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View Structure Prediction Details

Protein: YLR243W
Organism: Saccharomyces cerevisiae
Length: 272 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YLR243W.

Description E-value Query
Range		 Subject
Range
gi|207342912 - gi|207342912|gb|EDZ70535.1| YLR243Wp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190405305 - gi|190405305|gb|EDV08572.1| hypothetical protein SCRG_04196 [Saccharomyces cerevisiae RM11-1a]
GPN3_YEAST - GPN-loop GTPase 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GPN3 PE=1 SV=1
YLR243W - Putative protein of unknown function; YLR243W is an essential gene
 2.0E-68 [1..272] [1..272]
gi|14250036, gi|... - gi|21361523|ref|NP_057385.2| GPN-loop GTPase 3 [Homo sapiens], gi|14250036|gb|AAH08416.1| GPN-loop G...
 9.0E-68 [1..270] [1..269]
GPN3_MOUSE - GPN-loop GTPase 3 OS=Mus musculus GN=Gpn3 PE=2 SV=1
 9.0E-68 [1..270] [1..269]
gi|24899793, gi|... - gi|79325073|ref|NP_001031621.1| ATP-binding family protein [Arabidopsis thaliana], gi|30682239|ref|N...
 2.0E-62 [4..261] [3..256]
GPN3_SCHPO - GPN-loop GTPase 3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=fet5 PE=2 SV=1
fet5 - transcription factor Fet5
 2.0E-61 [1..266] [1..266]
gi|115454947, gi... - gi|50918291|ref|XP_469542.1| putative ATP(GTP)-binding protein [Oryza sativa (japonica cultivar-grou...
gi|125545504 - gi|125545504|gb|EAY91643.1| hypothetical protein OsI_012876 [Oryza sativa (indica cultivar-group)]
 7.0E-61 [4..266] [3..278]

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Predicted Domain #1
Region A:
Residues: [1-272] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRVGVMVLG PAGAGKSTFC NSIISHMQTV GRRAHIVNLD PAAEATKYEF TIDIRDLISL  60
   61 DDVMEEMDLG PNGALIYCFE YLLKNLDWLD EEIGDFNDEY LIFDCPGQIE LYTHIPVLPN 120
  121 IVRHLTQQLN FNLCATYLLE APFVIDSSKF FSGALSAMSA MILLELPHIN VLSKLDLIKG 180
  181 DINKKKLKRF LNPDAMLLME TEGMNQASNP KFLRLNQCIA NLVDDFGMVQ FLPLESNNPD 240
  241 SIETILSYVD DITQWAEGQE QKEPNDQIDV EE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.522879
Match: 2ffhA_
Description: Signal sequence recognition protein Ffh; Signal sequence binding protein Ffh; GTPase domain of the signal sequence recognition protein Ffh
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.82708337557815 bayes_pls_golite062009
ion transmembrane transporter activity 2.73258998901465 bayes_pls_golite062009
transporter activity 2.58140740499725 bayes_pls_golite062009
cation transmembrane transporter activity 2.55141814687566 bayes_pls_golite062009
binding 2.44689197844883 bayes_pls_golite062009
transmembrane transporter activity 2.39695871109024 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
ATPase activity, coupled 2.18396165590908 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 1.93945622138684 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 1.89410061122763 bayes_pls_golite062009
metal ion transmembrane transporter activity 1.63387464349089 bayes_pls_golite062009
hydrolase activity 1.57549510726226 bayes_pls_golite062009
substrate-specific transporter activity 1.29730375126024 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 1.28706187447607 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 1.14579511548336 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
transition metal ion transmembrane transporter activity 0.699203719711999 bayes_pls_golite062009
nucleic acid binding 0.646641337908559 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions 0.600852003734846 bayes_pls_golite062009
active transmembrane transporter activity 0.434775387083003 bayes_pls_golite062009
ATP binding 0.41092997612902 bayes_pls_golite062009
adenyl ribonucleotide binding 0.385813421701492 bayes_pls_golite062009
adenyl nucleotide binding 0.377870145186619 bayes_pls_golite062009
DNA binding 0.334939970943935 bayes_pls_golite062009
primary active transmembrane transporter activity 0.294474570607914 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.282352478532746 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.220608508617331 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.219533217661421 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.219157471322311 bayes_pls_golite062009
cation channel activity 0.192467810264152 bayes_pls_golite062009
iron ion transmembrane transporter activity 0.160869143323446 bayes_pls_golite062009
transcription regulator activity 0.147805393867298 bayes_pls_golite062009
protein binding 0.071010918255742 bayes_pls_golite062009
motor activity 0.0492636236578701 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle