YRC Public Data Repository - Protein Structure Prediction

Protein:	aay-PA
Organism:	Drosophila melanogaster
Length:	270 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for aay-PA.

Description	E-value	Query Range	Subject Range
gi\|26453787, gi\|... - gi\|26553780\|ref\|NP_757714.1\| cation-transporting p-type ATPase [Mycoplasma penetrans HF-2], gi\|26453...	169.0	[0..2]	[266..189]
gi\|145408869, gi... - gi\|82499630\|ref\|ZP_00885070.1\| ATPase, E1-E2 type:Copper ion-binding:Copper-translocating P-type ATP...	164.0	[0..3]	[265..501]
gi\|46199082, gi\|... - gi\|46199082\|ref\|YP_004749.1\| putative cation-transporting ATPase pacL [Thermus thermophilus HB27], g...	163.0	[0..2]	[266..294]
gi\|55772523, gi\|... - gi\|55981110\|ref\|YP_144407.1\| cation-transporting ATPase [Thermus thermophilus HB8], gi\|55772523\|dbj\|...	162.0	[0..2]	[266..294]
gi\|18144214, gi\|... - gi\|18309537\|ref\|NP_561471.1\| copper-translocating P-type ATPase [Clostridium perfringens str. 13], g...	160.0	[0..4]	[267..571]
gi\|2622102, gi\|1... - gi\|2622102\|gb\|AAB85497.1\| cation-transporting P-ATPase PacL [Methanothermobacter thermautotrophicus ... gi\|7436365 - pir\|\|E69000 cation-transporting P-ATPase PacL - Methanobacterium thermoautotrophicum (strain Delta H...	158.0	[0..2]	[266..314]
gi\|89897256, gi\|... - gi\|89897256\|ref\|YP_520743.1\| hypothetical protein DSY4510 [Desulfitobacterium hafniense Y51], gi\|893...	158.0	[0..3]	[267..500]
gi\|76151977 - gi\|76151977\|gb\|ABA39707.1\| TcrA [Enterococcus faecium]	157.0	[0..4]	[266..492]
gi\|110683922, gi... - gi\|110803421\|ref\|YP_697846.1\| copper-translocating P-type ATPase [Clostridium perfringens SM101], gi...	157.0	[0..4]	[267..571]
gi\|28210589, gi\|... - gi\|28210589\|ref\|NP_781533.1\| copper efflux ATPase [Clostridium tetani E88], gi\|28203027\|gb\|AAO35470....	156.0	[0..3]	[267..350]

Back

Predicted Domain #1

Region A:
Residues: [1-270]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGSVLSLAR PAAATNGHNL LTKQLNCNGN GTTGGAAKTT VASAITPPKQ PQLAAKVIQQ  60
   61 SQIVCFDVDS TVICEEGIDE LAEYCGKGSE VARVTKEAMG GAMTFQDALK IRLNIIRPTQ 120
  121 QQVRDFIQER PSTLSKNVKR FVSHLKAEGK QVYLISGGFD CLIAPVANEL GIPLKNVYAN 180
  181 KMLFDYLGEY DSFDINQPTS RSGGKAEAIA LIRKENSDDS LITMIGDGAT DLEAVPPANY 240
  241 FIGFGGNVVR PEVYRRAQYY VTDFEQLMGQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.09691
Match:	1nnlA
Description:	Phosphoserine phosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoserine phosphatase activity	2.609399110972	bayes_pls_golite062009
hydrolase activity	1.64652153606264	bayes_pls_golite062009
catalytic activity	1.55296860681783	bayes_pls_golite062009
transporter activity	1.14896368703744	bayes_pls_golite062009
transmembrane transporter activity	1.05797491861618	bayes_pls_golite062009
substrate-specific transporter activity	0.993187180025513	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.927418188183455	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	0.90274219445561	bayes_pls_golite062009
ion transmembrane transporter activity	0.877641462417465	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	0.851191468282636	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism	0.787963367346595	bayes_pls_golite062009
cation transmembrane transporter activity	0.579515117605331	bayes_pls_golite062009
ATPase activity, coupled	0.53313021679328	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.506075412583888	bayes_pls_golite062009
calcium ion transmembrane transporter activity	0.493750063720989	bayes_pls_golite062009
active transmembrane transporter activity	0.478053552351263	bayes_pls_golite062009
pyrophosphatase activity	0.457373743206143	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.436378691321164	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.435443892463434	bayes_pls_golite062009
ATPase activity	0.430637728534119	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	0.403861776663831	bayes_pls_golite062009
primary active transmembrane transporter activity	0.402056642959593	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	0.375649206782765	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	0.375649206782765	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	0.374004042755094	bayes_pls_golite062009
binding	0.309823128403058	bayes_pls_golite062009
metal ion transmembrane transporter activity	0.273204868537985	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.204834938376666	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.117331448391929	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: