| Protein: | INP51 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 946 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for INP51.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..946] | [1..946] |
|
|
0.0 | [1..944] | [1..957] |
|
|
0.0 | [22..875] | [9..914] |
|
|
0.0 | [22..875] | [9..914] |
|
|
0.0 | [22..875] | [9..914] |
|
|
0.0 | [22..875] | [9..914] |
|
|
0.0 | [22..875] | [9..914] |
|
|
0.0 | [43..879] | [35..921] |
|
Region A: Residues: [1-408] |
1 11 21 31 41 51
| | | | | |
1 MRLFIGRRSR SIVISSNNYC LSFQRLRSIP GASSQQRQLS KTPSVTIKSY PDTDLSSDSN 60
61 YLEVKSCIFN GLLGLVCLNG DIYVAVISGV QNVGFPRWKL IDHQVRPSES IYKVLDVDFY 120
121 SLENDVFDYL LCERSEQNYD KLIHEHPCGP LKKLFSDGTF YYSRDFDISN IVKNHGLSHN 180
181 LEYTVDNQDL SFIWNANLAS EVINWRSKIS NEEKQLFANA GFLTFVIRGY CKTALIEDGP 240
241 NTASITIISR ISTESKQDTL ELEGISEDGR VSLFVETEIV VTTEKFIFSY TQVNGSIPLF 300
301 WESVESQLLY GKKIKVTKDS IEAQGAFDRH FDNLTSKYGV VSIVNIIKPK SESQEKLALT 360
361 YKDCAESKGI KITNIEYSSS VLTKSPHKLL YLLKQDIYEF GAFAYDIS
|
| Detection Method: |  |
| Confidence: | 149.107905 |
| Match: | PF02383 |
| Description: | SacI homology domain |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [409-496] |
1 11 21 31 41 51
| | | | | |
1 RGIYFAKQTG VLRISAFDSI EKPNTVERLV SKEVLELTTN EIDVFELTSP FLDAHDKLWS 60
61 ENYYWLDRTY TKHTKNSGKY TKVYSKLF
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.544 | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.658 | a.74.1 | Cyclin-like |
| View | Download | 0.638 | c.55.4 | Translational machinery components |
| View | Download | 0.528 | a.165.1 | Myosin phosphatase inhibitor 17kDa protein, CPI-17 |
| View | Download | 0.512 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.506 | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.481 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.474 | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.455 | a.74.1 | Cyclin-like |
| View | Download | 0.445 | a.29.2 | Bromodomain |
| View | Download | 0.432 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.428 | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.416 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.406 | a.179.1 | Replisome organizer (g39p helicase loader/inhibitor protein) |
| View | Download | 0.402 | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.400 | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.398 | a.74.1 | Cyclin-like |
| View | Download | 0.395 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.386 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.384 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.376 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.366 | a.71.1 | Endoplasmic reticulum protein ERP29, C-domain |
| View | Download | 0.363 | d.26.1 | FKBP-like |
| View | Download | 0.347 | a.74.1 | Cyclin-like |
| View | Download | 0.327 | a.36.1 | Signal peptide-binding domain |
| View | Download | 0.323 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.318 | a.1.1 | Globin-like |
| View | Download | 0.311 | a.74.1 | Cyclin-like |
| View | Download | 0.292 | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.290 | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.290 | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.289 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.285 | a.85.1 | Hemocyanin, N-terminal domain |
| View | Download | 0.273 | a.118.1 | ARM repeat |
| View | Download | 0.269 | a.26.1 | 4-helical cytokines |
| View | Download | 0.266 | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.264 | d.58.20 | NAD-binding domain of HMG-CoA reductase |
| View | Download | 0.258 | d.203.1 | DsrC, the gamma subunit of dissimilatory sulfite reductase |
| View | Download | 0.256 | a.74.1 | Cyclin-like |
| View | Download | 0.251 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.244 | a.4.1 | Homeodomain-like |
| View | Download | 0.243 | a.118.8 | TPR-like |
| View | Download | 0.241 | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.237 | c.55.7 | Methylated DNA-protein cysteine methyltransferase domain |
| View | Download | 0.231 | a.69.3 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain |
| View | Download | 0.231 | a.60.1 | SAM/Pointed domain |
| View | Download | 0.230 | a.46.1 | Methionine synthase domain |
| View | Download | 0.223 | c.59.1 | MurD-like peptide ligases, peptide-binding domain |
| View | Download | 0.222 | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.207 | a.39.1 | EF-hand |
| View | Download | 0.206 | c.55.3 | Ribonuclease H-like |
| View | Download | 0.204 | a.21.1 | HMG-box |
| View | Download | 0.201 | a.4.5 | "Winged helix" DNA-binding domain |
|
Region A: Residues: [497-879] |
1 11 21 31 41 51
| | | | | |
1 GSRVRLYDPL HIYISQYLKQ LRSKYTFEKD ISIFAGTFNI SGKIPKDDIK DWIFPKSMSK 60
61 EDEMADLYVI GLEEVVELTP GHMLATDPYV RQFWEKKILT LLNGPGRKKK YIRLWSTQLG 120
121 GILLLLFMNE TEYSKVKHIE GDVKKTGFGG MASNKGAVAV SFKYSATRFC VLVSHLAAGL 180
181 ENVEQRHNDY KTIAKSIRFS KGLRIKDHDA IIWMGDFNYR ILMSNEDVRR KIVSKEYASL 240
241 FEKDQLNQQM IAGESFPYFH EMAIDFPPTY KFDPGTKNYD TSEKMRIPAW TDRILSRGEV 300
301 LEQLEYKCCE DILFSDHRPV YAIFRARVTV VDEQKKTTLG TQIYEKIMER LEGLDDDEKI 360
361 AVLSDDAFVI ESFEGSDSIA GPT
|
| Detection Method: | |
| Confidence: | 962.9897 |
| Match: | 1i9yA_ |
| Description: | Synaptojanin, IPP5C domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [880-946] |
1 11 21 31 41 51
| | | | | |
1 HSPTPIPEPK RGRKLPPPSS DLKKWWIGSG KQVKVVLDVD PAVYMINPKR DPNPFVENED 60
61 EPLFIER
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.482 | d.9.1 | Interleukin 8-like chemokines |
| View | Download | 0.462 | d.50.1 | dsRNA-binding domain-like |
| View | Download | 0.600 | d.9.2 | Description not found. |
| View | Download | 0.483 | d.9.2 | Description not found. |
| View | Download | 0.441 | b.24.1 | Hyaluronate lyase-like, C-terminal domain |
| View | Download | 0.437 | g.28.1 | Thyroglobulin type-1 domain |
| View | Download | 0.429 | d.50.1 | dsRNA-binding domain-like |
| View | Download | 0.411 | d.74.2 | C-terminal domain of arginine repressor |
| View | Download | 0.410 | d.9.1 | Interleukin 8-like chemokines |
| View | Download | 0.399 | b.1.18 | E set domains |
| View | Download | 0.397 | b.49.1 | N-terminal domain of alpha and beta subunits of F1 ATP synthase |
| View | Download | 0.396 | d.9.1 | Interleukin 8-like chemokines |
| View | Download | 0.386 | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.376 | d.9.1 | Interleukin 8-like chemokines |
| View | Download | 0.359 | d.58.17 | Metal-binding domain |
| View | Download | 0.335 | g.3.7 | Scorpion toxin-like |
| View | Download | 0.324 | d.49.1 | Signal recognition particle alu RNA binding heterodimer, SRP9/14 |
| View | Download | 0.321 | d.9.2 | Description not found. |
| View | Download | 0.310 | b.71.1 | Glycosyl hydrolase domain |
| View | Download | 0.271 | b.114.1 | N-utilization substance G protein NusG, insert domain |
| View | Download | 0.256 | b.7.2 | Periplasmic chaperone C-domain |
| View | Download | 0.221 | b.71.1 | Glycosyl hydrolase domain |
| View | Download | 0.214 | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.213 | d.19.1 | MHC antigen-recognition domain |
| Term | Confidence | Notes |
| hydrolase activity, acting on ester bonds | 6.16986356176974 | bayes_pls_golite062009 |
| phosphatase activity | 5.90350467872925 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 5.84927924311254 | bayes_pls_golite062009 |
| phosphatidylinositol bisphosphate phosphatase activity | 5.76202422677892 | bayes_pls_golite062009 |
| phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity | 5.57319461575586 | bayes_pls_golite062009 |
| phosphoinositide 5-phosphatase activity | 5.57319461575586 | bayes_pls_golite062009 |
| inositol-polyphosphate 5-phosphatase activity | 4.20215185632047 | bayes_pls_golite062009 |
| inositol or phosphatidylinositol phosphatase activity | 3.88924621938812 | bayes_pls_golite062009 |
| lipid phosphatase activity | 3.07322777760243 | bayes_pls_golite062009 |
| phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity | 2.64934277728302 | bayes_pls_golite062009 |
| phosphatidylinositol-4-phosphate phosphatase activity | 2.64934277728302 | bayes_pls_golite062009 |
| inositol trisphosphate phosphatase activity | 2.32855198081691 | bayes_pls_golite062009 |
| hydrolase activity | 2.1345957248514 | bayes_pls_golite062009 |
| phosphatidylinositol-3-phosphatase activity | 1.98439062808392 | bayes_pls_golite062009 |
| catalytic activity | 1.76511376991978 | bayes_pls_golite062009 |
| DNA binding | 1.45924870577723 | bayes_pls_golite062009 |
| phosphatidylinositol trisphosphate phosphatase activity | 1.43486520454637 | bayes_pls_golite062009 |
| nucleic acid binding | 1.38966944580562 | bayes_pls_golite062009 |
| transcription regulator activity | 1.37597495586534 | bayes_pls_golite062009 |
| binding | 1.31660174492743 | bayes_pls_golite062009 |
| phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity | 0.938520838175434 | bayes_pls_golite062009 |
| nuclease activity | 0.782488606133604 | bayes_pls_golite062009 |
| deoxyribonuclease activity | 0.620825895803427 | bayes_pls_golite062009 |
| protein binding | 0.476649214025345 | bayes_pls_golite062009 |
| transcription activator activity | 0.239217168608234 | bayes_pls_golite062009 |
| exonuclease activity | 0.219613338022829 | bayes_pls_golite062009 |
| exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 0.213742479001316 | bayes_pls_golite062009 |
| transcription factor binding | 0.19603200433138 | bayes_pls_golite062009 |
| phosphoric diester hydrolase activity | 0.137101173922861 | bayes_pls_golite062009 |
|
Region A: Residues: [844-946] |
1 11 21 31 41 51
| | | | | |
1 MERLEGLDDD EKIAVLSDDA FVIESFEGSD SIAGPTHSPT PIPEPKRGRK LPPPSSDLKK 60
61 WWIGSGKQVK VVLDVDPAVY MINPKRDPNP FVENEDEPLF IER
|
| Detection Method: | |
| Confidence: | 18.522879 |
| Match: | 2qv2A |
| Description: | No description for 2qv2A was found. |
