YRC Public Data Repository - Protein Structure Prediction

Protein:	YJ2I_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	316 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJ2I_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|118784226, gi... - gi\|118784226\|ref\|XP_313585.3\| ENSANGP00000013327 [Anopheles gambiae str. PEST], gi\|116128406\|gb\|EAA0...	294.0	[0..6]	[312..4]
Ppcs-PA - The gene Phosphopantothenoylcysteine synthetase is referred to in FlyBase by the symbol Dmel\Ppcs (C... gi\|220953596, gi... - gi\|220953596\|gb\|ACL89341.1\| CG5629-PA [synthetic construct], gi\|220943652\|gb\|ACL84369.1\| CG5629-PA [... gi\|195497857, gi... - gi\|195497857\|ref\|XP_002096278.1\| GE25151 [Drosophila yakuba], gi\|194182379\|gb\|EDW95990.1\| GE25151 [D... gi\|194198795, gi... - gi\|195569743\|ref\|XP_002102868.1\| GD20133 [Drosophila simulans], gi\|194198795\|gb\|EDX12371.1\| GD20133 ... gi\|194900038, gi... - gi\|194900038\|ref\|XP_001979564.1\| GG16174 [Drosophila erecta], gi\|190651267\|gb\|EDV48522.1\| GG16174 [D...	290.0	[0..4]	[311..1]
gi\|46129236, gi\|... - gi\|46129236\|ref\|XP_388979.1\| hypothetical protein FG08803.1 [Gibberella zeae PH-1], gi\|42549160\|gb\|E...	286.0	[0..3]	[315..11]
gi\|54637915, gi\|... - gi\|54637915\|gb\|EAL27317.1\| GA19016 [Drosophila pseudoobscura pseudoobscura], gi\|125773843\|ref\|XP_001... gi\|194101796, gi... - gi\|195143735\|ref\|XP_002012853.1\| GL23707 [Drosophila persimilis], gi\|194101796\|gb\|EDW23839.1\| GL2370... gi\|54637915\|gb\|E... - GA19016-PA [Drosophila pseudoobscura], GA19016 [Drosophila pseudoobscura pseudoobscura]	285.0	[0..4]	[309..1]
gi\|113623085, gi... - gi\|115475039\|ref\|NP_001061116.1\| Os08g0176100 [Oryza sativa (japonica cultivar-group)], gi\|113623085...	283.0	[0..5]	[311..10]
gi\|91094499 - gi\|91094499\|ref\|XP_971436.1\| PREDICTED: similar to CG5629 CG5629-PA [Tribolium castaneum]	282.0	[0..4]	[310..1]
PPCS - phosphopantothenoylcysteine synthetase	277.0	[0..1]	[309..1]

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Predicted Domain #1

Region A:
Residues: [1-316]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPEMDKSNDF FEENPCPNSL GDVSSLIEDF INLQSNSQNI AFVTSGGTLV PLEQNTVRFI  60
   61 DNFSAGNRGA ASAEYFCKSG YSVIFLYRNY SLMPFTRRYE GPWTNLFERS NGSQEKPWIV 120
  121 KQEFQSTVFN ALNELDTYTK HHRLIMIPYT TLTEYLWYLK AIAERLQIIA SRALFYLAAA 180
  181 VSDFHIPPKE LSEHKIQSGS GSNKLEVKMH PVPKFLRFLV DTWAPEASII SFKLETDPSI 240
  241 LIDKARVALQ RYNHQLVIAN LLSTRKRSVA FVTSKTVEWL HLSDDDIVKK VEIEQYIVSR 300
  301 AISLHKERIQ EFAKAP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	74.30103
Match:	1p9oA
Description:	Crystal Structure of Phosphopantothenoylcysteine Synthetase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphopantothenate--cysteine ligase activity	5.69075768451173	bayes_pls_golite062009
phosphopantothenoylcysteine decarboxylase activity	5.47152792211468	bayes_pls_golite062009
ligase activity	2.22669253992824	bayes_pls_golite062009
binding	1.89072001556053	bayes_pls_golite062009
acid-amino acid ligase activity	1.60765845284251	bayes_pls_golite062009
catalytic activity	1.32370671504792	bayes_pls_golite062009
carboxy-lyase activity	1.28899846789805	bayes_pls_golite062009
carbon-carbon lyase activity	0.53776941010038	bayes_pls_golite062009
protein binding	0.395135807048731	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.133284065682966	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: