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View Structure Prediction Details

Protein: MRS1
Organism: Saccharomyces cerevisiae
Length: 363 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MRS1.

Description E-value Query
Range
Subject
Range
gi|3988 - gi|3988|emb|CAA29053.1| unnamed protein product [Saccharomyces cerevisiae]
gi|151943180 - gi|151943180|gb|EDN61515.1| protein required for the splicing of two mitochondrial group I introns (...
0.0 [1..363] [1..363]
MRS1_SACPA - Mitochondrial RNA-splicing protein MRS1 OS=Saccharomyces paradoxus GN=MRS1 PE=4 SV=1
MRS1_SACDO - Mitochondrial RNA-splicing protein MRS1 OS=Saccharomyces douglasii GN=MRS1 PE=4 SV=1
0.0 [1..363] [1..363]
cce1 - mitochondrial cruciform cutting endonuclease Cce1
CCE1_SCHPO - Cruciform cutting endonuclease 1, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 2484...
0.004 [73..218] [42..190]

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Predicted Domain #1
Region A:
Residues: [1-69]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPKNITRSV IPAIDLYCRK ANFKTLKSLS MILGSKKEWY DTKKAPLRTF LVSRCGIFEQ  60
   61 LRGRLVEDG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
nuclease activity 2.26556994009539 bayes_pls_golite062009
2.00836055708423 bayes_pls_golite062009
ribonuclease activity 1.78000986678433 bayes_pls_golite062009
exoribonuclease activity 1.32264233824256 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 1.27522285482764 bayes_pls_golite062009
catalytic activity 1.25233849524628 bayes_pls_golite062009
transcription regulator activity 1.20586272399219 bayes_pls_golite062009
nucleic acid binding 1.15524113948715 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.05288004668073 bayes_pls_golite062009
3'-5'-exoribonuclease activity 0.99953538134208 bayes_pls_golite062009
exonuclease activity 0.967966366451269 bayes_pls_golite062009
DNA binding 0.943022297191079 bayes_pls_golite062009
binding 0.925646122805083 bayes_pls_golite062009
endoribonuclease activity, producing 5'-phosphomonoesters 0.830848153280868 bayes_pls_golite062009
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.681014317532767 bayes_pls_golite062009
endonuclease activity 0.635517699603511 bayes_pls_golite062009
3'-5' exonuclease activity 0.4571735090405 bayes_pls_golite062009
transcription factor activity 0.350780284864953 bayes_pls_golite062009
RNA binding 0.239100354404122 bayes_pls_golite062009
protein binding 0.035326007863533 bayes_pls_golite062009
endoribonuclease activity 0.016619833072142 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [70-218]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVNLFSVFLT NDSFSFCKMT VDDKFNTSLV DWQKIPFDST FATDRRQNIS LLPVDTLFAT  60
   61 EKIISILGVS PNMTNLVSIE RERSDLVDFN CKLQSNILEH LLYAKCQGVY VTSTNEKARL 120
  121 LAAVCNPEFI DTFWCELTPI RVSLKENPS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 1kcfA_
Description: Mitochondrial resolvase ydc2 N-terminal domain; Mitochondrial resolvase ydc2 catalytic domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [219-363]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISVPREYQMY DPVVRATIKE VVTKRLLRSA FDNDIDPLMC LHLDKGWKLK FPILSSTTGL  60
   61 NFSLKDCLSL DTGKDASDMT EVFLATMESS KVLRTYSNLV DIVMKDNGRL DSGVLKQFND 120
  121 YVKQEKLNLQ HFQAGSSKFL KGAKI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle