| Protein: | VPS3 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1011 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VPS3.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1011] | [1..1011] |
|
|
9.0E-86 | [135..436] | [9..308] |
|
|
2.0E-85 | [135..436] | [9..308] |
|
|
4.0E-72 | [146..444] | [18..325] |
|
|
2.0E-60 | [135..435] | [10..341] |
|
|
2.0E-58 | [143..401] | [15..292] |
|
Region A: Residues: [1-98] |
1 11 21 31 41 51
| | | | | |
1 MVKKKTNNDK GKEVKENEGK LDIDSESSPH ERENDKKKTE DDSLRATESE ETNTHNANPN 60
61 ETVRADKFSQ EESRPIEDSP HTDKNTAQES CQPSSAED
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [99-726] |
1 11 21 31 41 51
| | | | | |
1 NVINTDITSL NEKTSTNDEQ EKGLPLKISE GPFTISTLLD NVPSDLIYTC CEAYENHIFL 60
61 GTTTGDLLHY FELERGNYML VSQTKFDAES NSKIDKILLL PKVEGALILC DNELVLFILP 120
121 EFAPRPNTTR LKGISDVVIC NFSRSSKAYR IYAFHAEGVR LLKISADSLV LTKAFNFKLI 180
181 DKACAHEETL MVSKLNSYEL INLKSSQVIP LFRISETDED LEPIITSFNE QSEFLVCSGG 240
241 GSYDSGAMAL VVNHHGDIIK GTIVLKNYPR NVIVEFPYII AESAFQSVDI YSALPSEKSQ 300
301 LLQSITTSGS DLKISKSDNV FTNTNNSEEF KEKIFNKLRL EPLTHSDNKF RIERERAFVE 360
361 ESYEEKTSLI VYNNLGIHLL VPTPMVLRFT SCEESEIDNI EDQLKKLAKK DLTKFEHIEA 420
421 KYLMSLLLFL MTLHYDHIED EVMKKWCDFS DKVDIRILFY MFGWKVYSEI WCFHGLINIV 480
481 ERLKSLKLTN KCENILKMLL MMKNELKKKN KTGLLTNDFD DIMKTIDITL FKLRLEKKET 540
541 ITVDMFERES YDEIIREINL HDDKLPRIEL LIEIYKEKGE YLKALNLLRE AGDYISLVSF 600
601 IEENLKKLPE DYIKERIADD LLLTLKQG
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [727-1011] |
1 11 21 31 41 51
| | | | | |
1 DENTEECAIK KVLKILDMAC INKNDFLNKI PAEETSLKVS FIEQLGVQNS NDSKFLFNYY 60
61 LAKLREIINQ SNIWSILGDF IKEYKDDFAY DKTDITNFIH IKLKHSLQCE NFSKYYEKCE 120
121 NLKSENEKDD EFINFTFDEI SKIDKEHILT LLFFPNELTN WVSSEELLKI YLSFNDFRSV 180
181 EKYIGKQNLV AVMKQYLDIS SLNYSVELVT NLLQRNFELL DDTDIQLKIL ETIPSVFPVQ 240
241 TISELLLKVL IKYQEKKEES NLRKCLLKNQ ISISDELSRN FDSQG
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [407-491] |
1 11 21 31 41 51
| | | | | |
1 GSDLKISKSD NVFTNTNNSE EFKEKIFNKL RLEPLTHSDN KFRIERERAF VEESYEEKTS 60
61 LIVYNNLGIH LLVPTPMVLR FTSCE
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [492-1011] |
1 11 21 31 41 51
| | | | | |
1 ESEIDNIEDQ LKKLAKKDLT KFEHIEAKYL MSLLLFLMTL HYDHIEDEVM KKWCDFSDKV 60
61 DIRILFYMFG WKVYSEIWCF HGLINIVERL KSLKLTNKCE NILKMLLMMK NELKKKNKTG 120
121 LLTNDFDDIM KTIDITLFKL RLEKKETITV DMFERESYDE IIREINLHDD KLPRIELLIE 180
181 IYKEKGEYLK ALNLLREAGD YISLVSFIEE NLKKLPEDYI KERIADDLLL TLKQGDENTE 240
241 ECAIKKVLKI LDMACINKND FLNKIPAEET SLKVSFIEQL GVQNSNDSKF LFNYYLAKLR 300
301 EIINQSNIWS ILGDFIKEYK DDFAYDKTDI TNFIHIKLKH SLQCENFSKY YEKCENLKSE 360
361 NEKDDEFINF TFDEISKIDK EHILTLLFFP NELTNWVSSE ELLKIYLSFN DFRSVEKYIG 420
421 KQNLVAVMKQ YLDISSLNYS VELVTNLLQR NFELLDDTDI QLKILETIPS VFPVQTISEL 480
481 LLKVLIKYQE KKEESNLRKC LLKNQISISD ELSRNFDSQG
|
| Detection Method: | |
| Confidence: | 0.962 |
| Match: | 1b89A |
| Description: | Clathrin heavy chain proximal leg segment |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein transporter activity | 2.99345877012947 | bayes_pls_golite062009 |
| binding | 2.33303322187387 | bayes_pls_golite062009 |
| transporter activity | 1.85346023606579 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 1.51565516399356 | bayes_pls_golite062009 |
| protein binding | 1.5114863464349 | bayes_pls_golite062009 |
| protein transmembrane transporter activity | 1.12112006227201 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.710528717985301 | bayes_pls_golite062009 |
| proton-transporting ATPase activity, rotational mechanism | 0.68860343348996 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.39311980867126 | bayes_pls_golite062009 |
| signal sequence binding | 0.279693431859311 | bayes_pls_golite062009 |
| nuclear localization sequence binding | 0.241630311762028 | bayes_pls_golite062009 |
| nucleic acid binding | 0.170608604167104 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.109435859778099 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.0728493557966827 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.0641324729536009 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.0615190129942244 | bayes_pls_golite062009 |
