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View Structure Prediction Details

Protein: ird5-PA
Organism: Drosophila melanogaster
Length: 751 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ird5-PA.

Description E-value Query
Range		 Subject
Range
gi|6118518 - gi|6118518|gb|AAF04130.1| IKK-like protein [Drosophila melanogaster]
 372.0 [0..1] [751..1]

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Predicted Domain #1
Region A:
Residues: [1-385] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MITVVFCFSD CHGGIQILGR MSSVNKIKLN ENNKMHSFGN WERCRNLGEG GFGLVIHWRN  60
   61 RTTGREIATK HIKEMGALSA DQQVKLSERW NKELNWSRQF KNFPHIVAGV DIEDPDFLEY 120
  121 LNGMFSAKLP VIVLEYCNGG DVRKRLQSPE NANGLTEFEV RQILGALRKA LHFLHSQCGI 180
  181 CHRDLKPDNI VIQRGVDGKK IYKLTDFGLA RGTPDQTMVQ SVVGTRHYYA PEVVENGFYN 240
  241 STVDLWSFGV IAYELVTGEL PFIPHQTLKN IILNLIKKPA KCIAITEDPE DNTRFVNQFE 300
  301 LPQTHHLSRP WAAQFTKWLA SPLNSNYKER GQLAANNVPV VFADLDKILN MNVLTIFAVN 360
  361 NCERLEYAVS AEMTMKDLIA LIVLD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.0
Match: 1o6kA
Description: Pkb kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphotransferase activity, alcohol group as acceptor 5.49988294224815 bayes_pls_golite062009
kinase activity 5.3287080791198 bayes_pls_golite062009
protein kinase activity 5.17195961442593 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.96052051118534 bayes_pls_golite062009
protein serine/threonine kinase activity 4.46381887831481 bayes_pls_golite062009
transferase activity 3.97138602499442 bayes_pls_golite062009
binding 2.31930216202447 bayes_pls_golite062009
protein binding 2.276111749106 bayes_pls_golite062009
IkappaB kinase activity 2.01337046169267 bayes_pls_golite062009
ATP binding 1.97600611746091 bayes_pls_golite062009
adenyl ribonucleotide binding 1.93596671856664 bayes_pls_golite062009
adenyl nucleotide binding 1.90928021591891 bayes_pls_golite062009
purine ribonucleotide binding 1.65732943334212 bayes_pls_golite062009
ribonucleotide binding 1.65726906484847 bayes_pls_golite062009
purine nucleotide binding 1.63763394711025 bayes_pls_golite062009
nucleotide binding 1.63195828048121 bayes_pls_golite062009
protein tyrosine kinase activity 1.3898059094397 bayes_pls_golite062009
receptor signaling protein serine/threonine kinase activity 1.38496328649031 bayes_pls_golite062009
receptor signaling protein activity 1.27291233344322 bayes_pls_golite062009
catalytic activity 1.21655087018101 bayes_pls_golite062009
transmembrane receptor activity 0.913893847407112 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.821371946077904 bayes_pls_golite062009
receptor activity 0.775180603313375 bayes_pls_golite062009
transporter activity 0.595111702412257 bayes_pls_golite062009
cyclin-dependent protein kinase activity 0.58590430118616 bayes_pls_golite062009
protein serine/threonine/tyrosine kinase activity 0.48345772948903 bayes_pls_golite062009
transmembrane receptor protein tyrosine kinase activity 0.461392047923247 bayes_pls_golite062009
transmembrane transporter activity 0.41384976209545 bayes_pls_golite062009
magnesium ion binding 0.393328812780268 bayes_pls_golite062009
MAP kinase kinase kinase activity 0.37115026509016 bayes_pls_golite062009
MAP kinase kinase activity 0.35402045013148 bayes_pls_golite062009
nucleic acid binding 0.302157011129993 bayes_pls_golite062009
transcription regulator activity 0.300646491604114 bayes_pls_golite062009
signal transducer activity 0.270054246024761 bayes_pls_golite062009
molecular transducer activity 0.270054246024761 bayes_pls_golite062009
DNA binding 0.234035399242102 bayes_pls_golite062009
substrate-specific transporter activity 0.0922946791401962 bayes_pls_golite062009
transcription factor activity 0.071836086792026 bayes_pls_golite062009
transcription activator activity 0.0126825293063959 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.0040394359628233 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [386-751] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGMDEKELYF VLPTSHPHKT ITPKSTPLQL YVEEWSDTSK DSRKWTKRSN PPVMLYIFQV  60
   61 KKECDYKIPE PILSILSRKF IANKFKTKER WLQKRVVLDM LYVLTKEQAR YEMLVSGINE 120
  121 RALSLEDEMM ENSFIDSIDK QRIIISFAYD QLTSLLKEAQ AKIPSRQLIS SAQWEKLNRN 180
  181 YNFIIQSAKS IRSFLEACLR EAKDMVKTTN QLRKEVCEKD LFDCARFYKK YLCNGAIISP 240
  241 SELNNDAEEF AKSRFKLYNE GEARHLPKSI DHMHYLYFKT KESIPVLLQQ FCDIKKEIFQ 300
  301 INLQMLMSAS STPPPKLELS AAMDRLAISS GSPSSDPFDS LRTINAIEEA ERINNILVNE 360
  361 MKIDHY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.30103
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle