Protein: | SIN3 |
Organism: | Saccharomyces cerevisiae |
Length: | 1536 amino acids |
Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SIN3.
Description | E-value | Query Range |
Subject Range |
|
0.0 | [1..1536] | [1..1538] |
|
0.0 | [87..1489] | [28..1363] |
|
0.0 | [378..1362] | [4..954] |
|
0.0 | [387..1481] | [15..1063] |
|
0.0 | [292..1030] | [5..833] |
Region A: Residues: [1-237] |
1 11 21 31 41 51 | | | | | | 1 MSQVWHNSNS QSNDVATSND ATGSNERNEK EPSLQGNKPG FVQQQQRITL PSLSALSTKE 60 61 EDRRDSNGQQ ALTSHAAHIL GYPPPHSNAM PSIATDSALK QPHEYHPRPK SSSSSPSINA 120 121 SLMNAGPAPL PTVGAASFSL SRFDNPLPIK APVHTEEPKS YNGLQEEEKA TQRPQDCKEV 180 181 PAGVQPADAP DPSSNHADAN DDNNNNENSH DEDADYRPLN VKDALSYLEQ VKFQFSS |
Detection Method: | |
Confidence: | 11.5 |
Match: | 1k83A |
Description: | RBP1 |
Matching Structure (courtesy of the PDB): |
Region A: Residues: [238-321] |
1 11 21 31 41 51 | | | | | | 1 RPDIYNLFLD IMKDFKSQAI DTPGVIERVS TLFRGYPILI QGFNTFLPQG YRIECSSNPD 60 61 DPIRVTTPMG TTTVNNNISP SGRG |
Detection Method: | |
Confidence: | 19.346787 |
Match: | PF02671 |
Description: | Paired amphipathic helix repeat |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Term | Confidence | Notes |
protein deacetylase activity | 8.92489148049718 | bayes_pls_golite062009 |
histone deacetylase activity | 8.77562367748348 | bayes_pls_golite062009 |
deacetylase activity | 7.74805102638387 | bayes_pls_golite062009 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 5.99241841178307 | bayes_pls_golite062009 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | 4.85992273034906 | bayes_pls_golite062009 |
transcription repressor activity | 4.25514230798992 | bayes_pls_golite062009 |
transcription regulator activity | 3.82193713323077 | bayes_pls_golite062009 |
transcription corepressor activity | 3.30769773581294 | bayes_pls_golite062009 |
nucleic acid binding | 2.83214064778422 | bayes_pls_golite062009 |
DNA binding | 2.82083682611814 | bayes_pls_golite062009 |
transcription factor binding | 2.73494763175272 | bayes_pls_golite062009 |
transcription cofactor activity | 2.59356984380124 | bayes_pls_golite062009 |
binding | 2.59005615358803 | bayes_pls_golite062009 |
protein binding | 2.41769888237582 | bayes_pls_golite062009 |
transcription factor activity | 1.99794029160509 | bayes_pls_golite062009 |
transcription activator activity | 1.89949115818087 | bayes_pls_golite062009 |
RNA polymerase II transcription factor activity | 1.41949477529902 | bayes_pls_golite062009 |
transcription coactivator activity | 0.918453145717461 | bayes_pls_golite062009 |
catalytic activity | 0.30211814650972 | bayes_pls_golite062009 |
Region A: Residues: [322-423] |
1 11 21 31 41 51 | | | | | | 1 TTDAQELGSF PESDGNGVQQ PSNVPMVPSS VYQSEQNQDQ QQSLPLLATS SGLPSIQQPE 60 61 MPAHRQIPQS QSLVPQEDAK KNVDVEFSQA ISYVNKIKTR FA |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Region A: Residues: [424-489] |
1 11 21 31 41 51 | | | | | | 1 DQPDIYKHFL EILQTYQREQ KPINEVYAQV THLFQNAPDL LEDFKKFLPD SSASANQQVQ 60 61 HAQQHA |
Detection Method: | |
Confidence: | 19.69897 |
Match: | PF02671 |
Description: | Paired amphipathic helix repeat |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Region A: Residues: [490-606] |
1 11 21 31 41 51 | | | | | | 1 QQQHEAQMHA QAQAQAQAQA QVEQQKQQQQ FLYPASGYYG HPSNRGIPQQ NLPPIGSFSP 60 61 PTNGSTVHEA YQDQQHMQPP HFMPLPSIVQ HGPNMVHQGI ANENPPLSDL RTSLTEQ |
Detection Method: | |
Confidence: | 172.134302 |
Match: | 1g1eB_ |
Description: | Sin3A |
Matching Structure (courtesy of the PDB): |
Term | Confidence | Notes |
protein deacetylase activity | 9.15317765173842 | bayes_pls_golite062009 |
histone deacetylase activity | 9.00540919224423 | bayes_pls_golite062009 |
deacetylase activity | 7.91874136549804 | bayes_pls_golite062009 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 6.08470985892139 | bayes_pls_golite062009 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | 4.91057345050982 | bayes_pls_golite062009 |
transcription repressor activity | 4.58162229232685 | bayes_pls_golite062009 |
transcription regulator activity | 3.97924147512738 | bayes_pls_golite062009 |
transcription corepressor activity | 3.71696410617503 | bayes_pls_golite062009 |
transcription factor binding | 3.06004981994503 | bayes_pls_golite062009 |
transcription cofactor activity | 2.96293930027313 | bayes_pls_golite062009 |
DNA binding | 2.90699688513784 | bayes_pls_golite062009 |
nucleic acid binding | 2.89854237920034 | bayes_pls_golite062009 |
binding | 2.65480555250736 | bayes_pls_golite062009 |
protein binding | 2.51615225301602 | bayes_pls_golite062009 |
transcription factor activity | 2.07660852403223 | bayes_pls_golite062009 |
transcription activator activity | 1.96507140095887 | bayes_pls_golite062009 |
RNA polymerase II transcription factor activity | 1.50631346254518 | bayes_pls_golite062009 |
transcription coactivator activity | 1.06494495723884 | bayes_pls_golite062009 |
catalytic activity | 0.289349813503192 | bayes_pls_golite062009 |
Region A: Residues: [607-732] |
1 11 21 31 41 51 | | | | | | 1 YAPSSIQHQQ QHPQSISPIA NTQYGDIPVR PEIDLDPSIV PVVPEPTEPI ENNISLNEEV 60 61 TFFEKAKRYI GNKHLYTEFL KILNLYSQDI LDLDDLVEKV DFYLGSNKEL FTWFKNFVGY 120 121 QEKTKC |
Detection Method: | |
Confidence: | 11.33 |
Match: | 1g1eB |
Description: | Sin3A |
Matching Structure (courtesy of the PDB): |
Term | Confidence | Notes |
protein deacetylase activity | 8.92489148049718 | bayes_pls_golite062009 |
histone deacetylase activity | 8.77562367748348 | bayes_pls_golite062009 |
deacetylase activity | 7.74805102638387 | bayes_pls_golite062009 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 5.99241841178307 | bayes_pls_golite062009 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | 4.85992273034906 | bayes_pls_golite062009 |
transcription repressor activity | 4.25514230798992 | bayes_pls_golite062009 |
transcription regulator activity | 3.82193713323077 | bayes_pls_golite062009 |
transcription corepressor activity | 3.30769773581294 | bayes_pls_golite062009 |
nucleic acid binding | 2.83214064778422 | bayes_pls_golite062009 |
DNA binding | 2.82083682611814 | bayes_pls_golite062009 |
transcription factor binding | 2.73494763175272 | bayes_pls_golite062009 |
transcription cofactor activity | 2.59356984380124 | bayes_pls_golite062009 |
binding | 2.59005615358803 | bayes_pls_golite062009 |
protein binding | 2.41769888237582 | bayes_pls_golite062009 |
transcription factor activity | 1.99794029160509 | bayes_pls_golite062009 |
transcription activator activity | 1.89949115818087 | bayes_pls_golite062009 |
RNA polymerase II transcription factor activity | 1.41949477529902 | bayes_pls_golite062009 |
transcription coactivator activity | 0.918453145717461 | bayes_pls_golite062009 |
catalytic activity | 0.30211814650972 | bayes_pls_golite062009 |
Region A: Residues: [733-1024] |
1 11 21 31 41 51 | | | | | | 1 IENIVHEKHR LDLDLCEAFG PSYKRLPKSD TFMPCSGRDD MCWEVLNDEW VGHPVWASED 60 61 SGFIAHRKNQ YEETLFKIEE ERHEYDFYIE SNLRTIQCLE TIVNKIENMT ENEKANFKLP 120 121 PGLGHTSMTI YKKVIRKVYD KERGFEIIDA LHEHPAVTAP VVLKRLKQKD EEWRRAQREW 180 181 NKVWRELEQK VFFKSLDHLG LTFKQADKKL LTTKQLISEI SSIKVDQTNK KIHWLTPKPK 240 241 SQLDFDFPDK NIFYDILCLA DTFITHTTAY SNPDKERLKD LLKYFISLFF SI |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Region A: Residues: [1025-1368] |
1 11 21 31 41 51 | | | | | | 1 SFEKIEESLY SHKQNVSESS GSDDGSSIAS RKRPYQQEMS LLDILHRSRY QKLKRSNDED 60 61 GKVPQLSEPP EEEPNTIEEE ELIDEEAKNP WLTGNLVEEA NSQGIIQNRS IFNLFANTNI 120 121 YIFFRHWTTI YERLLEIKQM NERVTKEINT RSTVTFAKDL DLLSSQLSEM GLDFVGEDAY 180 181 KQVLRLSRRL INGDLEHQWF EESLRQAYNN KAFKLYTIDK VTQSLVKHAH TLMTDAKTAE 240 241 IMALFVKDRN ASTTSAKDQI IYRLQVRSHM SNTENMFRIE FDKRTLHVSI QYIALDDLTL 300 301 KEPKADEDKW KYYVTSYALP HPTEGIPHEK LKIPFLERLI EFGQ |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Region A: Residues: [1369-1536] |
1 11 21 31 41 51 | | | | | | 1 DIDGTEVDEE FSPEGISVST LKIKIQPITY QLHIENGSYD VFTRKATNKY PTIANDNTQK 60 61 GMVSQKKELI SKFLDCAVGL RNNLDEAQKL SMQKKWENLK DSIAKTSAGN QGIESETEKG 120 121 KITKQEQSDN LDSSTASVLP ASITTVPQDD NIETTGNTES SDKGAKIQ |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Region A: Residues: [1179-1355] |
1 11 21 31 41 51 | | | | | | 1 TFAKDLDLLS SQLSEMGLDF VGEDAYKQVL RLSRRLINGD LEHQWFEESL RQAYNNKAFK 60 61 LYTIDKVTQS LVKHAHTLMT DAKTAEIMAL FVKDRNASTT SAKDQIIYRL QVRSHMSNTE 120 121 NMFRIEFDKR TLHVSIQYIA LDDLTLKEPK ADEDKWKYYV TSYALPHPTE GIPHEKL |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Region A: Residues: [1356-1449] |
1 11 21 31 41 51 | | | | | | 1 KIPFLERLIE FGQDIDGTEV DEEFSPEGIS VSTLKIKIQP ITYQLHIENG SYDVFTRKAT 60 61 NKYPTIANDN TQKGMVSQKK ELISKFLDCA VGLR |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Region A: Residues: [1450-1536] |
1 11 21 31 41 51 | | | | | | 1 NNLDEAQKLS MQKKWENLKD SIAKTSAGNQ GIESETEKGK ITKQEQSDNL DSSTASVLPA 60 61 SITTVPQDDN IETTGNTESS DKGAKIQ |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.