YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: mRNA-capping-enz...
Organism: Drosophila melanogaster
Length: 649 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mRNA-capping-enz....

Description E-value Query
Range
Subject
Range
gi|125981643, gi... - gi|54643136|gb|EAL31880.1| GA14791-PA [Drosophila pseudoobscura], gi|125981643|ref|XP_001354825.1| G...
398.0 [0..1] [638..1]

Back

Predicted Domain #1
Region A:
Residues: [1-215]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALTNRDRER GSGPLPNRWL YCPRKSDTII AERFLAFKTP LSNNFHDKMP IECTFQPEML  60
   61 FEYCKTLKVK LGLWVDLTNT KRFYDRSAVE ELGAKYIKLQ CRGHGETPSP EQTHSFIEIV 120
  121 DNFINERPFD VIAVHCTHGF NRTGFLIVCY LVERLDCSVS AALAIFASAR PPGIYKQDYI 180
  181 NELYKRYEDT NAAPAAPEQP NWCLDYDDGN GDGFV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.39794
Match: 2c46A
Description: CRYSTAL STRUCTURE OF THE HUMAN RNA guanylyltransferase and 5'- phosphatase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [216-448]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QDNSSSTSQQ AGEQDDDAEE VEGEDAGGDC DASTSDGQPR KKRRREMIIK NATFMAGVPG  60
   61 VRQVSDQPRL GDLQRKVQDW CDWKKNGFPG AQPVSMDREN IKRLSEIPYR VSWKADGTRY 120
  121 MMLIDGRDEV YFFDRNHSCF QVENVTFVES RNLNEHLDGT LVDGEMVLDK IGETVTPRYL 180
  181 IYDIVRLSNR DVRDEPFYPN RLDYIKTEVI GPRILGMKHG IINQRLQAFS VRG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.14
Match: 2hivA
Description: No description for 2hivA was found.

Predicted Domain #3
Region A:
Residues: [449-649]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDFWDIWMSA RLLGEKFSRT LAHEPDGLIF QPSKQPYTAG TCSDVFKWKP HELNSVDFRL  60
   61 KIITERGEGL LTKKVGFLYV GGHDAPYGRM QRLTKETREL DNRIVECTMN QFGNWDFMRE 120
  121 RTDKKNPNSY NTARSVVDSI KHPVTKEYLL NFIASSGYRN DHVMMPPPIN SHNQNHNHNH 180
  181 FYPHGHGQHQ RRPCVNPTLG N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.154902
Match: 1p16A
Description: mRNA capping enzyme alpha subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 3.194200758646 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 3.08627215479695 bayes_pls_golite062009
DNA binding 2.71213098011194 bayes_pls_golite062009
binding 2.63617204791771 bayes_pls_golite062009
RNA binding 2.41160981373213 bayes_pls_golite062009
hydrolase activity 2.27001407788735 bayes_pls_golite062009
structure-specific DNA binding 1.81524862921454 bayes_pls_golite062009
structural constituent of ribosome 1.6315894906264 bayes_pls_golite062009
single-stranded DNA binding 1.62996999055328 bayes_pls_golite062009
1.5765009871268 bayes_pls_golite062009
structural molecule activity 1.32534541097134 bayes_pls_golite062009
ribonuclease activity 1.19236946227657 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 1.15212468568198 bayes_pls_golite062009
exoribonuclease activity 1.10445667068538 bayes_pls_golite062009
transcription regulator activity 0.996884322431837 bayes_pls_golite062009
3'-5'-exoribonuclease activity 0.83268201349295 bayes_pls_golite062009
translation regulator activity 0.613904794456162 bayes_pls_golite062009
nuclease activity 0.57381531077345 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.566068090112017 bayes_pls_golite062009
DNA-directed RNA polymerase activity 0.477127926059749 bayes_pls_golite062009
RNA polymerase activity 0.477127926059749 bayes_pls_golite062009
mRNA binding 0.4162128308402 bayes_pls_golite062009
sequence-specific DNA binding 0.32084431704638 bayes_pls_golite062009
translation initiation factor activity 0.30211828233765 bayes_pls_golite062009
transcription factor activity 0.298729064067577 bayes_pls_golite062009
protein binding 0.0528188351789111 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.00388708148970557 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle