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Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate; does not require Ca2+. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate; requires Ca2+. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. Catalysis of the hydrolysis of any ester bond. Catalysis of the hydrolysis of a glycerophospholipid. Catalysis of the hydrolysis of a lipid or phospholipid.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: phospholipase A2 activity
Acc: GO:0004623
Aspect: Molecular Function
Desc: Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate.
Synonyms:
  • phospholipase A
  • cytosolic phospholipase A2 activity
  • phosphatidylcholine 2-acylhydrolase activity
  • lecithinase A activity
  • secreted phospholipase A2 activity
  • phosphatidase activity
  • phosphatidolipase activity
Proteins in PDR annotated with:
   This term: 80 [Search]
   Term or descendants: 94 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004623 - phospholipase A2 activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle