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Protein Overview: pst2

General Information:
Name(s) found: pst2 / SPAC23C11.15 [Sanger Pombe]
Description(s) found:
Found 16 descriptions.
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  • Clr6 histone deacetylase complex subunit Pst2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 1075 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    Rpd3S complex [IDALink to PubMed articleLink to PubMed article]
    Biological Process: chromatin remodeling [ICLink to PubMed article]
    chromosome condensation [IMPLink to PubMed article]
    chromatin silencing [ISSLink to PubMed article]
    histone deacetylation [IMPLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    transcription corepressor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQTLAILKN DNSTLVAEMQ NQLVHDFSPN GTALPELDIK AFVQKLGQRL CHRPYVYSAF  60
   61 MDVVKALHNE IVDFPGFIER ISVILRDYPD LLEYLNIFLP SSYKYLLSNS GANFTLQFTT 120
  121 PSGPVSTPST YVATYNDLPC TYHRAIGFVS RVRRALLSNP EQFFKLQDSL RKFKNSECSL 180
  181 SELQTIVTSL LAEHPSLAHE FHNFLPSSIF FGSKPPLGSF PLRGIQSSQF TLSNISDLLS 240
  241 QSRPDNLSPF SHLSNESSDF FKNVKNVLTD VETYHEFLKL LNLYVQGIID RNILVSRGFG 300
  301 FLKSNSGLWR SFLSLTSLSP EEFLSVYNSA CSDFPECGPS YRLLPVEERN ISCSGRDDFA 360
  361 WGILNDDWVS HPTWASEESG FIVQRKTPYE EAMTKLEEER YEFDRHIEAT SWTIKSLKKI 420
  421 QNRINELPEE ERETYTLEEG LGLPSKSIYK KTIKLVYTSE HAEEMFKALE RMPCLTLPLV 480
  481 ISRLEEKNEE WKSVKRSLQP GWRSIEFKNY DKSLDSQCVY FKARDKKNVS SKFLLAEADI 540
  541 LRSQAKLHFP LRSRSAFEFS FVYDNEIVLF DTCYMVCTYI VCNSPSGLKK VEHFFKNILP 600
  601 LHFGLEKDKF SIFLDQVFRG PDYDVNAPNI VGNKPVRRKR SNSITQLTEF VKQPKINGQR 660
  661 ESRSAAAARK KEESGNKSQS NSQNSLSDES GNVTPVSKKQ LSQPAAAIKA SLKYPSHPDS 720
  721 LLEHQDHAGD TENEMHDDVD KEQFGYSSMY VFFRLFNLLY ERLYELQRLE DQVSIIQQRI 780
  781 IPNPVSQKQK IWRDRWNDLS DVPDEKTHYE NTYVMILRLI YGIVDQSAFE DYLRFYYGNK 840
  841 AYKIYTIDKL VWSAAKQVHH IVSDGKYKFV TSLVEQNSSA SPKKNYDDFL YRLEIEKLLN 900
  901 PDEILFRFCW INKFKSFGIK IMKRANLIVD QSLDTQRRVW KKYVQNYRIQ KLTEEISYKN 960
  961 YRCPFLCRNI EKERTVEQLV SRLQTKLLRS AELVSGLQAK LCLDSFKLLY LPRTEDSYID1020
 1021 ASYLRLRDTD FLDCQNKRKQ RWRNRWESLL KSVRGTSDNT AEVNFDADIN ALFIP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..108] PSI-BLAST 29.0 Solution structure of the NRSF/REST-mSin3B PAH1 complex
    2 View Details [109..222] PSI-BLAST 18.39794 No description for 2f05A was found.
    3 View Details [223..318] FFAS03 2.81 Solution structure of the first PAH domain of the mouse transcriptional repressor SIN3B
    4 View Details [319..442] Pfam 64.585027 No description for PF08295.3 was found. No confident structure predictions are available.
    5 View Details [443..703] deduced N/A No confident structure predictions are available.
    6 View Details [704..797] deduced N/A No confident structure predictions are available.
    7 View Details [798..932] MSA 1.033995 View MSA. No confident structure predictions are available.
    8 View Details [933..1075] MSA 2.032988 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • protein deacetylase activity
    		•  9.15317765173842 bayes_pls_golite062009
  • histone deacetylase activity
    		•  9.00540919224423 bayes_pls_golite062009
  • deacetylase activity
    		•  7.91874136549804 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
    		•  6.08470985892139 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  4.91057345050982 bayes_pls_golite062009
  • transcription repressor activity
    		•  4.58162229232685 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.97924147512738 bayes_pls_golite062009
  • transcription corepressor activity
    		•  3.71696410617503 bayes_pls_golite062009
  • transcription factor binding
    		•  3.06004981994503 bayes_pls_golite062009
  • transcription cofactor activity
    		•  2.96293930027313 bayes_pls_golite062009
  • DNA binding
    		•  2.90699688513784 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.89854237920034 bayes_pls_golite062009
  • binding
    		•  2.65480555250736 bayes_pls_golite062009
  • transcription factor activity
    		•  2.07660852403223 bayes_pls_golite062009
  • protein binding
    		•  1.46569798429756 bayes_pls_golite062009
  • transcription coactivator activity
    		•  1.06494495723884 bayes_pls_golite062009
  • transcription activator activity
    		•  0.63586266373929 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.599183685811182 bayes_pls_golite062009
  • catalytic activity
    		•  0.289349813503192 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle