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View Structure Prediction Details

Protein: DCW1
Organism: Saccharomyces cerevisiae
Length: 449 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DCW1.

Description E-value Query
Range		 Subject
Range
gi|85114207 - gi|85114207|ref|XP_964654.1| hypothetical protein ( (AL442164) conserved hypothetical protein [Neuro...
gi|16945405, gi|... - gi|32417488|ref|XP_329222.1| hypothetical protein ( (AL442164) conserved hypothetical protein [Neuro...
 0.0 [9..445] [16..463]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [23..415] [24..424]
gi|16802811 - gi|16802811|ref|NP_464296.1| hypothetical protein lmo0769 [Listeria monocytogenes EGD-e]
gi|224501927 - gi|224501927|ref|ZP_03670234.1| hypothetical protein LmonFR_05342 [Listeria monocytogenes FSL R2-561...
gi|16410158, gi|... - pir||AI1170 alpha-1,6-mannanase homolog lmo0769 [imported] - Listeria monocytogenes (strain EGD-e), ...
 1.0E-79 [36..361] [7..315]
gi|16799837 - gi|16799837|ref|NP_470105.1| hypothetical protein lin0763 [Listeria innocua Clip11262]
gi|25514586, gi|... - pir||AC1528 alpha-1,6-mannanase homolog lin0763 [imported] - Listeria innocua (strain Clip11262), gi...
 2.0E-79 [36..361] [7..315]
gi|4519505 - gi|4519505|dbj|BAA75632.1| alpha-1,6-mannanase [Bacillus circulans]
 3.0E-77 [66..397] [73..388]
gi|19553963 - gi|19553963|ref|NP_601965.1| hypothetical protein NCgl2674 [Corynebacterium glutamicum ATCC 13032]
 4.0E-63 [58..351] [11..296]
gi|388212 - gi|388212|emb|CAA35191.1| unnamed protein product [Corynebacterium glutamicum]
 3.0E-52 [120..351] [1..229]

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Predicted Domain #1
Region A:
Residues: [1-258] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLVNKVIGLL GVLFATRFTN AVELDLDNYE SLQNATSLIA YGLMDYYTGN QYGKTVGMFS  60
   61 DPYYWWEAGG AWGCMLDYWF FMDNDTYNDE IIAAMIHQAG DDNDYIPLNQ STTEGNDDQA 120
  121 FWGIAAMTAA ERNFTNPPEN EPQWLYLAQA VFNTMALRWD ADSCGGGLRW QIFVWNSGYD 180
  181 YKNTVSNGAL FHIAARLARY TGNQTYVDWA EKVYEWMVGV NLISNGTYKY VYDGVSIDDN 240
  241 CTKVTSYQWT YNQGLLLA

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.89
Match: 1fo2A
Description: Class I alpha-1;2-mannosidase, catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
trehalase activity 4.23942428290504 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 3.78681366425382 bayes_pls_golite062009
alpha,alpha-trehalase activity 3.55712700159445 bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds 3.06084463737498 bayes_pls_golite062009
hydrolase activity 2.4324152075641 bayes_pls_golite062009
glucosidase activity 1.29725707798041 bayes_pls_golite062009
binding 1.09492132758288 bayes_pls_golite062009
catalytic activity 1.0882760267763 bayes_pls_golite062009
glucan 1,4-alpha-glucosidase activity 0.459801253504163 bayes_pls_golite062009
protein binding 0.208998323911823 bayes_pls_golite062009
intramolecular oxidoreductase activity 0.0402220178011703 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [259-449] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSAYLYNFTG SDLWHTRTKE FLNASQVFFH DGIVYEAACQ GPNSCNTDQR SFKAYFARFL  60
   61 GVTAQLVPET RNQIMSWLNT SAIAAAKSCS GGTDGHTCGL NWFNGTWDGM YGLGEQMSAL 120
  121 EVMVNTRALD KPAPYTAENG GSSVGDGAAG TQAQPTNLAP LNITKGSKAG AGIITAVIGI 180
  181 SIVACALWLV F

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.89
Match: 1fo2A
Description: Class I alpha-1;2-mannosidase, catalytic domain
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle