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View Structure Prediction Details

Protein: MSS1
Organism: Saccharomyces cerevisiae
Length: 526 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MSS1.

Description E-value Query
Range
Subject
Range
MSS1_YEAST - tRNA modification GTPase MSS1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...
MSS1 - Mitochondrial protein, forms a heterodimer complex with Mto1p that performs the 5-carboxymethylamino...
gi|190408262 - gi|190408262|gb|EDV11527.1| GTPase MSS1, mitochondrial precursor [Saccharomyces cerevisiae RM11-1a]
0.0 [1..526] [1..526]
gi|12721514, gi|... - gi|15603031|ref|NP_246103.1| tRNA modification GTPase TrmE [Pasteurella multocida subsp. multocida s...
0.0 [31..526] [10..465]
gi|254795709, gi... - gi|254795709|ref|YP_003080546.1| 5-methylaminomethyl-2-thiouridine-synthesizing GTPase [Escherichia ...
gi|25319352, gi|... - pir||A98209 hypothetical protein ECs4641 [imported] - Escherichia coli (strain O157:H7, substrain R...
MNME_ECO57 - tRNA modification GTPase MnmE OS=Escherichia coli O157:H7 GN=mnmE PE=3 SV=1
gi|208814185, gi... - gi|208814185|ref|ZP_03255514.1| tRNA modification GTPase TrmE [Escherichia coli O157:H7 str. EC4045]...
gi|208740195, gi... - gi|208820072|ref|ZP_03260392.1| tRNA modification GTPase TrmE [Escherichia coli O157:H7 str. EC4042]...
MNME_ECO5E - tRNA modification GTPase MnmE OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=mnmE PE=3 SV=1
gi|217324903, gi... - gi|217324903|ref|ZP_03440987.1| tRNA modification GTPase TrmE [Escherichia coli O157:H7 str. TW14588...
gi|189373460, gi... - gi|189373460|gb|EDU91876.1| tRNA modification GTPase TrmE [Escherichia coli O157:H7 str. EC869], gi|...
gi|168798745, gi... - gi|189378836|gb|EDU97252.1| tRNA modification GTPase TrmE [Escherichia coli O157:H7 str. EC508], gi|...
gi|195936329 - gi|195936329|ref|ZP_03081711.1| tRNA modification GTPase TrmE [Escherichia coli O157:H7 str. EC4024]
gi|208808040, gi... - gi|208808040|ref|ZP_03250377.1| tRNA modification GTPase TrmE [Escherichia coli O157:H7 str. EC4206]...
gi|189369584, gi... - gi|189369584|gb|EDU88000.1| tRNA modification GTPase TrmE [Escherichia coli O157:H7 str. EC4501], gi...
gi|189364418, gi... - gi|189364418|gb|EDU82837.1| tRNA modification GTPase TrmE [Escherichia coli O157:H7 str. EC4486], gi...
gi|168772255, gi... - gi|187771576|gb|EDU35420.1| tRNA modification GTPase TrmE [Escherichia coli O157:H7 str. EC4196], gi...
gi|168779932, gi... - gi|189002302|gb|EDU71288.1| tRNA modification GTPase TrmE [Escherichia coli O157:H7 str. EC4076], gi...
gi|15833895, gi|... - gi|15833895|ref|NP_312668.1| tRNA modification GTPase TrmE [Escherichia coli O157:H7 str. Sakai], gi...
gi|168748574, gi... - gi|188016998|gb|EDU55120.1| tRNA modification GTPase TrmE [Escherichia coli O157:H7 str. EC4113], gi...
gi|189359120, gi... - gi|189359120|gb|EDU77539.1| tRNA modification GTPase TrmE [Escherichia coli O157:H7 str. EC4401], gi...
0.0 [36..526] [4..454]
MNME_ECOLC - tRNA modification GTPase MnmE OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=mnmE PE=...
MNME_ECO8A - tRNA modification GTPase MnmE OS=Escherichia coli O8 (strain IAI1) GN=mnmE PE=3 SV=1
MNME_ECODH - tRNA modification GTPase MnmE OS=Escherichia coli (strain K12 / DH10B) GN=mnmE PE=3 SV=1
MNME_ECOSE - tRNA modification GTPase MnmE OS=Escherichia coli (strain SE11) GN=mnmE PE=3 SV=1
MNME_ECOBW - tRNA modification GTPase MnmE OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=mnmE PE=3 SV=1
gi|124530079, gi... - gi|124530079|ref|ZP_01700862.1| tRNA modification GTPase TrmE [Escherichia coli B], gi|124499484|gb|...
gi|226838890, gi... - gi|254038925|ref|ZP_04872977.1| tRNA modification GTPase TrmE [Escherichia sp. 1_1_43], gi|226838890...
TRME_ECOLI - Probable tRNA modification GTPase trmE - Escherichia coli
MNME_SHIBS - tRNA modification GTPase MnmE OS=Shigella boydii serotype 4 (strain Sb227) GN=mnmE PE=3 SV=1
gi|89110306, gi|... - gi|89110306|ref|AP_004086.1| GTPase [Escherichia coli str. K-12 substr. W3110], gi|85676337|dbj|BAE7...
EG10997 - tRNA U34 5-methylaminomethyl-2-thiouridine modification GTPase / GTPase required for 5-methylaminome...
MNME_SHIB3 - tRNA modification GTPase MnmE OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=mnmE PE...
gi|188493740, gi... - gi|75514232|ref|ZP_00736540.1| COG0486: Predicted GTPase [Escherichia coli 53638], gi|188493740|ref|...
EG10997 - tRNA U34 5-methylaminomethyl-2-thiouridine modification GTPase / GTPase required for 5-methylaminome...
0.0 [36..526] [4..454]
TRME_PASMU, MNME... - Probable tRNA modification GTPase trmE - Pasteurella multocida, tRNA modification GTPase mnmE OS=Pas...
MNME_PASMU - tRNA modification GTPase MnmE OS=Pasteurella multocida (strain Pm70) GN=mnmE PE=3 SV=1
0.0 [35..526] [1..452]
gi|290554 - gi|290554|gb|AAA62057.1| 50 kD protein
0.0 [36..526] [4..454]
MNME_SALTY - tRNA modification GTPase MnmE OS=Salmonella typhimurium GN=mnmE PE=3 SV=1
TRME_SALTY, MNME... - tRNA modification GTPase trmE - Salmonella typhimurium, tRNA modification GTPase mnmE OS=Salmonella ...
MNME_SALTY - tRNA modification GTPase MnmE OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=mnm...
lcl|NC_016856.1_... - [gene=trmE] [protein=tRNA modification GTPase TrmE] [protein_id=YP_005240111.1] [location=4061906..4...
0.0 [36..526] [4..454]
GTPBP3 - GTP binding protein 3 (mitochondrial)
0.0 [19..526] [18..492]
gi|213052691 - gi|213052691|ref|ZP_03345569.1| tRNA modification GTPase TrmE [Salmonella enterica subsp. enterica s...
gi|213424947 - gi|213424947|ref|ZP_03357697.1| tRNA modification GTPase TrmE [Salmonella enterica subsp. enterica s...
gi|213580794 - gi|213580794|ref|ZP_03362620.1| tRNA modification GTPase TrmE [Salmonella enterica subsp. enterica s...
TRME_SALTI, MNME... - tRNA modification GTPase trmE - Salmonella typhi, tRNA modification GTPase mnmE OS=Salmonella typhi ...
MNME_SALTI - tRNA modification GTPase MnmE OS=Salmonella typhi GN=mnmE PE=3 SV=1
gi|29139607, gi|... - gi|29143971|ref|NP_807313.1| tRNA modification GTPase TrmE [Salmonella enterica subsp. enterica sero...
gi|16762483 - gi|16762483|ref|NP_458100.1| tRNA modification GTPase TrmE [Salmonella enterica subsp. enterica sero...
gi|213865392 - gi|213865392|ref|ZP_03387511.1| tRNA modification GTPase TrmE [Salmonella enterica subsp. enterica s...
0.0 [36..526] [4..454]

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Predicted Domain #1
Region A:
Residues: [1-87]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSASFLQSR LISRSFLVRR SLKRYSGLAK PYTFQQPTIY ALSTPANQTS AIAIIRISGT  60
   61 HAKYIYNRLV DSSTVPPIRK AILRNIY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.900 0.326 GTP binding d.58.12 eEF-1beta-like
View Download 0.917 0.004 mitochondrial inner membrane d.58.5 GlnB-like
View Download 0.772 0.001 mitochondrial inner membrane d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.743 N/A N/A d.214.1 Hypothetical protein MTH1880
View Download 0.726 N/A N/A d.58.5 GlnB-like
View Download 0.666 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.660 N/A N/A d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.658 N/A N/A d.58.14 Ribosomal protein S6
View Download 0.647 N/A N/A d.58.2 Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain
View Download 0.633 N/A N/A b.1.1 Immunoglobulin
View Download 0.623 N/A N/A d.58.12 eEF-1beta-like
View Download 0.600 N/A N/A d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.596 N/A N/A d.58.12 eEF-1beta-like
View Download 0.572 N/A N/A d.214.1 Hypothetical protein MTH1880
View Download 0.565 N/A N/A d.58.12 eEF-1beta-like
View Download 0.522 N/A N/A d.52.1 Alpha-lytic protease prodomain
View Download 0.502 N/A N/A d.89.1 Origin of replication-binding domain, RBD-like
View Download 0.499 N/A N/A d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.489 N/A N/A d.58.12 eEF-1beta-like
View Download 0.464 N/A N/A d.58.12 eEF-1beta-like
View Download 0.462 N/A N/A b.1.1 Immunoglobulin
View Download 0.449 N/A N/A b.84.1 Single hybrid motif
View Download 0.448 N/A N/A d.52.1 Alpha-lytic protease prodomain
View Download 0.435 N/A N/A d.58.8 Viral DNA-binding domain
View Download 0.420 N/A N/A d.58.12 eEF-1beta-like
View Download 0.408 N/A N/A d.74.3 RBP11-like subunits of RNA polymerase
View Download 0.404 N/A N/A d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.403 N/A N/A d.58.13 Anticodon-binding domain of PheRS
View Download 0.401 N/A N/A d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.400 N/A N/A d.130.1 S-adenosylmethionine synthetase
View Download 0.397 N/A N/A d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.397 N/A N/A d.52.7 Ribosome-binding factor A, RbfA
View Download 0.386 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.383 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.381 N/A N/A d.88.1 SRF-like
View Download 0.375 N/A N/A d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.372 N/A N/A d.57.1 DNA damage-inducible protein DinI
View Download 0.370 N/A N/A d.58.17 Metal-binding domain
View Download 0.370 N/A N/A d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.368 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.366 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.365 N/A N/A d.53.1 Ribosomal protein S3 C-terminal domain
View Download 0.350 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.347 N/A N/A d.15.6 Superantigen toxins, C-terminal domain
View Download 0.342 N/A N/A d.58.17 Metal-binding domain
View Download 0.332 N/A N/A d.52.1 Alpha-lytic protease prodomain
View Download 0.319 N/A N/A b.84.2 Rudiment single hybrid motif
View Download 0.315 N/A N/A d.58.23 Probable ACP-binding domain of malonyl-CoA ACP transacylase
View Download 0.315 N/A N/A d.58.42 N-utilization substance G protein NusG, N-terminal domain
View Download 0.314 N/A N/A c.97.1 Cytidine deaminase-like
View Download 0.311 N/A N/A d.58.8 Viral DNA-binding domain
View Download 0.310 N/A N/A d.58.8 Viral DNA-binding domain
View Download 0.308 N/A N/A d.58.10 Acylphosphatase-like
View Download 0.307 N/A N/A d.58.8 Viral DNA-binding domain
View Download 0.306 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.305 N/A N/A d.52.4 YhbC-like, N-terminal domain
View Download 0.301 N/A N/A d.214.1 Hypothetical protein MTH1880
View Download 0.300 N/A N/A d.201.1 SRP19
View Download 0.294 N/A N/A d.58.14 Ribosomal protein S6
View Download 0.294 N/A N/A d.58.17 Metal-binding domain
View Download 0.288 N/A N/A d.74.3 RBP11-like subunits of RNA polymerase
View Download 0.287 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.287 N/A N/A d.15.6 Superantigen toxins, C-terminal domain
View Download 0.287 N/A N/A d.15.6 Superantigen toxins, C-terminal domain
View Download 0.281 N/A N/A d.58.3 Protease propeptides/inhibitors
View Download 0.280 N/A N/A d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.279 N/A N/A d.89.1 Origin of replication-binding domain, RBD-like
View Download 0.271 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.269 N/A N/A d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.267 N/A N/A d.129.1 TATA-box binding protein-like
View Download 0.261 N/A N/A d.214.1 Hypothetical protein MTH1880
View Download 0.258 N/A N/A d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.253 N/A N/A b.107.1 Urease metallochaperone UreE, N-terminal domain
View Download 0.252 N/A N/A d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.251 N/A N/A d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.248 N/A N/A d.58.12 eEF-1beta-like
View Download 0.248 N/A N/A d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.246 N/A N/A a.74.1 Cyclin-like
View Download 0.245 N/A N/A d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.243 N/A N/A d.52.4 YhbC-like, N-terminal domain
View Download 0.238 N/A N/A c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.237 N/A N/A d.58.9 RuBisCO, large subunit, small (N-terminal) domain
View Download 0.234 N/A N/A g.18.1 Complement control module/SCR domain
View Download 0.227 N/A N/A a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.224 N/A N/A d.58.5 GlnB-like
View Download 0.224 N/A N/A d.58.5 GlnB-like
View Download 0.221 N/A N/A d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.220 N/A N/A d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.219 N/A N/A d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.217 N/A N/A d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.215 N/A N/A d.71.1 Cell division protein MinE topological specificity domain
View Download 0.215 N/A N/A d.58.12 eEF-1beta-like
View Download 0.214 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.214 N/A N/A d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.212 N/A N/A d.130.1 S-adenosylmethionine synthetase
View Download 0.212 N/A N/A d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.208 N/A N/A d.105.1 Clathrin adaptor appendage, alpha and beta chain-specific domain
View Download 0.208 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.208 N/A N/A b.1.1 Immunoglobulin
View Download 0.206 N/A N/A d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.204 N/A N/A d.52.4 YhbC-like, N-terminal domain
View Download 0.204 N/A N/A d.58.17 Metal-binding domain
View Download 0.204 N/A N/A d.130.1 S-adenosylmethionine synthetase
View Download 0.203 N/A N/A b.40.4 Nucleic acid-binding proteins
View Download 0.201 N/A N/A d.58.36 Sulfite reductase, domains 1 and 3
View Download 0.200 N/A N/A d.15.6 Superantigen toxins, C-terminal domain

Predicted functions:

Term Confidence Notes
methyltransferase activity 3.28983380541263 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 3.20782575104451 bayes_pls_golite062009
catalytic activity 1.65079399897053 bayes_pls_golite062009
transferase activity 1.3676947912529 bayes_pls_golite062009
coenzyme binding 1.08379167900905 bayes_pls_golite062009
nucleic acid binding 0.913322399315129 bayes_pls_golite062009
structural constituent of ribosome 0.738234102557832 bayes_pls_golite062009
RNA helicase activity 0.73539642422624 bayes_pls_golite062009
RNA-dependent ATPase activity 0.70759024918936 bayes_pls_golite062009
ATP-dependent RNA helicase activity 0.68122080550778 bayes_pls_golite062009
ATP binding 0.60527666756293 bayes_pls_golite062009
binding 0.604868700215668 bayes_pls_golite062009
aminomethyltransferase activity 0.573831999310668 bayes_pls_golite062009
adenyl ribonucleotide binding 0.573214556107072 bayes_pls_golite062009
ligase activity 0.417681194526243 bayes_pls_golite062009
transcription regulator activity 0.390949264169589 bayes_pls_golite062009
DNA binding 0.376487324624615 bayes_pls_golite062009
translation regulator activity 0.29096092258568 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.274994961137851 bayes_pls_golite062009
structural molecule activity 0.0558641287316701 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [88-264]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPSSCSVKPH DQKESKILLD TSLLLYFQAP YSFTGEDVLE LHVHGGKAVV NSILKAIGSL  60
   61 HDRSSGKDIR FALPGDFSRR AFQNGKFDLT QLEGIKDLID SETESQRRSA LSSFNGDNKI 120
  121 LFENWRETII ENMAQLTAII DFADDNSQEI QNTDEIFHNV EKNIICLRDQ IVTFMQK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [265-526]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VEKSTILQNG IKLVLLGAPN VGKSSLVNSL TNDDISIVSD IPGTTRDSID AMINVNGYKV  60
   61 IICDTAGIRE KSSDKIEMLG IDRAKKKSVQ SDLCLFIVDP TDLSKLLPED ILAHLSSKTF 120
  121 GNKRIIIVVN KSDLVSDDEM TKVLNKLQTR LGSKYPILSV SCKTKEGIES LISTLTSNFE 180
  181 SLSQSSADAS PVIVSKRVSE ILKNDVLYGL EEFFKSKDFH NDIVLATENL RYASDGIAKI 240
  241 TGQAIGIEEI LDSVFSKFCI GK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 125.9794
Match: 1egaA_
Description: GTPase Era, N-terminal domain; GTPase Era C-terminal domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle