YRC Public Data Repository - Protein Structure Prediction

Protein:	PA2GA_RAT
Organism:	Rattus norvegicus
Length:	146 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PA2GA_RAT.

Description	E-value	Query Range	Subject Range
gi\|206322, gi\|15... - gi\|206322\|gb\|AAA41920.1\| phospholipase A2 precursor (EC 3.1.1.4), gi\|155369736\|ref\|NP_113786.2\| phos...	169.0	[0..1]	[146..1]
gi\|45934756, gi\|... - gi\|45934756\|gb\|AAS79430.1\| phospholipase A2 [Sistrurus catenatus tergeminus], gi\|166012678\|gb\|ABY779...	168.0	[0..1]	[146..1]
gi\|76676926 - gi\|76676926\|ref\|XP_582666.2\| PREDICTED: similar to Group IIE secretory phospholipase A2 precursor (P...	168.0	[0..13]	[146..304]
PA23_ECHCO - Phospholipase A2 EC3 OS=Echis coloratus PE=3 SV=1	167.0	[0..1]	[146..1]
PA2BW_PROFL - Basic phospholipase A2 PL-X' OS=Protobothrops flavoviridis PE=2 SV=1	167.0	[0..1]	[146..1]
PA2AD_CROOA - Acidic phospholipase A2 CoaPLA2 OS=Crotalus oreganus abyssus PE=1 SV=1 PA2AD_CROVV - Acidic phospholipase A2 Cvv-E6d OS=Crotalus viridis viridis PE=1 SV=1	167.0	[0..1]	[146..1]
PA2BB_GLOHA - Basic phospholipase A2 B OS=Gloydius halys PE=1 SV=2	166.0	[0..1]	[146..1]
PA2N2_VIPAA - Neutral phospholipase A2 ammodytin I2 OS=Vipera ammodytes ammodytes PE=1 SV=2 gi\|50874406 - gi\|50874406\|emb\|CAE47192.1\| ammodytin I2(A) isoform [Vipera aspis zinnikeri] gi\|50874456, gi\|... - gi\|50874460\|emb\|CAE47219.1\| ammodytin I2(A) isoform [Vipera ammodytes ruffoi], gi\|50874456\|emb\|CAE47... gi\|6967298, gi\|5... - gi\|6967298\|emb\|CAA58840.1\| phospholipase a2 [Vipera ammodytes], gi\|5702036\|emb\|CAA40200.2\| phospholi... gi\|50874454, gi\|... - gi\|50874468\|emb\|CAE47223.1\| ammodytin I2(A) isoform [Vipera aspis aspis], gi\|50874454\|emb\|CAE47216.1... gi\|33187124 - gi\|33187124\|gb\|AAN59984.1\| ammodytin I2 [Vipera aspis] gi\|33187126, gi\|... - gi\|50874462\|emb\|CAE47220.1\| ammodytin I2(A) isoform [Vipera berus berus], gi\|50874418\|emb\|CAE47198.1...	166.0	[0..1]	[146..1]

Back

Predicted Domain #1

Region A:
Residues: [1-146]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVLLLLAVV IMAFGSIQVQ GSLLEFGQMI LFKTGKRADV SYGFYGCHCG VGGRGSPKDA  60
   61 TDWCCVTHDC CYNRLEKRGC GTKFLTYKFS YRGGQISCST NQDSCRKQLC QCDKAAAECF 120
  121 ARNKKSYSLK YQFYPNKFCK GKTPSC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.69897
Match:	1aypA
Description:	Phospholipase A2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phospholipase A2 activity	5.6430968678228	bayes_pls_golite062009
phospholipase activity	5.38445724291842	bayes_pls_golite062009
calcium-dependent phospholipase A2 activity	4.05813159633475	bayes_pls_golite062009
lipase activity	3.51338748073942	bayes_pls_golite062009
cell surface binding	3.03976629465117	bayes_pls_golite062009
carboxylesterase activity	2.68079964970429	bayes_pls_golite062009
receptor binding	2.23831898285432	bayes_pls_golite062009
binding	1.6033670102211	bayes_pls_golite062009
protein binding	1.47445022237761	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.42015803437458	bayes_pls_golite062009
hydrolase activity	1.32355620269997	bayes_pls_golite062009
heparin binding	1.06811660027805	bayes_pls_golite062009
catalytic activity	0.975181414554529	bayes_pls_golite062009
glycosaminoglycan binding	0.453108206649759	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: