| Protein: | ggr-2 |
| Organism: | Caenorhabditis elegans |
| Length: | 546 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ggr-2.
| Description | E-value | Query Range |
Subject Range |
|
|
348.0 | [0..11] | [542..82] |
|
Region A: Residues: [1-343] |
1 11 21 31 41 51
| | | | | |
1 MLLVSSIFLL LYRNSPKVEA SRSEPVPIYL DNLLNAGRQV YDNQSPPVQH DKEEVTVVEL 60
61 AMYIEGMSSF RTQTMDFQLD VYFQQFWRDP RLAHNETRRV LVKDKAVLHK MWKPDVYFAN 120
121 ARIAEFHEVT QPNFLVWIQP DGSILYDTRI SMVVVCTLNL EKWPLDSQRC HLRILSYAYT 180
181 TEQLVIKWKE DEPITRNPNI AMSDMHIVDL YPGLCDGNYS TGTWSCVTAE FFVKREITHH 240
241 VMQSYVPTTL IVVISWFSFW LDVEAVPARV SLAITTLLTL STQANAARMA LPEVSYMKAI 300
301 DVWMGACMMF VFGVMIEFTI VNYAQRQGRK WHRTDAEIVM ASS
|
| Detection Method: |  |
| Confidence: | 69.30103 |
| Match: | 2bg9A |
| Description: | Refined structure of the nicotinic acetylcholine receptor at 4A resolution. |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [344-463] |
1 11 21 31 41 51
| | | | | |
1 LESVKSGNAE KKPSRGDLGA HARHLFLRLR TNERQHLVED PPEQIAMNDT AYDTVSQAYS 60
61 NSFSDEEAAP VVQPPQNEDA EAQEEVWAEQ KETNLSEVWK ESDPAERLAH WNEKENDASS 120
121
|
| Detection Method: | |
| Confidence: | 24.221849 |
| Match: | 1oedC |
| Description: | Acetylcholine receptor protein, delta chain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| ion transmembrane transporter activity | 7.22265353460749 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 7.15153709132033 | bayes_pls_golite062009 |
| channel activity | 7.15153709132033 | bayes_pls_golite062009 |
| ion channel activity | 7.1489450300492 | bayes_pls_golite062009 |
| gated channel activity | 7.07040350691167 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 7.06843378380114 | bayes_pls_golite062009 |
| cation channel activity | 7.05528966701307 | bayes_pls_golite062009 |
| substrate-specific channel activity | 7.02602175506525 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 6.7875346065164 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 6.75385972663331 | bayes_pls_golite062009 |
| nicotinic acetylcholine-activated cation-selective channel activity | 6.68325610876107 | bayes_pls_golite062009 |
| ligand-gated channel activity | 6.54466087904138 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 6.54466087904138 | bayes_pls_golite062009 |
| neurotransmitter binding | 6.11782125343012 | bayes_pls_golite062009 |
| neurotransmitter receptor activity | 5.97698567435878 | bayes_pls_golite062009 |
| extracellular ligand-gated ion channel activity | 5.96773594514842 | bayes_pls_golite062009 |
| excitatory extracellular ligand-gated ion channel activity | 5.96773594514842 | bayes_pls_golite062009 |
| acetylcholine binding | 5.82006373570659 | bayes_pls_golite062009 |
| acetylcholine receptor activity | 5.72083104614502 | bayes_pls_golite062009 |
| transmembrane receptor activity | 5.4080353535498 | bayes_pls_golite062009 |
| receptor activity | 5.11329651194787 | bayes_pls_golite062009 |
| transporter activity | 5.11262082564788 | bayes_pls_golite062009 |
| transmembrane transporter activity | 5.03439798256257 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 4.91314874981447 | bayes_pls_golite062009 |
| molecular transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| signal transducer activity | 4.12549692767753 | bayes_pls_golite062009 |
| amine binding | 3.99316633473025 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 3.09231388867595 | bayes_pls_golite062009 |
| chloride channel regulator activity | 2.30670892326006 | bayes_pls_golite062009 |
| binding | 2.2810963754869 | bayes_pls_golite062009 |
| G-protein coupled amine receptor activity | 1.37431949258757 | bayes_pls_golite062009 |
| 1.15330735898282 | bayes_pls_golite062009 | |
| channel regulator activity | 1.13923307634251 | bayes_pls_golite062009 |
| beta-amyloid binding | 1.10082189665627 | bayes_pls_golite062009 |
| toxin binding | 0.91098263903324 | bayes_pls_golite062009 |
| protein binding | 0.406954670483187 | bayes_pls_golite062009 |
| drug binding | 0.1024174756655 | bayes_pls_golite062009 |
| serotonin receptor activity | 0.0879353619248899 | bayes_pls_golite062009 |
|
Region A: Residues: [464-546] |
1 11 21 31 41 51
| | | | | |
1 PLMGNGRAHV RYGAAEKMKN RKCNDSSRKK EKWSSAIKQI QKHKKIAGRN RAKKIDQTSR 60
61 WIFPLTFIIF NLTYWIYYLY WKE
|
| Detection Method: | |
| Confidence: | 1.38 |
| Match: | 1oedC |
| Description: | Acetylcholine receptor protein, delta chain |
| Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| ion transmembrane transporter activity | 6.77040948038207 | bayes_pls_golite062009 |
| passive transmembrane transporter activity | 6.54632954876879 | bayes_pls_golite062009 |
| channel activity | 6.54632954876879 | bayes_pls_golite062009 |
| ion channel activity | 6.54081091818708 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 6.53282135350974 | bayes_pls_golite062009 |
| gated channel activity | 6.45068814746887 | bayes_pls_golite062009 |
| cation channel activity | 6.44482558831924 | bayes_pls_golite062009 |
| substrate-specific channel activity | 6.43078004966793 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 6.36378031146392 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 6.29833803742064 | bayes_pls_golite062009 |
| nicotinic acetylcholine-activated cation-selective channel activity | 5.96791824940609 | bayes_pls_golite062009 |
| ligand-gated channel activity | 5.87382805697746 | bayes_pls_golite062009 |
| ligand-gated ion channel activity | 5.87382805697746 | bayes_pls_golite062009 |
| neurotransmitter binding | 5.54157394911009 | bayes_pls_golite062009 |
| neurotransmitter receptor activity | 5.41758713081321 | bayes_pls_golite062009 |
| excitatory extracellular ligand-gated ion channel activity | 5.240450320112 | bayes_pls_golite062009 |
| extracellular ligand-gated ion channel activity | 5.240450320112 | bayes_pls_golite062009 |
| acetylcholine binding | 5.15331199329751 | bayes_pls_golite062009 |
| acetylcholine receptor activity | 5.06338031097833 | bayes_pls_golite062009 |
| transmembrane receptor activity | 5.04630162986246 | bayes_pls_golite062009 |
| receptor activity | 4.78457368651236 | bayes_pls_golite062009 |
| transporter activity | 4.73973512233464 | bayes_pls_golite062009 |
| transmembrane transporter activity | 4.64706802893702 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 4.51057101522234 | bayes_pls_golite062009 |
| signal transducer activity | 3.87903570844696 | bayes_pls_golite062009 |
| molecular transducer activity | 3.87903570844696 | bayes_pls_golite062009 |
| amine binding | 3.42320290513776 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 3.02725446389008 | bayes_pls_golite062009 |
| binding | 2.18972894667097 | bayes_pls_golite062009 |
| chloride channel regulator activity | 1.74675124590896 | bayes_pls_golite062009 |
| G-protein coupled amine receptor activity | 1.12733413163727 | bayes_pls_golite062009 |
| 0.859417963545377 | bayes_pls_golite062009 | |
| channel regulator activity | 0.842700523410834 | bayes_pls_golite062009 |
| beta-amyloid binding | 0.704684393278994 | bayes_pls_golite062009 |
| toxin binding | 0.48890633184828 | bayes_pls_golite062009 |
| protein binding | 0.414375631224425 | bayes_pls_golite062009 |
