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View Structure Prediction Details

Protein: NAS6
Organism: Saccharomyces cerevisiae
Length: 228 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NAS6.

Description E-value Query
Range		 Subject
Range
ANK2 - ankyrin 2, neuronal
 2.0E-63 [2..227] [299..519]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 2.0E-62 [2..227] [433..653]
gi|3885972 - gi|3885972|gb|AAC78143.1| 270 kDa ankyrin G isoform [Rattus norvegicus]
 1.0E-59 [2..227] [441..661]
gi|18204817 - gi|18204817|gb|AAH21490.1| Dapk1 protein [Mus musculus]
 2.0E-58 [2..228] [331..548]

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Predicted Domain #1
Region A:
Residues: [1-60] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNYPLHQAC MENEFFKVQE LLHSKPSLLL QKDQDGRIPL HWSVSFQAHE ITSFLLSKME  60
   61

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 111.68867
Match: 1iknD_
Description: I-kappa-B-alpha
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 2.43232200709693 bayes_pls_golite062009
binding 2.41068257517762 bayes_pls_golite062009
cytoskeletal protein binding 1.93050618316228 bayes_pls_golite062009
protein binding 1.54890102798695 bayes_pls_golite062009
structural constituent of cytoskeleton 1.29094941611102 bayes_pls_golite062009
ubiquitin-protein ligase activity 1.23556500721571 bayes_pls_golite062009
small conjugating protein ligase activity 1.13900029077952 bayes_pls_golite062009
structural molecule activity 0.808967137205604 bayes_pls_golite062009
enzyme binding 0.60140077251711 bayes_pls_golite062009
transcription regulator activity 0.327689573161126 bayes_pls_golite062009
nucleic acid binding 0.280340492381105 bayes_pls_golite062009
acid-amino acid ligase activity 0.247967126091535 bayes_pls_golite062009
actin binding 0.168912685840912 bayes_pls_golite062009
cyclin-dependent protein kinase regulator activity 0.0462605323512499 bayes_pls_golite062009
DNA binding 0.0016834194928852 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [61-134] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVNLDDYPDD SGWTPFHIAC SVGNLEVVKS LYDRPLKPDL NKITNQGVTC LHLAVGKKWF  60
   61 EVSQFLIENG ASVR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 111.68867
Match: 1iknD_
Description: I-kappa-B-alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [135-228] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKDKFNQIPL HRAASVGSLK LIELLCGLGK SAVNWQDKQG WTPLFHALAE GHGDAAVLLV  60
   61 EKYGAEYDLV DNKGAKAEDV ALNEQVKKFF LNNV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 111.68867
Match: 1iknD_
Description: I-kappa-B-alpha
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle