] gi\|224499327 - gi\|224499327\|ref\|ZP_03667676.1\| elongation factor G [Listeria monocytogenes Finland 1988] gi\|254852047 - gi\|254852047\|ref\|ZP_05241395.1\| elongation factor G [Listeria monocytogenes FSL R2-503] EFG_LISMH - Elongation factor G OS=Listeria monocytogenes serotype 4a (strain HCC23) GN=fusA PE=3 SV=1 gi\|254877783 - gi\|254877783\|ref\|ZP_05250493.1\| elongation factor G [Listeria monocytogenes FSL J2-071] gi\|254993424 - gi\|254993424\|ref\|ZP_05275614.1\| elongation factor G [Listeria monocytogenes FSL J2-064] gi\|255028879 - gi\|255028879\|ref\|ZP_05300830.1\| elongation factor G [Listeria monocytogenes LO28] gi\|255519619 - gi\|255519619\|ref\|ZP_05386856.1\| elongation factor G [Listeria monocytogenes FSL J1-175] gi\|153185587, gi... - gi\|254899895\|ref\|ZP_05259819.1\| elongation factor G [Listeria monocytogenes J0161], gi\|153185587\|ref... gi\|127632856, gi... - gi\|254830913\|ref\|ZP_05235568.1\| elongation factor G [Listeria monocytogenes 10403S], gi\|153197683\|re... gi\|254912899, gi... - gi\|254912899\|ref\|ZP_05262911.1\| elongation factor G [Listeria monocytogenes J2818], gi\|153192412\|ref...	484.0	[0..475]	[1079..1]
gi\|222056708, gi... - gi\|222056708\|ref\|YP_002539070.1\| translation elongation factor G [Geobacter sp. FRC-32], gi\|22156599...	484.0	[0..485]	[1079..11]

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Predicted Domain #1

Region A:
Residues: [1-298]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKKGKKSGY ADWEDDLGED ISGQNEYLDN TSQDSPQNDE LAEKSENLAV SSEKTTSKKK  60
   61 KGKKNKGNKN QVSDDESQEL ESPQGPKELT AVTELDDDEF DYKPKKGKKG KKSKKVEEDD 120
  121 EPQEIESPQG PKELTAVTEL DDDEFDYKPK KGKKGKKAQN NNESEAAAPP EIPEVRVKTK 180
  181 KEKEREKKER EKLRKKQQQA KKKGSTGEDT LASSEVSSEV DISTPAENDS SAKGKQAAGS 240
  241 KRKGPNVTAL QKMLEEKRAR EEEEQRIREE EARIAEEEKR LAEVEEARKE EARLKKKE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	6.154902
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [299-476]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KERKKKEEMK AQGKYLSKKQ KEQQALAQRR LQQMLESGVR VAGLSNGEKK QKPVYTNKKK  60
   61 SNRSGTSSIS SSGILESSPA TSISVDEPQK DSKDDSEKVE KETEVERKEE NEAEAEAVFD 120
  121 DWEAALEEPE VAENNEVVTE KKETDIKSDA VEHSIKDKED SKTDKVDDIP QAAPAESN

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.971
Match:	1rh1A
Description:	crystal structure of the cytotoxic bacterial protein colicin B at 2.5 A resolution
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [477-1079]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSESDLRSPI CCILGHVDTG KTKLLDNLRR SNVQEGEAGG ITQQIGATYF PIESIKQKTK  60
   61 VVNKKGKLQY NIPGLLIIDT PGHESFTNLR SRGTSLCNIA ILVIDIMHGL EPQTIESIRL 120
  121 LRDQKTPFVV ALNKVDRLYG WHSIKDNAIQ DSLSKQKKAI QREFRDRVES IILQLNEQGL 180
  181 NAALYFENKN LGRYVSLVPT SAQSGEGVPD LVALLISLTQ TRMSDRIKYI TTLECTVLEV 240
  241 KVIEGLGATI DVILSNGVLH EGDRIVLCGM GGPIITTVRA LLTPQPLKEM RVKSAYVHHK 300
  301 EIKAAMGVKI CANDLEKAVA GSRLLVVGPD DDEEDLAEEI MEDLENLLGR IDTSGIGVSV 360
  361 QASTLGSLEA LLEFLKQMKI PVASVNIGPV YKKDVMRCAT MLEKAKEYAL MLCFDVKVDR 420
  421 DAEDLAEQLG VKIFSANVIY HLFDAFTAHQ KKILEQKREE SSDVAVFPCV LKTVAAFNKR 480
  481 DPIILGVDVV EGVLRINTPI VAVKQLPNGE PQIIELGRVA SLEMNHKPVD KVKKGQAGAG 540
  541 VAMKLESSGS QILFGRQVTE SDALYSHITR QSIDSLKDPA FRDEVSRDEW QLIIQLKKLF 600
  601 GII

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	78.522879
Match:	1g7rA
Description:	Initiation factor IF2/eIF5b, domains 2 and 4; Initiation factor IF2/eIF5b, domain 3; Initiation factor IF2/eIF5b, N-terminal (G) domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
translation initiation factor activity	5.88857268461955	bayes_pls_golite062009
structural constituent of ribosome	5.41178688428159	bayes_pls_golite062009
structural molecule activity	4.44501073718522	bayes_pls_golite062009
nucleic acid binding	2.02680549811636	bayes_pls_golite062009
binding	1.8340549733034	bayes_pls_golite062009
translation regulator activity	1.62528736558737	bayes_pls_golite062009
translation factor activity, nucleic acid binding	1.60662288414996	bayes_pls_golite062009
DNA binding	1.19966224604123	bayes_pls_golite062009
motor activity	1.14667913749579	bayes_pls_golite062009
transcription regulator activity	1.09075553688438	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
protein binding	0.871734119777931	bayes_pls_golite062009
peptidyltransferase activity	0.696276842950831	bayes_pls_golite062009
microtubule motor activity	0.60036517876321	bayes_pls_golite062009
purine nucleotide binding	0.569910969126728	bayes_pls_golite062009
purine ribonucleotide binding	0.568840867400671	bayes_pls_golite062009
ribonucleotide binding	0.568779924702229	bayes_pls_golite062009
nucleotide binding	0.564275755355315	bayes_pls_golite062009
cytoskeletal protein binding	0.500462538667228	bayes_pls_golite062009
RNA helicase activity	0.2302541318658	bayes_pls_golite062009
ATP binding	0.1860481660648	bayes_pls_golite062009
adenyl ribonucleotide binding	0.152859582615242	bayes_pls_golite062009
adenyl nucleotide binding	0.138615225841109	bayes_pls_golite062009
RNA binding	0.0693163519626152	bayes_pls_golite062009
transcription factor activity	0.0612932659603008	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.0530667986761242	bayes_pls_golite062009
pyrophosphatase activity	0.0482442222493492	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.028470639373934	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.0265151533232588	bayes_pls_golite062009
actin binding	0.00482938540552702	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: