YRC Public Data Repository - Protein Structure Prediction

Protein:	APS1_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	210 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for APS1_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|42781140, gi\|... - gi\|42781140\|ref\|NP_978387.1\| mutT/nudix family protein [Bacillus cereus ATCC 10987], gi\|42737061\|gb\|...	116.0	[0..10]	[168..70]
gi\|228844935, gi... - gi\|228914616\|ref\|ZP_04078225.1\| MutT/nudix [Bacillus thuringiensis serovar pulsiensis BGSC 4CC1], gi... gi\|228859035, gi... - gi\|228900616\|ref\|ZP_04064837.1\| MutT/nudix [Bacillus thuringiensis IBL 4222], gi\|228859035\|gb\|EEN034... gi\|74492958, gi\|... - gi\|75759527\|ref\|ZP_00739616.1\| Phosphohydrolase (MutT/nudix family protein) [Bacillus thuringiensis ... gi\|228933324, gi... - gi\|228933324\|ref\|ZP_04096180.1\| MutT/nudix [Bacillus thuringiensis serovar andalousiensis BGSC 4AW1]... gi\|228832595, gi... - gi\|228927088\|ref\|ZP_04090153.1\| MutT/nudix [Bacillus thuringiensis serovar pondicheriensis BGSC 4BA1... gi\|228662037, gi... - gi\|229121573\|ref\|ZP_04250800.1\| MutT/nudix [Bacillus cereus 95/8201], gi\|228662037\|gb\|EEL17650.1\| Mu... gi\|228965012, gi... - gi\|228965012\|ref\|ZP_04126112.1\| MutT/nudix [Bacillus thuringiensis serovar sotto str. T04001], gi\|22...	115.0	[0..11]	[168..1]
gi\|190407482 - gi\|190407482\|gb\|EDV10749.1\| diadenosine and diphosphoinositol polyphosphate phosphohydrolase [Saccha... gi\|151945782 - gi\|151945782\|gb\|EDN64023.1\| diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase [Saccharomyces cerevi... DDP1_YEAST - Diphosphoinositol polyphosphate phosphohydrolase DDP1 OS=Saccharomyces cerevisiae (strain ATCC 20450... DDP1 - Polyphosphate phosphatase; hydrolyzes diphosphorylated inositol polyphosphates and diadenosine polyp...	114.0	[0..21]	[209..11]
gi\|49178793, gi\|... - gi\|49184866\|ref\|YP_028118.1\| mutT/nudix family protein [Bacillus anthracis str. Sterne], gi\|49178793... gi\|47502442, gi\|... - gi\|47527294\|ref\|YP_018643.1\| mutT/nudix family protein [Bacillus anthracis str. 'Ames Ancestor'], gi... gi\|30256651, gi\|... - gi\|30262025\|ref\|NP_844402.1\| mutT/nudix family protein [Bacillus anthracis str. Ames], gi\|30256651\|g... gi\|227815180, gi... - gi\|227815180\|ref\|YP_002815189.1\| mutT/nudix family protein [Bacillus anthracis str. CDC 684], gi\|227... gi\|21399872, gi\|... - gi\|65319308\|ref\|ZP_00392267.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ... gi\|229602087, gi... - gi\|229602087\|ref\|YP_002866391.1\| MutT/NUDIX family protein [Bacillus anthracis str. A0248], gi\|22926... gi\|254684590 - gi\|254684590\|ref\|ZP_05148450.1\| mutT/nudix family protein [Bacillus anthracis str. CNEVA-9066] gi\|254721348 - gi\|254721348\|ref\|ZP_05183138.1\| mutT/nudix family protein [Bacillus anthracis str. A1055] gi\|254734896 - gi\|254734896\|ref\|ZP_05192608.1\| mutT/nudix family protein [Bacillus anthracis str. Western North Ame... gi\|254741295 - gi\|254741295\|ref\|ZP_05198983.1\| mutT/nudix family protein [Bacillus anthracis str. Kruger B] gi\|254750847 - gi\|254750847\|ref\|ZP_05202886.1\| mutT/nudix family protein [Bacillus anthracis str. Vollum] gi\|254760087 - gi\|254760087\|ref\|ZP_05212111.1\| mutT/nudix family protein [Bacillus anthracis str. Australia 94] gi\|167531854, gi... - gi\|167633042\|ref\|ZP_02391368.1\| mutT/nudix family protein [Bacillus anthracis str. A0442], gi\|167531... gi\|165870172, gi... - gi\|165870172\|ref\|ZP_02214828.1\| mutT/nudix family protein [Bacillus anthracis str. A0488], gi\|164714... gi\|170686357, gi... - gi\|170686357\|ref\|ZP_02877578.1\| mutT/nudix family protein [Bacillus anthracis str. A0465], gi\|170669... gi\|167513597, gi... - gi\|167638296\|ref\|ZP_02396573.1\| mutT/nudix family protein [Bacillus anthracis str. A0193], gi\|167513... gi\|177650916, gi... - gi\|177650916\|ref\|ZP_02933813.1\| mutT/nudix family protein [Bacillus anthracis str. A0174], gi\|172083... gi\|170128966, gi... - gi\|170705964\|ref\|ZP_02896426.1\| mutT/nudix family protein [Bacillus anthracis str. A0389], gi\|170128... gi\|190559709, gi... - gi\|190569208\|ref\|ZP_03022105.1\| mutT/nudix family protein [Bacillus anthracis Tsiankovskii-I], gi\|19...	113.0	[0..19]	[168..3]
gi\|228599347, gi... - gi\|229184232\|ref\|ZP_04311441.1\| MutT/nudix [Bacillus cereus BGSC 6E1], gi\|228599347\|gb\|EEK56958.1\| M... gi\|225863955, gi... - gi\|225863955\|ref\|YP_002749333.1\| mutT/nudix family protein [Bacillus cereus 03BB102], gi\|225790495\|g... gi\|52143428, gi\|... - gi\|52143428\|ref\|YP_083404.1\| MutT/Nudix family protein [Bacillus cereus E33L], gi\|51976897\|gb\|AAU184... gi\|218896980, gi... - gi\|218896980\|ref\|YP_002445391.1\| mutT/nudix family protein [Bacillus cereus G9842], gi\|218542576\|gb\|... gi\|196047289, gi... - gi\|196047289\|ref\|ZP_03114504.1\| mutT/nudix family protein [Bacillus cereus 03BB108], gi\|196021914\|gb... gi\|196039751, gi... - gi\|196039751\|ref\|ZP_03107055.1\| mutT/nudix family protein [Bacillus cereus NVH0597-99], gi\|196029454...	113.0	[0..19]	[168..3]
gi\|218903146, gi... - gi\|218903146\|ref\|YP_002450980.1\| mutT/nudix family protein [Bacillus cereus AH820], gi\|218538674\|gb\|... gi\|195990582, gi... - gi\|196036779\|ref\|ZP_03104169.1\| mutT/nudix family protein [Bacillus cereus W], gi\|195990582\|gb\|EDX54... gi\|49333329, gi\|... - gi\|49481773\|ref\|YP_036157.1\| MutT/Nudix family protein [Bacillus thuringiensis serovar konkukian str...	112.0	[0..19]	[168..3]
gi\|229079201, gi... - gi\|229079201\|ref\|ZP_04211749.1\| MutT/nudix [Bacillus cereus Rock4-2], gi\|228704127\|gb\|EEL56565.1\| Mu... gi\|30020131, gi\|... - gi\|30020131\|ref\|NP_831762.1\| phosphohydrolase (MutT/nudix family protein) [Bacillus cereus ATCC 1457... gi\|229178427, gi... - gi\|229178427\|ref\|ZP_04305795.1\| MutT/nudix [Bacillus cereus 172560W], gi\|228605065\|gb\|EEK62518.1\| Mu... gi\|229150256, gi... - gi\|229150256\|ref\|ZP_04278477.1\| MutT/nudix [Bacillus cereus m1550], gi\|228633228\|gb\|EEK89836.1\| MutT... gi\|218232561, gi... - gi\|218232561\|ref\|YP_002366716.1\| mutT/nudix family protein [Bacillus cereus B4264], gi\|218160518\|gb\|...	110.0	[0..19]	[168..3]
gi\|238882621 - gi\|238882621\|gb\|EEQ46259.1\| diphosphoinositol polyphosphate phosphohydrolase DDP1 [Candida albicans ... gi\|46442546, gi\|... - gi\|68470587\|ref\|XP_720539.1\| hypothetical protein CaO19.4229 [Candida albicans SC5314], gi\|68470324\|... orf19.4229, orf1... - orf19.4229 CGDID:CAL0000145 Assembly 19, Contig19-10202 (18312, 17734) CDS, reverse complemented, tr...	108.0	[0..21]	[208..14]
gi\|19915297, gi\|... - gi\|20090298\|ref\|NP_616373.1\| NAD+ pyrophosphatase [Methanosarcina acetivorans C2A], gi\|19915297\|gb\|A...	108.0	[0..5]	[175..112]
gi\|49645126 - gi\|49645126\|emb\|CAG98698.1\| KLLA0F20273p [Kluyveromyces lactis] gi\|50311917, gi\|... - gi\|50311917\|ref\|XP_455990.1\| unnamed protein product [Kluyveromyces lactis], gi\|49645126\|emb\|CAG9869...	107.0	[0..19]	[207..3]

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Predicted Domain #1

Region A:
Residues: [1-210]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLENNGSVIL MEPDHLRTAV NRSMTSREGR TKNRFNPITG ARLAAGVVAL SADKRKVLLV  60
   61 SSAKKHPSWV VPKGGWEADE SVQQAALREG WEEGGLVGHI TRSLGSFKDK RPTDTIDRRK 120
  121 KYLKQLMSKS SGNDVSTNTE LGAEAEKLLL PPRAECEFFE VIVERLEDNY PEMRKRRRKW 180
  181 MSYQEAKEAL TSRKDILAAL EKSSIIKEEN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.522879
Match:	1u20A
Description:	Crystal Structure of Xenopus laevis nudix hydrolase nuclear SnoRNA decapping Protein X29
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.49075808737475	bayes_pls_golite062009
hydrolase activity	1.08437985755037	bayes_pls_golite062009
nucleic acid binding	0.654571025500586	bayes_pls_golite062009
binding	0.648929968265004	bayes_pls_golite062009
transferase activity	0.338414890259504	bayes_pls_golite062009
protein binding	0.0607475466763231	bayes_pls_golite062009
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity	0.0140979802606357	bayes_pls_golite062009
bis(5'-nucleosyl)-tetraphosphatase activity	0.0140979802606357	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: