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View Structure Prediction Details

Protein: BUB3
Organism: Saccharomyces cerevisiae
Length: 341 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BUB3.

Description E-value Query
Range
Subject
Range
gi|17225206 - gi|17225206|gb|AAL37299.1|AF323583_1 beta transducin-like protein HET-E2C*4 [Podospora anserina]
0.0 [3..341] [917..1230]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
9.0E-97 [2..341] [1149..1463]

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Predicted Domain #1
Region A:
Residues: [1-341]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQIVQIEQAP KDYISDIKII PSKSLLLITS WDGSLTVYKF DIQAKNVDLL QSLRYKHPLL  60
   61 CCNFIDNTDL QIYVGTVQGE ILKVDLIGSP SFQALTNNEA NLGICRICKY GDDKLIAASW 120
  121 DGLIEVIDPR NYGDGVIAVK NLNSNNTKVK NKIFTMDTNS SRLIVGMNNS QVQWFRLPLC 180
  181 EDDNGTIEES GLKYQIRDVA LLPKEQEGYA CSSIDGRVAV EFFDDQGDDY NSSKRFAFRC 240
  241 HRLNLKDTNL AYPVNSIEFS PRHKFLYTAG SDGIISCWNL QTRKKIKNFA KFNEDSVVKI 300
  301 ACSDNILCLA TSDDTFKTNA AIDQTIELNA SSIYIIFDYE N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.154902
Match: 1b9xA_
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
dynein binding 3.17817581100892 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
cytoskeletal protein binding 2.10036013463576 bayes_pls_golite062009
transcription repressor activity 1.6725482369574 bayes_pls_golite062009
nucleic acid binding 1.63776917287392 bayes_pls_golite062009
ubiquitin-protein ligase activity 1.59258100795958 bayes_pls_golite062009
transcription regulator activity 1.56901113625383 bayes_pls_golite062009
small conjugating protein ligase activity 1.48624129577934 bayes_pls_golite062009
actin binding 1.40831746593132 bayes_pls_golite062009
protein binding 1.21879977456466 bayes_pls_golite062009
DNA binding 1.0776875611211 bayes_pls_golite062009
tubulin binding 1.07196649995443 bayes_pls_golite062009
microtubule binding 1.04245147316521 bayes_pls_golite062009
transcription corepressor activity 0.963909191437161 bayes_pls_golite062009
transcription factor activity 0.541665384827041 bayes_pls_golite062009
acid-amino acid ligase activity 0.535041400676017 bayes_pls_golite062009
transporter activity 0.284701931503833 bayes_pls_golite062009
structural molecule activity 0.254012051644049 bayes_pls_golite062009
transcription factor binding 0.244641056034795 bayes_pls_golite062009
hydrolase activity 0.181211933860468 bayes_pls_golite062009
histone binding 0.166694897714113 bayes_pls_golite062009
0.0248988265652406 bayes_pls_golite062009
transcription cofactor activity 0.0160791658499004 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle