YRC Public Data Repository - Protein Structure Prediction

Protein:	SLD5_MOUSE
Organism:	Mus musculus
Length:	223 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SLD5_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|76655942 - gi\|76655942\|ref\|XP_874005.1\| PREDICTED: similar to SLD5 [Bos taurus]	329.0	[0..1]	[223..267]
SLD5_RAT - DNA replication complex GINS protein SLD5 OS=Rattus norvegicus GN=Gins4 PE=1 SV=1	310.0	[0..1]	[223..1]
gi\|73979207 - gi\|73979207\|ref\|XP_539958.2\| PREDICTED: similar to SLD5 [Canis familiaris]	308.0	[0..1]	[223..69]
GINS4 - GINS complex subunit 4 (Sld5 homolog)	307.0	[0..1]	[223..1]
gi\|114619902 - gi\|114619902\|ref\|XP_001138293.1\| PREDICTED: SLD5 [Pan troglodytes]	307.0	[0..1]	[223..1]
gi\|109086239 - gi\|109086239\|ref\|XP_001094432.1\| PREDICTED: similar to SLD5 [Macaca mulatta]	305.0	[0..1]	[223..1]
gi\|46249482, gi\|... - gi\|46249482\|gb\|AAH68670.1\| MGC81062 protein [Xenopus laevis], gi\|29365477\|dbj\|BAC66457.1\| Sld5 [Xeno...	283.0	[0..1]	[223..1]
gi\|58332332, gi\|... - gi\|58332332\|ref\|NP_001011045.1\| hypothetical LOC496455 [Xenopus (Silurana) tropicalis], gi\|54038183\|...	281.0	[0..1]	[223..1]
gi\|125825005, gi... - gi\|57525923\|ref\|NP_001003546.1\| hypothetical protein LOC445152 [Danio rerio], gi\|50418488\|gb\|AAH7824...	255.0	[0..22]	[223..2]
gi\|157766456 - gi\|157766456\|ref\|XP_001675571.1\| Hypothetical protein CBG12913 [Caenorhabditis briggsae AF16] gi\|187029084, gi... - gi\|39595922\|emb\|CAE67425.1\| Hypothetical protein CBG12913 [Caenorhabditis briggsae], gi\|187029084\|em...	241.0	[0..5]	[223..1]

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Predicted Domain #1

Region A:
Residues: [1-223]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEVLDLHGQ DSDGGSEEMV LTPAELIEKL EQAWMNEKFA PELLESKAEI VECVMEQLEH  60
   61 MEENLRRAKK GDLKVSIHRM EMERIRYVLS SYLRCRLMKI EKFFPHILEK EKVRSEGEPS 120
  121 SLSPEEFVFA KEYMDHTETH FKNVALKHMP PNLQKVDLLR AVPKPDLDSY VFLRVKERQE 180
  181 NILVEPEADE QRDYVIDLEV GSQHLIRYKT IAPLVASGAV QLI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	83.69897
Match:	2e9xD
Description:	No description for 2e9xD was found.

Predicted functions:

Term	Confidence	Notes
3'-5' DNA helicase activity	3.30007058745861	bayes_pls_golite062009
DNA helicase activity	2.7662250039458	bayes_pls_golite062009
binding	1.86366637427031	bayes_pls_golite062009
protein binding	1.52285169518311	bayes_pls_golite062009
transcription regulator activity	1.2336233528067	bayes_pls_golite062009
helicase activity	1.2110072302388	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.406116199163083	bayes_pls_golite062009
pyrophosphatase activity	0.350000641617868	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.33576520693158	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.333445385039412	bayes_pls_golite062009
catalytic activity	0.161911144249814	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: