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View Structure Prediction Details

Protein: YIL166C
Organism: Saccharomyces cerevisiae
Length: 542 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YIL166C.

Description E-value Query
Range		 Subject
Range
STP10_ARATH - Sugar transport protein 10 OS=Arabidopsis thaliana GN=STP10 PE=2 SV=1
 3.0E-89 [74..528] [21..497]
gi|115470211, gi... - gi|50508995|dbj|BAD31944.1| putative monosaccharide transport protein MST1 [Oryza sativa Japonica Gr...
gi|125556956 - gi|125556956|gb|EAZ02492.1| hypothetical protein OsI_24597 [Oryza sativa Indica Group]
gi|11991114 - gi|11991114|dbj|BAB19864.1| monosaccharide transporter 3 [Oryza sativa]
 6.0E-89 [73..516] [18..485]
SNF3 - Plasma membrane low glucose sensor that regulates glucose transport; contains 12 predicted transmemb...
SNF3_YEAST - High-affinity glucose transporter SNF3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=S...
 9.0E-89 [11..540] [37..581]
STC_RICCO - Sugar carrier protein C OS=Ricinus communis GN=STC PE=2 SV=1
 9.0E-89 [61..523] [8..494]
KHT2_KLULC - Hexose transporter 2 OS=Kluyveromyces lactis GN=KHT2 PE=3 SV=1
 2.0E-88 [54..529] [35..536]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 3.0E-88 [74..524] [19..493]

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Predicted Domain #1
Region A:
Residues: [1-62] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVQKEEYDI VEKAQLSVSA ESLTSDSESI SHNPFDDFHK AERWRKVYES SGYEGLSKFD  60
   61 PE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
substrate-specific transmembrane transporter activity 5.46247398538901 bayes_pls_golite062009
ion transmembrane transporter activity 4.58978526526921 bayes_pls_golite062009
transporter activity 4.09176719149278 bayes_pls_golite062009
anion transmembrane transporter activity 3.94605227012838 bayes_pls_golite062009
cation transmembrane transporter activity 3.88180006470231 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 2.52916479889426 bayes_pls_golite062009
organic acid transmembrane transporter activity 2.15783210522667 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
binding 0.873217664940684 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
phosphate transmembrane transporter activity 0.312628600969375 bayes_pls_golite062009
cation:sugar symporter activity 0.143419068761182 bayes_pls_golite062009
sugar:hydrogen symporter activity 0.143419068761182 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [63-263] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FTWTKDEEKK LVRKMDLKIF LWVFIMFAFL DLIRKNIARA VSDNFIVDLK MNTNDYNLGQ  60
   61 TVYLVIFLAS ELPGNLLSKR FGPERVIPVQ IVLWSVICIT QAGLKNRGQF IATRCLLGMV 120
  121 QGGFIPDNIL YLSYYYTGAE LTFRLSFFWC AIPLFQILGS LLASGIIEMR GIHNLAGWQY 180
  181 LFIIEGFLSL SVGVASFYLM R

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [306-509] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RQPVTFKEIL YTLTEFDLWP LFIQGITAFI SLQTVGSYLS LILKSLNYST FLSNILAIPG  60
   61 QALLLINLPL AALLSRKLKE KSLCVGIANV WVLPFIVSLV ALPTDTNPWI KYILLTGILG 120
  121 LPYTHSILAG WVSEISNSVR SRTVGTALYN MSAQVGAIIA SNMYRNDDKP YYTRGNKILL 180
  181 GFTCFNICMA VATKFYYISR NKYK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.045757
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

Predicted Domain #3
Region A:
Residues: [264-305] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RGPTQTGESA FHKGKSLFTE YEEKIMVNRI LRDDPSKGDM SN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [510-542] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRKWNSMTKE EQINYLDTTK DKGMKRLDYR FIH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.045757
Match: 1ja5A_
Description: No description for 1ja5A_ was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle