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View Structure Prediction Details

Protein: gi|3694661
Organism: Homo sapiens
Length: 391 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|3694661.

Description E-value Query
Range
Subject
Range
gi|6841066 - gi|6841066|gb|AAF28888.1|AF123303_1 calcium-binding transporter [Homo sapiens]
2.0E-63 [164..391] [178..407]
gi|109012620 - gi|109012620|ref|XP_001083575.1| PREDICTED: similar to solute carrier family 25 member 24 isoform 1 ...
2.0E-63 [164..391] [185..414]
gi|114558229 - gi|114558229|ref|XP_514375.2| PREDICTED: solute carrier family 25 member 24 [Pan troglodytes]
1.0E-62 [164..391] [381..610]
gi|73959965 - gi|73959965|ref|XP_854738.1| PREDICTED: similar to solute carrier family 25 member 24 isoform 2 [Can...
2.0E-61 [164..391] [175..404]

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Predicted Domain #1
Region A:
Residues: [1-165]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIVRLSVHA KWIMGKVTGT KMQKTAKVRV IRLVLDPHLL KYYNKQKTYF AHNALQQCTI  60
   61 GDIVLLKALP VPRTKHVKHE LAEIVFKVGK LVDPVTGKPC AGTTYLESPL SSETTQGVDG 120
  121 ASRPSRGPAP CRAGPGARHL RPWPESPRPE PRGLPGPGRG SMATW

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.09691
Match: 1j5eQ
Description: Ribosomal protein S17
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural constituent of ribosome 7.45319063235379 bayes_pls_golite062009
structural molecule activity 6.87843523680097 bayes_pls_golite062009
nucleic acid binding 2.69275272183315 bayes_pls_golite062009
DNA binding 1.97161900822354 bayes_pls_golite062009
binding 1.81248034004657 bayes_pls_golite062009
RNA binding 1.76502371106766 bayes_pls_golite062009
translation regulator activity 1.46320772716954 bayes_pls_golite062009
translation factor activity, nucleic acid binding 1.40718318783582 bayes_pls_golite062009
translation initiation factor activity 1.27539679024898 bayes_pls_golite062009
structure-specific DNA binding 0.83151863389272 bayes_pls_golite062009
single-stranded DNA binding 0.72238927168323 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 0.474251377131502 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 0.47336621289748 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 0.47336621289748 bayes_pls_golite062009
transcription regulator activity 0.157816897728538 bayes_pls_golite062009
DNA-directed RNA polymerase activity 0.1542034177713 bayes_pls_golite062009
RNA polymerase activity 0.1542034177713 bayes_pls_golite062009
ribonuclease activity 0.0760793505650201 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [166-391]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RRDGRLTGGQ RLLCAGLAGT LSLSLTAPLE LATVLAQVGV VRGHARGPWA TGHRVWRAEG  60
   61 LRALWKGNAV ACLRLFPCSA VQLAAYRKFV VLFTDDLGHI SQWSSIMAGS LAGMVSTIVT 120
  121 YPTDLIKTRL IMQNILEPSY RGLLHAFSTI YQQEGFLALY RGVSLTVVGA LPFSAGSLLV 180
  181 YMNLEKIWNG PRDQFSLPQN FANVCLAAAV TQTLSFPFET VKRKMQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.69897
Match: 1okcA
Description: structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle