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View Structure Prediction Details

Protein: gi|123994479, gi...
Organism: synthetic construct
Length: 508 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|123994479, gi....

Description E-value Query
Range
Subject
Range
gi|109123580 - gi|109123580|ref|XP_001110025.1| PREDICTED: phenylalanine-tRNA synthetase-like protein isoform 6 [Ma...
0.0 [1..508] [1..508]
gi|114675621 - gi|114675621|ref|XP_001170080.1| PREDICTED: hypothetical protein isoform 3 [Pan troglodytes]
0.0 [1..508] [1..508]
gi|60652859, gi|... - gi|60652859|gb|AAX29124.1| phenylalanine-tRNA synthetase-like alpha subunit [synthetic construct], g...
0.0 [1..508] [1..508]
SYFA_PONPY - Phenylalanyl-tRNA synthetase alpha chain - Pongo pygmaeus (Orangutan)
SYFA_PONAB - Phenylalanine--tRNA ligase alpha subunit OS=Pongo abelii GN=FARSA PE=2 SV=1
0.0 [1..508] [1..508]
gi|7804452 - gi|7804452|dbj|BAA95666.1| phenylalanyl tRNA synthetase beta subunit [Homo sapiens]
0.0 [1..508] [1..508]
SYFA_RAT - Phenylalanine--tRNA ligase alpha subunit OS=Rattus norvegicus GN=Farsa PE=1 SV=1
0.0 [1..508] [1..508]
gi|57101374 - gi|57101374|ref|XP_533900.1| PREDICTED: similar to Phenylalanyl-tRNA synthetase alpha chain (Phenyla...
0.0 [1..508] [1..508]

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Predicted Domain #1
Region A:
Residues: [1-117]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADGQVAELL LRRLEASDGG LDSAELAAEL GMEHQAVVGA VKSLQALGEV IEAELRSTKH  60
   61 WELTAEGEEI AREGSHEARV FRSIPPEGLA QSELMRLPSG KVGFSKAMSN KWIRVDK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.6
Match: 1p4xA
Description: Staphylococcal accessory regulator A homolog, SarS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.09413019441785 bayes_pls_golite062009
nucleic acid binding 2.8293727459515 bayes_pls_golite062009
DNA binding 2.66906990480864 bayes_pls_golite062009
binding 2.53822896550273 bayes_pls_golite062009
ligase activity 2.33035084655874 bayes_pls_golite062009
transcription factor activity 2.21460392371094 bayes_pls_golite062009
structural constituent of ribosome 0.764002516817766 bayes_pls_golite062009
structural molecule activity 0.756450227832198 bayes_pls_golite062009
sequence-specific DNA binding 0.665091289283954 bayes_pls_golite062009
protein binding 0.626618806841206 bayes_pls_golite062009
transcription activator activity 0.542530812773621 bayes_pls_golite062009
transcription repressor activity 0.423955395883599 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.0907538697485439 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [118-508]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SAADGPRVFR VVDSMEDEVQ RRLQLVRGGQ AEKLGEKERS ELRKRKLLAE VTLKTYWVSK  60
   61 GSAFSTSISK QETELSPEMI SSGSWRDRPF KPYNFLAHGV LPDSGHLHPL LKVRSQFRQI 120
  121 FLEMGFTEMP TDNFIESSFW NFDALFQPQQ HPARDQHDTF FLRDPAEALQ LPMDYVQRVK 180
  181 RTHSQGGYGS QGYKYNWKLD EARKNLLRTH TTSASARALY RLAQKKPFTP VKYFSIDRVF 240
  241 RNETLDATHL AEFHQIEGVV ADHGLTLGHL MGVLREFFTK LGITQLRFKP AYNPYTEPSM 300
  301 EVFSYHQGLK KWVEVGNSGV FRPEMLLPMG LPENVSVIAW GLSLERPTMI KYGINNIREL 360
  361 VGHKVNLQMV YDSPLCRLDA EPRPPPTQEA A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 78.0
Match: 1b70A
Description: Phenyl-tRNA synthetase (PheRS) alpha subunit, PheS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phenylalanine-tRNA ligase activity 13.8919118344182 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 12.5698315343202 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 12.5698315343202 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 12.5592545638101 bayes_pls_golite062009
ligase activity 6.92073480193262 bayes_pls_golite062009
glycine-tRNA ligase activity 2.61548498770105 bayes_pls_golite062009
threonine-tRNA ligase activity 2.18642354927 bayes_pls_golite062009
serine-tRNA ligase activity 2.07594942154162 bayes_pls_golite062009
catalytic activity 1.99372273395202 bayes_pls_golite062009
alanine-tRNA ligase activity 1.82594054955281 bayes_pls_golite062009
lysine-tRNA ligase activity 1.72324031407565 bayes_pls_golite062009
histidine-tRNA ligase activity 1.72215103383322 bayes_pls_golite062009
asparagine-tRNA ligase activity 0.921492123574877 bayes_pls_golite062009
binding 0.705666054154871 bayes_pls_golite062009
aspartate-tRNA ligase activity 0.00572514744734753 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle