YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: FBpp0306662, rec-PA
Organism: Drosophila melanogaster
Length: 885 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0306662, rec-PA.

Description E-value Query
Range
Subject
Range
MCM8_MOUSE - DNA helicase MCM8 OS=Mus musculus GN=Mcm8 PE=1 SV=3
537.0 [0..65] [882..20]

Back

Predicted Domain #1
Region A:
Residues: [1-110]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPTLSRGGA PSRFVRGRGR GGGAYRPYFY FRRNGRVIPA GGNRQPNQGE PGAPDAPSVP  60
   61 PATRQPRGWS RTAGKRGRNA HLDCSFLRPE NYAAPEDGLQ VQSIAVDNPR 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [111-269]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AYSGWRLYFL REKYEEGNEL ATRIMAVEAY YQRNPHTFDF VMIRDRGFFP LCAAGIKSDA  60
   61 QLKEVWPSLS EDIREHPLRT LGTLSLAMHT VVVNHQLDCN DSTTAMVSTP EQYVLPTPRV 120
  121 RKIYARPDDF VPVESIEGIS HSRVDTLFSI RGFVSNVGE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.39794
Match: 1ltlA
Description: DNA replication initiator (cdc21/cdc54) N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [270-703]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSYSLTWQAF RCSRCQMEIA MRQRGTFQPR PYQCKRSECV ARDEFVPLRS SPYTRLSIRQ  60
   61 IIRVEESSLN LVHDFETSMP AEMDVELRHD LVDAVRVGQE VVVTGILKLQ ELGDDTTTGD 120
  121 TSNQMQPYLK AVSIRDASSI KREFSERDLE AIVMINAEPN SFKLLVQSIA PEVYGHELPK 180
  181 AACLLSLLGG KGAETEAINV LLVGDPGIGK TKILQSCAQI AERGAHVSGK RGAQSAQQLG 240
  241 VTFAGRNKRV LQAGSLMMAS GGGHCTLDDV DKLASKQAVL LQCLQSEEVN LPLAGAFASF 300
  301 PAQPSVIACA NPQRGQYDEG RYLLQNINIS PSLLREFHLV YILLDKPSER DMSLTAHVRA 360
  361 LHAGARKRAR IAARYALKPK MSDSMCEVSL NVPAAGKDDD TIKTEDDNDS IMQQDYDLDK 420
  421 RLEVLPEEGD LDLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.0
Match: 1ksfX
Description: N-terminal, ClpS-binding domain of ClpA, an Hsp100 chaperone; ClpA, an Hsp100 chaperone, AAA+ modules
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA clamp loader activity 3.94645534451735 bayes_pls_golite062009
protein-DNA loading ATPase activity 3.91355858456767 bayes_pls_golite062009
DNA-dependent ATPase activity 2.72462789867829 bayes_pls_golite062009
DNA helicase activity 2.2817164193758 bayes_pls_golite062009
binding 2.05253348982328 bayes_pls_golite062009
pyrophosphatase activity 2.04806869603661 bayes_pls_golite062009
ATP-dependent DNA helicase activity 1.88455339138556 bayes_pls_golite062009
helicase activity 1.70242731830224 bayes_pls_golite062009
microtubule motor activity 1.6537049553461 bayes_pls_golite062009
nucleic acid binding 1.49633029954726 bayes_pls_golite062009
motor activity 1.32129340699286 bayes_pls_golite062009
purine NTP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
ATP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
DNA binding 0.967303417236485 bayes_pls_golite062009
DNA polymerase activity 0.795745617990735 bayes_pls_golite062009
structure-specific DNA binding 0.782430219754236 bayes_pls_golite062009
DNA-directed DNA polymerase activity 0.771854032852428 bayes_pls_golite062009
transcription regulator activity 0.748437190903548 bayes_pls_golite062009
double-stranded DNA binding 0.6071273686445 bayes_pls_golite062009
protein binding 0.508848095576342 bayes_pls_golite062009
nucleotidyltransferase activity 0.367559137329714 bayes_pls_golite062009
nucleotide binding 0.114848452385726 bayes_pls_golite062009
purine nucleotide binding 0.10713474095071 bayes_pls_golite062009
purine ribonucleotide binding 0.0916519414118148 bayes_pls_golite062009
ribonucleotide binding 0.0915913646217636 bayes_pls_golite062009
structural constituent of ribosome 0.089234257580272 bayes_pls_golite062009
four-way junction helicase activity 0.0763022821830703 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.0530667986761242 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.028470639373934 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0265151533232588 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [704-885]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPILIKKFLS YARQELNPVL NEDASNAVLR YFLELKGSCN LDEDVSSQIG AGQLLAIIHL  60
   61 SQARARLDLS HVVSPQHVRD VIALLTESIT QTSLKEGSSR QGTRGGGGAG GGAGKSAQLR 120
  121 NFLELTKRRS AALGRRIFEF DELKEIGTRA GILTGFSQLV EMANLGGYLL MKGANMYEVV 180
  181 PD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.30103
Match: 2ce7A
Description: EDTA treated
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle