YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: RFA3
Organism: Saccharomyces cerevisiae
Length: 122 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RFA3.

Description E-value Query
Range
Subject
Range
RFA3 - Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded D...
RFA3_YEAST - Replication factor A protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RFA3 PE=1...
8.0E-69 [1..122] [1..122]

Back

Predicted Domain #1
Region A:
Residues: [1-122]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASETPRVDP TEISNVNAPV FRIIAQIKSQ PTESQLILQS PTISSKNGSE VEMITLNNIR  60
   61 VSMNKTFEID SWYEFVCRNN DDGELGFLIL DAVLCKFKEN EDLSLNGVVA LQRLCKKYPE 120
  121 IY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.491 c.47.1 Thioredoxin-like
View Download 0.386 b.60.1 Lipocalins
View Download 0.348 c.23.1 CheY-like
View Download 0.512 c.59.1 MurD-like peptide ligases, peptide-binding domain
View Download 0.372 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.330 c.52.1 Restriction endonuclease-like
View Download 0.328 c.84.1 Phosphoglucomutase, first 3 domains
View Download 0.327 d.58.7 RNA-binding domain, RBD
View Download 0.321 a.79.1 Antitermination factor NusB
View Download 0.315 c.36.1 Thiamin diphosphate-binding fold (THDP-binding)
View Download 0.312 c.52.1 Restriction endonuclease-like
View Download 0.311 c.55.1 Actin-like ATPase domain
View Download 0.290 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.261 d.112.1 Phoshotransferase/anion transport protein
View Download 0.261 b.71.1 Glycosyl hydrolase domain
View Download 0.249 c.57.1 Molybdenum cofactor biosynthesis proteins
View Download 0.247 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.229 d.58.39 Glutamyl tRNA-reductase catalytic, N-terminal domain
View Download 0.219 c.53.1 Resolvase-like
View Download 0.205 c.48.1 TK C-terminal domain-like

Predicted functions:

Term Confidence Notes
telomeric DNA binding 6.80354805962079 bayes_pls_golite062009
single-stranded telomeric DNA binding 5.68297908219419 bayes_pls_golite062009
telomerase inhibitor activity 5.1433503909639 bayes_pls_golite062009
structure-specific DNA binding 3.21942642139833 bayes_pls_golite062009
single-stranded DNA binding 3.2177041772475 bayes_pls_golite062009
nucleic acid binding 3.06958664528424 bayes_pls_golite062009
binding 2.55343783977289 bayes_pls_golite062009
DNA binding 2.39520356118846 bayes_pls_golite062009
structural constituent of ribosome 2.05553707774342 bayes_pls_golite062009
structural molecule activity 1.91392288234828 bayes_pls_golite062009
DNA helicase activity 1.03434608237928 bayes_pls_golite062009
transcription regulator activity 0.786603442061911 bayes_pls_golite062009
DNA-dependent ATPase activity 0.633347054314125 bayes_pls_golite062009
translation regulator activity 0.370723767971907 bayes_pls_golite062009
nuclease activity 0.344602655860014 bayes_pls_golite062009
ribonuclease activity 0.327087435405429 bayes_pls_golite062009
double-stranded DNA binding 0.326586310136168 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.322367891458082 bayes_pls_golite062009
nucleotidyltransferase activity 0.285831998808043 bayes_pls_golite062009
DEAD/H-box RNA helicase binding 0.234313553803999 bayes_pls_golite062009
four-way junction helicase activity 0.149878585899218 bayes_pls_golite062009
exonuclease activity 0.123437412322173 bayes_pls_golite062009
sequence-specific DNA binding 0.112654475341878 bayes_pls_golite062009
protein binding 0.0856707433885143 bayes_pls_golite062009
transcription factor activity 0.0739391344707232 bayes_pls_golite062009
translation initiation factor activity 0.0214826254708589 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle