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Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = 2 NDP. Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments. Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate. Catalysis of the hydrolysis of P(1),P(4)-bis(5'-nucleosyl)tetraphosphate into two nucleotides. Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: bis(5'-nucleosyl)-tetraphosphatase activity
Acc: GO:0008796
Aspect: Molecular Function
Desc: Catalysis of the hydrolysis of P(1),P(4)-bis(5'-nucleosyl)tetraphosphate into two nucleotides.
Proteins in PDR annotated with:
   This term: 4 [Search]
   Term or descendants: 34 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008796 - bis(5'-nucleosyl)-tetraphosphatase activity (interactive image map)
YRC Informatics Platform - Version 3.0
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