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View Structure Prediction Details

Protein: gi|23171428, gi|...
Organism: Drosophila melanogaster
Length: 1929 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|23171428, gi|....

Description E-value Query
Range
Subject
Range
gi|37699520 - gi|37699520|gb|AAB95091.3| 89B helicase [Drosophila melanogaster]
2008.0 [0..10] [1929..4]

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Predicted Domain #1
Region A:
Residues: [1-114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIVFNIPCR LDRLFILLET GSTAATRQAA AKQIGEVQKL YPHELHALLN RLVGYLHSTS  60
   61 WETRIAAAQT VEAILKQVPP WQPEFQVLPK KERCATNTAT AAAAAEEDSC QSSG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [115-286]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNSTTASERL LSFDEFDLQQ ILHKGARLIG SEGNEFDVQE EQPASGGGEE DRSLASRLSR  60
   61 QRAVLNDKLG LTTAAKLGVN LTDMITDEDV ALNRSGSTYN VNAEKLPVEH LLNIKTAANG 120
  121 SGQAPLSCRE MNRAKRKARQ NTSGCSVTAV TPTCSRRNSN SNHSTGSNHS SN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [287-370]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTTGAAIEEP EKKKLKSTDR QEIFYSLNAA VPDATGTWVD AVSWPLENFC SRLFIDLFHA  60
   61 KWEVRHGAAT ALRELINQHA QGAG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [371-1317]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAVLQTREQM DEAHSRWLED AALRLLCVLC LDRFGDFVSD QVVAPVRETC AQVLGTLVKE  60
   61 MEASKVQRIV NILLQLIQHK NEWDVRHGGL LGLKYVFVVR EELLPIYLPQ SISNILIGLL 120
  121 DAVDDVGAVA AATLIPVSSW LPKLLNPAQV SSIVKMLWDL LLDQDELTSA CNSFMGLLAA 180
  181 ILCLPNAARW VEMEPMAILV PRLWPFLSHS TSSVRRSTLK TLMTLTSADR VKSEPKDENQ 240
  241 VKEEADKEEM KLNFGVSDWK WELLQQALRH IYQRILVEPQ ADIQALARQV WSNLIQHADL 300
  301 GALLHAACPF VSSWICLSMQ PPRLAFDAGV LIRAGGDVST PGSTSRKRTP RIGDELGGNI 360
  361 LAQSNASLKL YLGGSEATPL DVRDANFMRA RISSSRALGA LSHYLVQPAP GVVYTPQTES 420
  421 PTDCYTKVLL GHLNAHSAVQ RIVCGLIIAF WALEDEPVRP GPPNLQEKLH QCVSEYVYYD 480
  481 EVAISLTRLL QEAQDFIATL KQNKIPINDF NNAKILTLDQ IEAVATTLSE NLRSYPLKPK 540
  541 VLDMLEERRR SLQASYQQTT SEQSAYHVSA QAALAGAICA LHCLPDKLNP VVKPLMESIK 600
  601 REQCLQLQQL SAEFLVHLMD QVCDRNPSPN SKILNNLCTL LRSDPEFTPK LVMPLETLKQ 660
  661 TPVSSEVINN CVYYGILTLA LQQTVTTTNT RSGAGGATTP TATTAPRGPG RPPTGEILSA 720
  721 TNATAHIELK AQQAKEAEAK QCRIQRLGAA CAIEKLCRIF GEQIIEKVAV FQHLMFGKVE 780
  781 QFVKEAYDWR LGSLLPDLGV CNELVSSMQL IETAAPHLHV ALHPQMFALL PSLGFIVCHP 840
  841 LKAVRHMAAR CIAVLAEIDA CQTMQFVVHD LLPLLGKIEQ LIERQGAIEA IERVVSRLQI 900
  901 KVVPYIVLLV VPLLGAMSDP DESVRLLSTH CFANLVQLMP LDGKTEQ

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.48
Match: 2ie3A
Description: No description for 2ie3A was found.

Predicted functions:

Term Confidence Notes
protein binding 1.94328873922819 bayes_pls_golite062009
binding 1.62122417417421 bayes_pls_golite062009
protein transporter activity 0.943130585917006 bayes_pls_golite062009
nucleic acid binding 0.675283789558554 bayes_pls_golite062009
transporter activity 0.420208786573211 bayes_pls_golite062009
transcription regulator activity 0.222868189542678 bayes_pls_golite062009
catalytic activity 0.0890324459390017 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [1318-1929]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKSDPLQARK TRDREFLDYL FNPKSIPNYK VPVPISVELR CYQQAGINWL WFLNKYNLHG  60
   61 ILCDDMGLGK TLQTICILAG DHMHRQTANL ANLPSLVICP PTLTGHWVYE VEKFLDQGSV 120
  121 LRPLHYYGFP VGREKLRSDI GTKCNLVVAS YDTVRKDIDF FSGIHFNYCV LDEGHIIKNG 180
  181 KTKSSKAIKR LKANHRLILS GTPIQNNVLE LWSLFDFLMP GFLGTEKQFV QRFSRPILSS 240
  241 RDAKSSAKEQ EAGVLAMEAL HRQVLPFLLR RVKEDVLKDL PPKITQDLLC ELSPLQLRLY 300
  301 EDFSNKHLKD CLDKLGDSSS ASMVTENLSA KTHIFQALRY LQNVCNHPKL VLRQSEELTK 360
  361 VTSQLALSNS SLDDIEHSAK LPALKQLLLD CGIGVQTESV SQHRALIFCQ LKAMLDIVEQ 420
  421 DLLRRHLPSV TYLRLDGSVP ASQRQDIVNN FNSDPSIDVL LLTTMVGGLG LNLTGADTVI 480
  481 FVEHDWNPMK DLQAMDRAHR IGQKKVVNVY RLITRNSLEE KIMGLQKFKI LTANTVVSAE 540
  541 NASLQTMGTS QIFDLFNGGK DKGAESGSSA VQGTASGGMS MNTIIENLPE LWSEHQYEEE 600
  601 YDLGNFVQAL KK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 97.522879
Match: 1z3iX
Description: Structure of the SWI2/SNF2 chromatin remodeling domain of eukaryotic Rad54
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleoside-triphosphatase activity 1.69240737024755 bayes_pls_golite062009
pyrophosphatase activity 1.65296291878002 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 1.64318297340116 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.64169398852165 bayes_pls_golite062009
catalytic activity 1.37148167194523 bayes_pls_golite062009
binding 1.30574971150356 bayes_pls_golite062009
ATPase activity 1.20060977637766 bayes_pls_golite062009
transporter activity 1.14815595550467 bayes_pls_golite062009
ATPase activity, coupled 1.08141765801535 bayes_pls_golite062009
transmembrane transporter activity 1.01232806016411 bayes_pls_golite062009
active transmembrane transporter activity 0.92246823619313 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.89546790004613 bayes_pls_golite062009
primary active transmembrane transporter activity 0.89065853471483 bayes_pls_golite062009
hydrolase activity 0.875592967682638 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.8668136831732 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.86536264587818 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.86511385357843 bayes_pls_golite062009
protein binding 0.502813311049029 bayes_pls_golite062009
nucleic acid binding 0.495953203188599 bayes_pls_golite062009
purine ribonucleotide binding 0.3056113353665 bayes_pls_golite062009
ribonucleotide binding 0.30512981340046 bayes_pls_golite062009
purine nucleotide binding 0.30259037403175 bayes_pls_golite062009
nucleotide binding 0.28998663538132 bayes_pls_golite062009
DNA binding 0.128213991729785 bayes_pls_golite062009
transcription regulator activity 0.125640198783258 bayes_pls_golite062009
helicase activity 0.00674361801283974 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle