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View Structure Prediction Details

Protein: JEN1
Organism: Saccharomyces cerevisiae
Length: 616 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for JEN1.

Description E-value Query
Range
Subject
Range
JEN1 - Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is dere...
JEN1_YEAST - Carboxylic acid transporter protein homolog OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)...
0.0 [1..616] [1..616]
KHT2_KLULC - Hexose transporter 2 OS=Kluyveromyces lactis GN=KHT2 PE=3 SV=1
0.0 [97..610] [19..563]
gi|16080636, gi|... - gi|2636109|emb|CAB15600.1| ywtG [Bacillus subtilis subsp. subtilis str. 168], gi|16080636|ref|NP_391...
gi|7446721, gi|1... - pir||E70070 metabolite transport protein homolog ywtG - Bacillus subtilis, gi|1894771|emb|CAB07473.1...
0.0 [139..574] [7..443]

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Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSITDEKI SGEQQQPAGR KLYYNTSTFA EPPLVDGEGN PINYEPEVYN PDHEKLYHNP  60
   61 SLPAQSIQDT RDDELLERVY SQDQGV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [87-317]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EYEEDEEDKP NLSAASIKSY ALTRFTSLLH IHEFSWENVN PIPELRKMTW QNWNYFFMGY  60
   61 FAWLSAAWAF FCVSVSVAPL AELYDRPTKD ITWGLGLVLF VRSAGAVIFG LWTDKSSRKW 120
  121 PYITCLFLFV IAQLCTPWCD TYEKFLGVRW ITGIAMGGIY GCASATAIED APVKARSFLS 180
  181 GLFFSAYAMG FIFAIIFYRA FGYFRDDGWK ILFWFSIFLP ILLIFWRLLW P

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [361-559]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VQKYWLLFAY LVVLLVGPNY LTHASQDLLP TMLRAQLGLS KDAVTVIVVV TNIGAICGGM  60
   61 IFGQFMEVTG RRLGLLIACT MGGCFTYPAF MLRSEKAILG AGFMLYFCVF GVWGILPIHL 120
  121 AELAPADARA LVAGLSYQLG NLASAAASTI ETQLADRYPL ERDASGAVIK EDYAKVMAIL 180
  181 TGSVFIFTFA CVFVGHEKF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 95.0
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

Predicted functions:

Term Confidence Notes
transporter activity 4.09176719149278 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transporter activity 3.3426261924492 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.29689809004391 bayes_pls_golite062009
organic acid transmembrane transporter activity 2.15783210522667 bayes_pls_golite062009
ion transmembrane transporter activity 1.94035843948137 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
cation transmembrane transporter activity 1.5181741634556 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
binding 1.01584233411372 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
cation:sugar symporter activity 0.143419068761182 bayes_pls_golite062009
sugar:hydrogen symporter activity 0.143419068761182 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [318-360]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETKYFTKVLK ARKLILSDAV KANGGEPLPK ANFKQKMVSM KRT

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [560-616]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HRDLSSPVMK KYINQVEEYE ADGLSISDIV EQKTECASVK MIDSNVSKTY EEHIETV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 95.0
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle