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View Structure Prediction Details

Protein: SWI5
Organism: Saccharomyces cerevisiae
Length: 709 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SWI5.

Description E-value Query
Range
Subject
Range
ZNF184 - zinc finger protein 184
gi|55626078, gi|... - gi|55626078|ref|XP_518298.1| PREDICTED: zinc finger protein 184 (Kruppel-like) isoform 5 [Pan troglo...
gi|167773647 - gi|167773647|gb|ABZ92258.1| zinc finger protein 184 [synthetic construct]
0.0 [93..708] [36..708]
gi|15929737, gi|... - gi|21703954|ref|NP_663458.1| zinc finger protein 160 [Mus musculus], gi|15929737|gb|AAH15291.1| Zinc...
0.0 [166..708] [5..604]
ZN252_CANLF - Zinc finger protein 252 OS=Canis lupus familiaris GN=ZNF252 PE=2 SV=1
0.0 [136..708] [222..830]

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Predicted Domain #1
Region A:
Residues: [1-74]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTSNSWFDA SKVQSLNFDL QTNSYYSNAR GSDPSSYAIE GEYKTLATDD LGNILNLNYG  60
   61 ETNEVIMNEI NDLN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.858 0.007 regulation of transcription involved in G1 phase of mitotic cell cycle d.95.1 Glucose permease domain IIB

Predicted Domain #2
Region A:
Residues: [75-182]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPLGPLSDEK SVKVSTFSEL IGNDWQSMNF DLENNSREVT LNATSLLNEN RLNQDSGMTV  60
   61 YQKTMSDKPH DEKKISMADN LLSTINKSEI NKGFDRNLGE LLLQQQQE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [183-298]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LREQLRAQQE ANKKLELELK QTQYKQQQLQ ATLENSDGPQ FLSPKRKISP ASENVEDVYA  60
   61 NSLSPMISPP MSNTSFTGSP SRRNNRQKYC LQRKNSSGTV GPLCFQELNE GFNDSL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
nucleic acid binding 2.36376512665406 bayes_pls_golite062009
DNA binding 2.2458683155586 bayes_pls_golite062009
binding 2.05464920186799 bayes_pls_golite062009
protein binding 0.476896736636797 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [299-359]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISPKKIRSNP NENLSSKTKF ITPFTPKSRV SSATSNSANI TPNNLRLDFK INVEDQESEY  60
   61 S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 1bbo__
Description: Enhancer binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [360-477]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKPLGLGIEL LGKPGPSPTK SVSLKSASVD IMPTIPGSVN NTPSVNKVSL SSSYIDQYTP  60
   61 RGKQLHFSSI SENALGINAA TPHLKPPSQQ ARHREGVFND LDPNVLTKNT DNEGDDNE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [478-584]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENEPESRFVI SETPSPVLKS QSKYEGRSPQ FGTHIKEINT YTTNSPSKIT RKLTTLPRGS  60
   61 IDKYVKEMPD KTFECLFPGC TKTFKRRYNI RSHIQTHLED RPYSCDH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 126.228787
Match: 2gliA_
Description: Five-finger GLI1
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [585-709]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGCDKAFVRN HDLIRHKKSH QEKAYACPCG KKFNREDALV VHRSRMICSG GKKYENVVIK  60
   61 RSPRKRGRPR KDGTSSVSSS PIKENINKDH NGQLMFKLED QLRRERSYDG NGTGIMVSPM 120
  121 KTNQR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 117.39794
Match: 1meyG_
Description: Designed zinc finger protein
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle