YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: KAP122
Organism: Saccharomyces cerevisiae
Length: 1081 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KAP122.

Description E-value Query
Range
Subject
Range
KAP122 - Karyopherin beta, responsible for import of the Toa1p-Toa2p complex into the nucleus; binds to nucle...
KA122_YEAST - Importin beta-like protein KAP122 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KAP122...
0.0 [1..1081] [1..1081]
kap111 - karyopherin Kap111
KA111_SCHPO - Importin beta-like protein kap111 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=kap111 P...
0.0 [10..1076] [12..978]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [278..1076] [134..884]
gi|14198268, gi|... - gi|41281425|ref|NP_055467.2| importin 13 [Homo sapiens], gi|14198268|gb|AAH08194.1| Importin 13 [Hom...
0.0 [275..1076] [201..954]
IPO13_RAT - Importin-13 OS=Rattus norvegicus GN=Ipo13 PE=2 SV=1
0.0 [275..1076] [201..954]
gi|3006178 - gi|3006178|emb|CAA18398.1| SPBC11G11.07 [Schizosaccharomyces pombe]
0.0 [438..1074] [1..604]

Back

Predicted Domain #1
Region A:
Residues: [1-393]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSIHEVVAL IEELYSPHPK HDVNQIQQSL QSIQKSEQGF HLANELLSDD KYSANVKYFG  60
   61 ALTLTVQLNT RGENDYETLW NVFRSNLLYL TKFSTLYVSN PNMYGQSLII IKKLMSNLSL 120
  121 IFTKINDPQL NNAGNENMIK QWNNPINTFI QLMSVQNQNI NADQLLLDSI NCSLTYEQLS 180
  181 QFVSLSQKHN ELALTFTEVI VEDLTKFQTK RHSMSQIHEV VHEHLYISTM ALINLNLTAQ 240
  241 AVFNPTVFDC ITAWINYISL TRSVSSSGRM DLSEIFQNLI DLMYQSTEGS DGYENAEKIL 300
  301 TIFGNVFAND PLLMSYDLRQ QIECIFLGVV RPDSGITDIS NKNSWMLQYM NYLVTNDFFS 360
  361 ELKELAICIV DFLQINTLSV CNKLFTNIQA ADN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
protein transporter activity 4.20717321392127 bayes_pls_golite062009
binding 2.76236644111948 bayes_pls_golite062009
protein transmembrane transporter activity 2.41503596785122 bayes_pls_golite062009
transporter activity 2.3766833486706 bayes_pls_golite062009
substrate-specific transporter activity 2.12926593993985 bayes_pls_golite062009
protein binding 1.5114863464349 bayes_pls_golite062009
nuclear localization sequence binding 1.4950300017044 bayes_pls_golite062009
transmembrane transporter activity 1.2724388835449 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.04982314606251 bayes_pls_golite062009
nuclear export signal receptor activity 0.86012890098627 bayes_pls_golite062009
RNA binding 0.821282292359571 bayes_pls_golite062009
nucleic acid binding 0.753616504399234 bayes_pls_golite062009
molecular transducer activity 0.462279025397785 bayes_pls_golite062009
signal transducer activity 0.462279025397785 bayes_pls_golite062009
signal sequence binding 0.279693431859311 bayes_pls_golite062009
active transmembrane transporter activity 0.260663498540354 bayes_pls_golite062009
ion transmembrane transporter activity 0.256036243669218 bayes_pls_golite062009
primary active transmembrane transporter activity 0.234271600707329 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.225395946682209 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.186601655036333 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.183072614802483 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.182751938544977 bayes_pls_golite062009
transcription regulator activity 0.147335771550418 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.109435859778099 bayes_pls_golite062009
DNA binding 0.0985062788532622 bayes_pls_golite062009
pyrophosphatase activity 0.0728493557966827 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0641324729536009 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0615190129942244 bayes_pls_golite062009
cation transmembrane transporter activity 0.0475280280823402 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [394-1081]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GQVQDEYIQE YIKVLLQMTN FPLTPVLQEF FSVRMVDFWL DLSDAYTNLA SETLRPNSIE  60
   61 LSTQIFQQLI NIYLPKISLS VKQRIIEEEG ESTSVNEFED FRNAVSDLAQ SLWSILGNDN 120
  121 LTNVLIDGMG QMPAASDETL IIKDTDVLFR IETMCFVLNT ILVDMTLSES PWIKNIVDAN 180
  181 KFFNQNVISV FQTGFQTSAS TKVSQILKLD FVRTSTTLIG TLAGYFKQEP FQLNPYVEAL 240
  241 FQGLHTCTNF TSKNEQEKIS NDKLEVMVIK TVSTLCETCR EELTPYLMHF ISFLNTVIMP 300
  301 DSNVSHFTRT KLVRSIGYVV QCQVSNGPEE QAKYILQLTN LLSGSIEHCL ASSVQLQEQQ 360
  361 DYINCLLYCI SELATSLIQP TEIIENDALL QRLSEFQSFW SSDPLQIRSK IMCTIDKVLD 420
  421 NSIYCKNSAF VEIGCLIVGK GLNLPDGEPY FLKYNMSEVM NFVLRHVPNC ELATCLPYFV 480
  481 YLLEKLISEF RKELTPQEFD FMFEKILLVY YDAYIINDPD LLQMTIGFVN NVLDVKPGLA 540
  541 IGSKHWTSFI LPQFLKLIPS REKFTIVAVA KFWTKLINNK KYNQEELTTV RQQVSSIGGD 600
  601 LVYQIMYGLF HTQRSDLNSY TDLLRALVAK FPIEAREWLV AVLPQICNNP AGHEKFINKL 660
  661 LITRGSRAAG NVILQWWLDC TTLPNYQG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [929-1081]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPGLAIGSKH WTSFILPQFL KLIPSREKFT IVAVAKFWTK LINNKKYNQE ELTTVRQQVS  60
   61 SIGGDLVYQI MYGLFHTQRS DLNSYTDLLR ALVAKFPIEA REWLVAVLPQ ICNNPAGHEK 120
  121 FINKLLITRG SRAAGNVILQ WWLDCTTLPN YQG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle