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View Structure Prediction Details

Protein: EXOS1_MOUSE
Organism: Mus musculus
Length: 195 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EXOS1_MOUSE.

Description E-value Query
Range
Subject
Range
gi|59858307, gi|... - gi|62751675|ref|NP_001015529.1| exosomal core protein CSL4 [Bos taurus], gi|59858307|gb|AAX08988.1| ...
185.0 [0..1] [195..1]
gi|149040180, gi... - gi|149040180|gb|EDL94218.1| rCG57589, isoform CRA_a [Rattus norvegicus], gi|149040177|gb|EDL94215.1|...
185.0 [0..1] [195..1]
gi|57107227 - gi|57107227|ref|XP_534981.1| PREDICTED: similar to exosome component 1 isoform 1 [Canis familiaris]
185.0 [0..1] [195..1]
EXOSC1 - exosome component 1
gi|114632191 - gi|114632191|ref|XP_507960.2| PREDICTED: similar to CGI-108 protein [Pan troglodytes]
CCDS7459.1_1 - null
gi|208966238 - gi|208966238|dbj|BAG73133.1| exosome component 1 [synthetic construct]
gi|109090153 - gi|109090153|ref|XP_001103710.1| PREDICTED: exosome component 1 [Macaca mulatta]
183.0 [0..1] [195..1]
gi|220678445, gi... - gi|68353788|ref|XP_687222.1| PREDICTED: similar to CGI-108 protein [Danio rerio], gi|224495967|ref|N...
166.0 [0..1] [194..1]
gi|50415689, gi|... - gi|50415689|gb|AAH77633.1| MGC86284 protein [Xenopus laevis], gi|148225176|ref|NP_001086901.1| MGC86...
165.0 [0..3] [195..2]

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Predicted Domain #1
Region A:
Residues: [1-195]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPPVRYCIP GERLCNLEEG SPGSGTYTRH GYIFSSLAGC LMKTSENGAV PVVSVMRETE  60
   61 SQLLPDVGAV VTCKVSSINS RFAKVHILYV GSTPLKNAFR GTIRKEDIRA TEKDKVEIYK 120
  121 SFRPGDIVLA KVISLGDAQS NYLLTTAENE LGVVVAHSES GVQMVPISWC EMQCPKTHTK 180
  181 EFRKVARVQP EFLQT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.69897
Match: 2nn6I
Description: No description for 2nn6I was found.

Predicted functions:

Term Confidence Notes
ribonuclease activity 7.42330864261751 bayes_pls_golite062009
exoribonuclease activity 6.76241588209982 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 6.73428326869965 bayes_pls_golite062009
3'-5'-exoribonuclease activity 5.13367897180134 bayes_pls_golite062009
structural constituent of ribosome 4.51084463039261 bayes_pls_golite062009
structural molecule activity 4.29692945022158 bayes_pls_golite062009
3'-5' exonuclease activity 3.51306349336452 bayes_pls_golite062009
nucleic acid binding 3.194200758646 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3.07263153665399 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.73968547121328 bayes_pls_golite062009
DNA binding 2.71213098011194 bayes_pls_golite062009
exonuclease activity 2.66053639652924 bayes_pls_golite062009
binding 2.63617204791771 bayes_pls_golite062009
RNA binding 2.41160981373213 bayes_pls_golite062009
structure-specific DNA binding 1.81524862921454 bayes_pls_golite062009
single-stranded DNA binding 1.62996999055328 bayes_pls_golite062009
1.5765009871268 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 1.35850109411274 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 1.35845277283398 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 1.35845277283398 bayes_pls_golite062009
exoribonuclease II activity 1.18248519339188 bayes_pls_golite062009
transcription regulator activity 0.996884322431837 bayes_pls_golite062009
hydrolase activity 0.724860465280978 bayes_pls_golite062009
nuclease activity 0.57381531077345 bayes_pls_golite062009
mRNA binding 0.4162128308402 bayes_pls_golite062009
ligase activity 0.346041081217685 bayes_pls_golite062009
sequence-specific DNA binding 0.32084431704638 bayes_pls_golite062009
transcription factor activity 0.298729064067577 bayes_pls_golite062009
translation regulator activity 0.22908707234671 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.179682348023561 bayes_pls_golite062009
catalytic activity 0.161830442565647 bayes_pls_golite062009
aspartate-tRNA ligase activity 0.151650064901878 bayes_pls_golite062009
telomeric DNA binding 0.150235510823939 bayes_pls_golite062009
translation initiation factor activity 0.11625379846973 bayes_pls_golite062009
RNA polymerase activity 0.0740938021136293 bayes_pls_golite062009
DNA-directed RNA polymerase activity 0.0740938021136293 bayes_pls_golite062009
protein binding 0.0528188351789111 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle