YRC Public Data Repository - Protein Structure Prediction

Protein:	RLI1
Organism:	Saccharomyces cerevisiae
Length:	608 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RLI1.

Description	E-value	Query Range	Subject Range
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[1..605]	[1..599]
gi\|7445550, gi\|7... - gi\|7657518\|ref\|NP_056566.1\| ATP-binding cassette, subfamily E, member 1 [Mus musculus], pir\|\|JC6555 ...	0.0	[1..605]	[1..599]
RLI1 - Essential iron-sulfur protein required for ribosome biogenesis and translation initiation; facilitat... gi\|151942081 - gi\|151942081\|gb\|EDN60437.1\| RNAse L inhibitor [Saccharomyces cerevisiae YJM789] gi\|190404942 - gi\|190404942\|gb\|EDV08209.1\| ATP-binding cassette sub-family E member 1 [Saccharomyces cerevisiae RM1... gi\|207346760 - gi\|207346760\|gb\|EDZ73159.1\| YDR091Cp-like protein [Saccharomyces cerevisiae AWRI1631] RLI1_YEAST - Translation initiation factor RLI1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RLI1 ...	0.0	[1..608]	[1..608]
gi\|16755057 - gi\|16755057\|gb\|AAL26702.1\| 68 kDa protein HP68 [Triticum aestivum]	0.0	[1..605]	[1..604]
gi\|987870, gi\|45... - gi\|987870\|emb\|CAA53972.1\| RNase L inhibitor [Homo sapiens], gi\|4506559\|ref\|NP_002931.1\| ATP-binding ...	0.0	[1..605]	[1..599]
AB1E_ARATH - ABC transporter E family member 1 OS=Arabidopsis thaliana GN=ABCE1 PE=2 SV=1	0.0	[1..605]	[1..603]
gi\|220948770 - gi\|220948770\|gb\|ACL86928.1\| pix-PA [synthetic construct] gi\|194118750, gi... - gi\|195326179\|ref\|XP_002029807.1\| GM24901 [Drosophila sechellia], gi\|194118750\|gb\|EDW40793.1\| GM24901... gi\|194196212, gi... - gi\|195588917\|ref\|XP_002084203.1\| GD12951 [Drosophila simulans], gi\|194196212\|gb\|EDX09788.1\| GD12951 ... gi\|190653363, gi... - gi\|194865740\|ref\|XP_001971580.1\| GG15047 [Drosophila erecta], gi\|190653363\|gb\|EDV50606.1\| GG15047 [D... pix-PA, pix-PB - The gene pixie is referred to in FlyBase by the symbol Dmel\pix (CG5651, FBgn0086706). It is a prote...	0.0	[2..605]	[10..607]
gi\|66803577, gi\|... - gi\|66803577\|ref\|XP_635627.1\| RNaseL inhibitor-like protein [Dictyostelium discoideum AX4], gi\|604639... gi\|60463939, gi\|... - gi\|60463939\|gb\|EAL62102.1\| RNaseL inhibitor-like protein [Dictyostelium discoideum], gi\|18874396\|gb\|...	0.0	[1..605]	[1..600]
gi\|18977042, gi\|... - gi\|18977042\|ref\|NP_578399.1\| putative ATPase RIL [Pyrococcus furiosus DSM 3638], gi\|18892677\|gb\|AAL8...	0.0	[6..603]	[1..589]
gi\|7445548 - pir\|\|G71136 probable transport protein - Pyrococcus horikoshii gi\|14590719, gi\|... - gi\|3257270\|dbj\|BAA29953.1\| 590aa long hypothetical transport protein [Pyrococcus horikoshii OT3], gi...	0.0	[6..604]	[1..590]

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Predicted Domain #1

Region A:
Residues: [1-73]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDKNSRIAI VSADKCKPKK CRQECKRSCP VVKTGKLCIE VTPTSKIAFI SEILCIGCGI  60
   61 CVKKCPFDAI QII

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	8.72
Match:	1kqfB
Description:	Formate dehydrogenase N, iron-sulfur (beta) subunit; Iron-sulfur subunit of formate dehydrogenase N, transmembrane anchor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.53159718897813	bayes_pls_golite062009
transporter activity	0.768779013335823	bayes_pls_golite062009
transmembrane transporter activity	0.519838051435455	bayes_pls_golite062009
catalytic activity	0.481338897251745	bayes_pls_golite062009
protein binding	0.247801183125276	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [74-367]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLPTNLEAHV THRYSANSFK LHRLPTPRPG QVLGLVGTNG IGKSTALKIL AGKQKPNLGR  60
   61 FDDPPEWQEI IKYFRGSELQ NYFTKMLEDD IKAIIKPQYV DNIPRAIKGP VQKVGELLKL 120
  121 RMEKSPEDVK RYIKILQLEN VLKRDIEKLS GGELQRFAIG MSCVQEADVY MFDEPSSYLD 180
  181 VKQRLNAAQI IRSLLAPTKY VICVEHDLSV LDYLSDFVCI IYGVPSVYGV VTLPASVREG 240
  241 INIFLDGHIP AENLRFRTEA LQFRIADATE DLQNDSASRA FSYPSLKKTQ GDFV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	179.9794
Match:	1g291_
Description:	Maltose transport protein MalK, C-terminal domain; Maltose transport protein MalK, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [368-608]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNVEEGEFSD SEILVMMGEN GTGKTTLIKL LAGALKPDEG QDIPKLNVSM KPQKIAPKFP  60
   61 GTVRQLFFKK IRGQFLNPQF QTDVVKPLRI DDIIDQEVQH LSGGELQRVA IVLALGIPAD 120
  121 IYLIDEPSAY LDSEQRIICS KVIRRFILHN KKTAFIVEHD FIMATYLADK VIVFEGIPSK 180
  181 NAHARAPESL LTGCNRFLKN LNVTFRRDPN SFRPRINKLD SQMDKEQKSS GNYFFLDNTG 240
  241 I

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	100.68867
Match:	1l7vC_
Description:	ABC transporter involved in vitamin B12 uptake, BtuD
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: