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View Structure Prediction Details

Protein: RPN14
Organism: Saccharomyces cerevisiae
Length: 417 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPN14.

Description E-value Query
Range
Subject
Range
gi|17225208 - gi|17225208|gb|AAL37300.1|AF323584_1 beta transducin-like protein HET-E2C*40 [Podospora anserina]
0.0 [3..413] [842..1247]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [3..415] [907..1314]

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Predicted Domain #1
Region A:
Residues: [1-417]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKTITVAHI QYDFKAVLEE NDENDDEFYI NVDKNLNEIK EHKIVVLGNS RGVDAGKGNT  60
   61 FEKVGSHLYK ARLDGHDFLF NTIIRDGSKM LKRADYTAVD TAKLQMRRFI LGTTEGDIKV 120
  121 LDSNFNLQRE IDQAHVSEIT KLKFFPSGEA LISSSQDMQL KIWSVKDGSN PRTLIGHRAT 180
  181 VTDIAIIDRG RNVLSASLDG TIRLWECGTG TTIHTFNRKE NPHDGVNSIA LFVGTDRQLH 240
  241 EISTSKKNNL EFGTYGKYVI AGHVSGVITV HNVFSKEQTI QLPSKFTCSC NSLTVDGNNA 300
  301 NYIYAGYENG MLAQWDLRSP ECPVGEFLIN EGTPINNVYF AAGALFVSSG FDTSIKLDII 360
  361 SDPESERPAI EFETPTFLVS NDDEVSQFCY VSDDESNGEV LEVGKNNFCA LYNLSNP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 126.68867
Match: 1erjA_
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.2778252170547 bayes_pls_golite062009
protein binding 1.42618832381942 bayes_pls_golite062009
ubiquitin-protein ligase activity 1.27579156500929 bayes_pls_golite062009
small conjugating protein ligase activity 1.25374976623953 bayes_pls_golite062009
nucleic acid binding 0.693814013902061 bayes_pls_golite062009
acid-amino acid ligase activity 0.372795124253564 bayes_pls_golite062009
transcription regulator activity 0.190100099674138 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [358-417]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DIISDPESER PAIEFETPTF LVSNDDEVSQ FCYVSDDESN GEVLEVGKNN FCALYNLSNP  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 65.39794
Match: 1p22A
Description: F-box/WD-repeat protein 1 (beta-TRCP1)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle