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View Structure Prediction Details

Protein: CG11876-PD, CG11...
Organism: Drosophila melanogaster
Length: 365 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG11876-PD, CG11....

Description E-value Query
Range
Subject
Range
gi|115956715, gi... - gi|115956715|ref|XP_001185430.1| PREDICTED: similar to Pyruvate dehydrogenase (lipoamide) beta [Stro...
356.0 [0..22] [361..26]

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Predicted Domain #1
Region A:
Residues: [1-365]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRTRLIQAA SSAQRAFSTS QKALAAKQMT VRDALNSALD DELARDDRVF ILGEEVAQYD  60
   61 GAYKVSRGLW KKYGDKRVID TPITEMGFAG IAVGAAMAGL RPVCEFMTWN FSMQAIDHII 120
  121 NSAAKTFYMS AGAVNVPIVF RGPNGAASGV AAQHSQCFAA WYAHCPGLKV LSPYDAEDAR 180
  181 GLLKSAIRDP DPVVFLENEL VYGTAFPVAD NVADKDFLVP IGKAKVMRPG KDITLVAHSK 240
  241 AVETSLLAAA ELAKKGIEAE VINLRSIRPL DTATIFASVR KTHHLVTVEN GWPQHGVGAE 300
  301 ICARIMEDQT FFELDAPVWR CAGVDVPMPY AKTLEAHALP RVQDLVEATL KVLGGKVGKA 360
  361 AAANK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 91.69897
Match: 1ni4B
Description: E1-beta subunit of pyruvate dehydrogenase, Pyr module; E1-beta subunit of pyruvate dehydrogenase, C-domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
pyruvate dehydrogenase activity 11.3856674722026 bayes_pls_golite062009
pyruvate dehydrogenase (acetyl-transferring) activity 11.0549577473177 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 10.8180381281695 bayes_pls_golite062009
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity 7.00951713446616 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 5.65146926050423 bayes_pls_golite062009
acetolactate synthase activity 4.51986503762195 bayes_pls_golite062009
alpha-ketoacid dehydrogenase activity 2.61614462349133 bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups 2.21959520697519 bayes_pls_golite062009
transketolase activity 2.20554088536433 bayes_pls_golite062009
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer 0.667418924427388 bayes_pls_golite062009
binding 0.551586872853971 bayes_pls_golite062009
catalytic activity 0.545407789079971 bayes_pls_golite062009
oxidoreductase activity 0.281475773435032 bayes_pls_golite062009
pyruvate decarboxylase activity 0.198062360371269 bayes_pls_golite062009

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Created and Maintained by: Michael Riffle