YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: Ir84a-PA
Organism: Drosophila melanogaster
Length: 693 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Ir84a-PA.

Description E-value Query
Range
Subject
Range
gi|50729903 - gi|50729903|ref|XP_416697.1| PREDICTED: similar to Glutamate receptor, ionotropic, kainate 1 isoform...
473.0 [0..35] [693..497]

Back

Predicted Domain #1
Region A:
Residues: [1-132]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTYKNARGP AQSKHKSPKN ESVLKWPYKM IKLQVKVISW PLIILTAFLR VLQIESINTN  60
   61 FLELAAFEDF LRSEHLSHVL VVRGDDADGD WKIECHQKLL ANYRVQFYRP EMSANFEDLM 120
  121 FYGSPRTAVL VL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [133-252]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSEHVLVRRQ VFGVASEAGY FNNSLAWFIL GSGRESLPVE QLIDQLLSGY RMGIDADITV  60
   61 ALRGPDNASM LFYDVYRISR QANTPLIIEK KGLWTHSGGY QKFGNFKNTW VIRRRNFLNV 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.69897
Match: 2e4zA
Description: No description for 2e4zA was found.

Predicted Domain #3
Region A:
Residues: [253-514]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLIGSTVVGC LPNTSPRSLT TYLQIPQLTE KPPGFGDMEY LADDKQLQQL DPMQRKTYQL  60
   61 FQLVERMFNL SLAISLTDKW GELLDNGSWS GVMGQVTSRE ADFAVCPIRF VLDRQPYVQY 120
  121 SAVLHTQNIH FLFRHPRRSH IKNIFFEPLS NQVWWCVLAL VTGSTILLLF HVRLERMLSN 180
  181 MENRFSFVWF TMLETYLQQG PANEIFRLFS TRLLISLSCI FSFMLMQFYG AFIVGSLLSE 240
  241 SARSIVNLQA LYDSNLAIGM EN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.69897
Match: 1pb8A
Description: N-methyl-D-aspartate receptor subunit 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
amine binding 2.25634377868866 bayes_pls_golite062009
binding 1.99193554770277 bayes_pls_golite062009
receptor activity 1.74349172783363 bayes_pls_golite062009
signal transducer activity 1.44487216360172 bayes_pls_golite062009
molecular transducer activity 1.44487216360172 bayes_pls_golite062009
peptide binding 1.01178416544223 bayes_pls_golite062009
nucleic acid binding 0.650797312673016 bayes_pls_golite062009
transporter activity 0.592106222356256 bayes_pls_golite062009
substrate-specific transporter activity 0.566902324147088 bayes_pls_golite062009
transcription factor activity 0.392543807732656 bayes_pls_golite062009
transmembrane transporter activity 0.385015934033076 bayes_pls_golite062009
DNA binding 0.366854341510606 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.0690147885410379 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.0523977889638052 bayes_pls_golite062009
pyrophosphatase activity 0.0130164106420343 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [515-693]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISYNFPIFTN TSNQLVRDVY VKKICKSGEH NIMSLQQGAE RIIQGRFAFH TAIDRMYRLL  60
   61 LELQMDEAEF CDLQEVMFNL PYDSGSVMPK GSPWREHLAH ALLHFRATGL LQYNDKKWMV 120
  121 RRPDCSLFKT SQAEVDLEHF APALFALALA MVASALVFLL ELFLHWLPDF RRRLGTMST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.522879
Match: 1yaeA
Description: Structure of the Kainate Receptor Subunit GluR6 Agonist Binding Domain Complexed with Domoic Acid
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle