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View Structure Prediction Details

Protein: OCA1
Organism: Saccharomyces cerevisiae
Length: 238 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OCA1.

Description E-value Query
Range		 Subject
Range
OCA1_YEAS7 - Putative tyrosine-protein phosphatase OCA1 OS=Saccharomyces cerevisiae (strain YJM789) GN=OCA1 PE=3 ...
gi|207341726 - gi|207341726|gb|EDZ69703.1| YNL099Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190409088 - gi|190409088|gb|EDV12353.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
OCA1 - Putative protein tyrosine phosphatase, required for cell cycle arrest in response to oxidative damag...
OCA1_YEAST - Putative tyrosine-protein phosphatase OCA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) ...
 1.0E-54 [1..238] [1..238]
DUSP7 - dual specificity phosphatase 7
 3.0E-43 [6..221] [76..288]
tr|G3H889|G3H889... - Dual specificity protein phosphatase OS=Cricetulus griseus GN=I79_006589 PE=3 SV=1
DUS7_MOUSE - (Q91Z46) Dual specificity protein phosphatase 7 (EC 3.1.3.48) (EC 3.1.3.16)
 3.0E-43 [6..221] [74..286]
DUS7_RAT - Dual specificity protein phosphatase 7 (Fragment) OS=Rattus norvegicus GN=Dusp7 PE=2 SV=1
 4.0E-43 [6..221] [34..246]
Y1500_ARATH - Probable tyrosine-protein phosphatase At1g05000 OS=Arabidopsis thaliana GN=At1g05000 PE=1 SV=1
 1.0E-40 [31..220] [6..201]
gi|38322721, gi|... - gi|38322721|gb|AAR16274.1| dual specificity phosphatase 6 [Takifugu rubripes], gi|17488591|gb|AAL403...
 9.0E-38 [6..221] [135..347]
gi|37747710, gi|... - gi|37747710|gb|AAH59985.1| MGC68682 protein [Xenopus laevis], gi|147901514|ref|NP_001083256.1| MAP k...
 3.0E-37 [6..221] [133..344]

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Predicted Domain #1
Region A:
Residues: [1-238] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSKVGEYED VPEDESRLTE ENVSVPEEEV EDEDEEEDDD DDHIYINEET ESGREKVLVS  60
   61 HAPQERIVPP LNFCPVERYL YRSGQPSPVN FPFLLNLKLK TIIWLSNEEP QDTLLEFCDT 120
  121 HRINLQFAAI NPDAGEDDNP WDGLTEHSII NVLQTIVTQE NYPLLVCCGM GRHRTGTVIG 180
  181 CLRRIMGWNL ASVSEEYRRF TGSRGGRILV ELLIEAFDTN LVKIDKNKAP SWLLTALE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.69897
Match: 1vhrA_
Description: VH1-related dual-specificity phosphatase, VHR
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphoprotein phosphatase activity 7.30669036331612 bayes_pls_golite062009
phosphatase activity 6.6585143972081 bayes_pls_golite062009
phosphoric ester hydrolase activity 6.44546424348532 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 5.56007278295923 bayes_pls_golite062009
protein tyrosine phosphatase activity 5.3097342170423 bayes_pls_golite062009
hydrolase activity 4.08088661270715 bayes_pls_golite062009
transmembrane receptor protein phosphatase activity 2.94635032478625 bayes_pls_golite062009
transmembrane receptor protein tyrosine phosphatase activity 2.94635032478625 bayes_pls_golite062009
protein tyrosine/serine/threonine phosphatase activity 2.77531895423367 bayes_pls_golite062009
protein serine/threonine phosphatase activity 1.95004535887255 bayes_pls_golite062009
binding 1.42026750513729 bayes_pls_golite062009
inositol or phosphatidylinositol phosphatase activity 1.1200449509328 bayes_pls_golite062009
protein binding 1.07441758584517 bayes_pls_golite062009
catalytic activity 1.06283028154109 bayes_pls_golite062009
lipid phosphatase activity 1.05085928819585 bayes_pls_golite062009
nucleic acid binding 0.778925490811536 bayes_pls_golite062009
DNA binding 0.744259483210066 bayes_pls_golite062009
non-membrane spanning protein tyrosine phosphatase activity 0.724257798127697 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.0776644624761281 bayes_pls_golite062009
kinase activity 0.0715870881653981 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle