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View Structure Prediction Details

Protein: DIT2
Organism: Saccharomyces cerevisiae
Length: 489 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DIT2.

Description E-value Query
Range
Subject
Range
F3PH_ARATH - Flavonoid 3'-monooxygenase OS=Arabidopsis thaliana GN=CYP75B1 PE=1 SV=1
0.0 [1..486] [1..504]
C93A1_SOYBN - 3,9-dihydroxypterocarpan 6A-monooxygenase OS=Glycine max GN=CYP93A1 PE=1 SV=1
0.0 [9..486] [5..504]
gi|12231886 - gi|12231886|gb|AAG49301.1|AF313491_1 flavonoid 3'-hydroxylase [Matthiola incana]
0.0 [2..487] [1..505]
gi|12231914 - gi|12231914|gb|AAG49315.1|AF315465_1 flavonoid 3'-hydroxylase [Pelargonium x hortorum]
0.0 [1..485] [4..506]
gi|12331298 - gi|12331298|emb|CAC24711.1| cytochrome P450 [Solanum tuberosum]
0.0 [1..483] [1..496]
C71A1_PERAE - Cytochrome P450 71A1 OS=Persea americana GN=CYP71A1 PE=1 SV=2
0.0 [3..481] [1..492]

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Predicted Domain #1
Region A:
Residues: [1-489]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELLKLLCLI LFLTLSYVAF AIIVPPLNFP KNIPTIPFYV VFLPVIFPID QTELYDLYIR  60
   61 ESMEKYGAVK FFFGSRWNIL VSRSEYLAQI FKDEDTFAKS GNQKKIPYSA LAAYTGDNVI 120
  121 SAYGAVWRNY RNAVTNGLQH FDDAPIFKNA KILCTLIKNR LLEGQTSIPM GPLSQRMALD 180
  181 NISQVALGFD FGALTHEKNA FHEHLIRIKK QIFHPFFLTF PFLDVLPIPS RKKAFKDVVS 240
  241 FRELLVKRVQ DELVNNYKFE QTTFAASDLI RAHNNEIIDY KQLTDNIVII LVAGHENPQL 300
  301 LFNSSLYLLA KYSNEWQEKL RKEVNGITDP KGLADLPLLN AFLFEVVRMY PPLSTIINRC 360
  361 TTKTCKLGAE IVIPKGVYVG YNNFGTSHDP KTWGTTADDF KPERWGSDIE TIRKNWRMAK 420
  421 NRCAVTGFHG GRRACLGEKL ALTEMRISLA EMLKQFRWSL DPEWEEKLTP AGPLCPLNLK 480
  481 LKFNENIME

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 171.228787
Match: 2c17A_
Description: No description for 2c17A_ was found.

Predicted functions:

Term Confidence Notes
arachidonic acid monooxygenase activity 6.76823710927794 bayes_pls_golite062009
fatty acid (omega-1)-hydroxylase activity 6.3313834755701 bayes_pls_golite062009
arachidonic acid epoxygenase activity 4.80764258881036 bayes_pls_golite062009
monooxygenase activity 4.39701968168633 bayes_pls_golite062009
steroid hydroxylase activity 3.34643016685712 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3.24344797738248 bayes_pls_golite062009
oxygen binding 2.77495508953933 bayes_pls_golite062009
retinoic acid 4-hydroxylase activity 2.60901411823382 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2.56821164444595 bayes_pls_golite062009
oxidoreductase activity 2.35847923992364 bayes_pls_golite062009
arachidonic acid 11,12-epoxygenase activity 2.0071742914584 bayes_pls_golite062009
retinoid binding 1.91237853759594 bayes_pls_golite062009
vitamin D 24-hydroxylase activity 1.81919676974797 bayes_pls_golite062009
isoprenoid binding 1.78853880472253 bayes_pls_golite062009
vitamin D3 25-hydroxylase activity 1.65825585934141 bayes_pls_golite062009
vitamin D 25-hydroxylase activity 1.65825585934141 bayes_pls_golite062009
retinoic acid binding 1.55035199545719 bayes_pls_golite062009
electron carrier activity 1.48516712188486 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1.48367577297695 bayes_pls_golite062009
testosterone 6-beta-hydroxylase activity 1.4661447981611 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen 1.20113920678403 bayes_pls_golite062009
oxysterol 7-alpha-hydroxylase activity 1.13877300596184 bayes_pls_golite062009
binding 1.0881336564542 bayes_pls_golite062009
25-hydroxycholecalciferol-24-hydroxylase activity 1.06487564122685 bayes_pls_golite062009
demethylase activity 1.0502020132476 bayes_pls_golite062009
flavonoid 3'-monooxygenase activity 0.89030345144459 bayes_pls_golite062009
ecdysteroid 25-hydroxylase activity 0.89030345144459 bayes_pls_golite062009
catalytic activity 0.608111453189583 bayes_pls_golite062009
steroid 17-alpha-monooxygenase activity 0.56337818662492 bayes_pls_golite062009
sterol 14-demethylase activity 0.510328098559181 bayes_pls_golite062009
1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity 0.203772707673481 bayes_pls_golite062009
cholesterol monooxygenase (side-chain-cleaving) activity 0.100883462305119 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle