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View Structure Prediction Details

Protein: GIT1
Organism: Saccharomyces cerevisiae
Length: 518 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GIT1.

Description E-value Query
Range
Subject
Range
gi|151943909 - gi|151943909|gb|EDN62209.1| glycerophosphoinositol (GroPIns) permease [Saccharomyces cerevisiae YJM7...
GIT1 - Plasma membrane permease, mediates uptake of glycerophosphoinositol and glycerophosphocholine as sou...
GIT1_YEAST - Probable metabolite transport protein GIT1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) ...
1.0E-94 [1..518] [1..518]
gi|13676624 - gi|13676624|gb|AAK38197.1|AF305624_1 phosphate transporter 2 [Lupinus albus]
2.0E-89 [25..468] [2..520]
gi|8248034 - gi|8248034|gb|AAF74025.1|AF156696_1 inorganic phosphate transporter [Nicotiana tabacum]
6.0E-88 [25..480] [2..532]
gi|15983299 - gi|15983299|gb|AAL11542.1|AF416722_1 phosphate transporter [Oryza sativa subsp. indica]
8.0E-88 [28..468] [4..517]
gi|12697484 - gi|12697484|emb|CAC28218.1| phosphate transporter [Sesbania rostrata]
3.0E-87 [28..469] [4..521]
gi|17065936 - gi|17065936|emb|CAC87043.1| transmembrane protein [Solanum tuberosum]
9.0E-87 [25..468] [2..520]
PHT15_ARATH - Probable inorganic phosphate transporter 1-5 OS=Arabidopsis thaliana GN=PHT1-5 PE=2 SV=2
1.0E-86 [25..469] [2..522]

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Predicted Domain #1
Region A:
Residues: [1-518]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDKDITSVN EKEVNENTNP RIIKYDAERR ATRTETSKKD KWKNIVTIIA SGFALISDGY  60
   61 VNGSMSMLNK VFVMEYGKKN YSSKVSTRVS NAALVGIIFG QFFMGIAADY YSRKSCILVA 120
  121 TAILVIGSAL CAASHGTTVP GMFWMLTVMR GLVGIGVGAE YPTSTLSANE SANEYTTTKR 180
  181 GGILVMVTNL PLAFGGPFAT IIFLIVYKIC SGTKHLEAIW RTVFAIGCFW PLSVFYFRWK 240
  241 TATTEVYEKG RIKRNIPYFL ALKFYWKRLL GTCGTWFMYD FVTFPNGIFS STIISSVIKD 300
  301 QNDLVKVAEW NLLLGVLAVL GVPIGAYLSD RIGRKYTLMF GFSGYIIFGL IIGCAYDQLK 360
  361 KITPLFIIFY AFMNMLGNAG PGDMLGVISS EASATAVRGV FYGLSAVTGK IGSVVGVECF 420
  421 QPIRDNLGAR WTFIIAAICG LIGIIITYFF VPHSLESDLM KQDVEFHNYL VSNGWTGKMG 480
  481 FDETDEESMV RTIEVEENGT NCSKKNAEII SVRQVDQS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 75.30103
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

Predicted functions:

Term Confidence Notes
substrate-specific transmembrane transporter activity 5.21742729128468 bayes_pls_golite062009
ion transmembrane transporter activity 4.31748220369305 bayes_pls_golite062009
transporter activity 4.09176719149278 bayes_pls_golite062009
anion transmembrane transporter activity 3.74166040263114 bayes_pls_golite062009
cation transmembrane transporter activity 3.60627834007397 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transporter activity 3.3426261924492 bayes_pls_golite062009
organic anion transmembrane transporter activity 2.98462343619844 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 2.17838823008408 bayes_pls_golite062009
phosphate transmembrane transporter activity 1.78662033436109 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
binding 0.805286077372817 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
cation:sugar symporter activity 0.143419068761182 bayes_pls_golite062009
sugar:hydrogen symporter activity 0.143419068761182 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle