YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|11258290
Organism:	Vibrio cholerae
Length:	177 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|11258290.

Description	E-value	Query Range	Subject Range
TILS_LISIN - Bifunctional protein TilS/HprT OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=tilS/hprT PE=3 ... TILS_LISIN - Bifunctional protein tilS/hprT OS=Listeria innocua GN=tilS/hprT PE=3 SV=1	157.0	[0..2]	[175..472]
gi\|224500330 - gi\|224500330\|ref\|ZP_03668679.1\| hypothetical protein LmonF1_11939 [Listeria monocytogenes Finland 19... gi\|224503461 - gi\|224503461\|ref\|ZP_03671768.1\| hypothetical protein LmonFR_13287 [Listeria monocytogenes FSL R2-561... gi\|126941298, gi... - gi\|254900996\|ref\|ZP_05260920.1\| hypothetical protein LmonJ_14318 [Listeria monocytogenes J0161], gi\|... gi\|254913936, gi... - gi\|254913936\|ref\|ZP_05263948.1\| hypothetical protein LmonJ2_14108 [Listeria monocytogenes J2818], gi... gi\|133733948, gi... - gi\|254938274\|ref\|ZP_05269971.1\| hypothetical protein LmonF6_14141 [Listeria monocytogenes F6900], gi... gi\|47014358, gi\|... - gi\|47097258\|ref\|ZP_00234818.1\| conserved hypothetical protein/hypoxanthine phosphoribosyltransferase... TILS_LISMO - Bifunctional protein TilS/HprT OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) ... TILS_LISMO - Bifunctional protein tilS/hprT OS=Listeria monocytogenes GN=tilS/hprT PE=3 SV=1	157.0	[0..2]	[175..472]
TILS_LISMF - Bifunctional protein TilS/HprT OS=Listeria monocytogenes serotype 4b (strain F2365) GN=tilS/hprT PE=...	157.0	[0..2]	[175..472]
gi\|226222848, gi... - gi\|226222848\|ref\|YP_002756955.1\| hypothetical protein Lm4b_00217 [Listeria monocytogenes Clip81459],... gi\|47018468, gi\|... - gi\|47093161\|ref\|ZP_00230936.1\| conserved hypothetical protein/hypoxanthine phosphoribosyltransferase... gi\|21667249 - gi\|21667249\|gb\|AAM74001.1\|AF467001_2 YacA/HprT-like protein [Listeria monocytogenes] gi\|153200654, gi... - gi\|254933059\|ref\|ZP_05266418.1\| hypothetical protein LmonH_11532 [Listeria monocytogenes HPB2262], g...	156.0	[0..2]	[175..472]
gi\|54310268, gi\|... - gi\|54310268\|ref\|YP_131288.1\| hypoxanthine-guanine phosphoribosyltransferase [Photobacterium profundu...	156.0	[0..1]	[177..22]
gi\|90412013, gi\|... - gi\|90412013\|ref\|ZP_01220020.1\| hypoxanthine-guanine phosphoribosyltransferase [Photobacterium profun...	156.0	[0..1]	[177..1]
gi\|197334569, gi... - gi\|197334569\|ref\|YP_002156974.1\| hypoxanthine phosphoribosyltransferase [Vibrio fischeri MJ11], gi\|1... gi\|59480884, gi\|... - gi\|59712783\|ref\|YP_205559.1\| hypoxanthine phosphoribosyltransferase [Vibrio fischeri ES114], gi\|5948...	156.0	[0..1]	[176..1]
gi\|218323518, gi... - gi\|218710499\|ref\|YP_002418120.1\| Hypoxanthine phosphoribosyltransferase [Vibrio splendidus LGP32], g... gi\|85833920, gi\|... - gi\|86148295\|ref\|ZP_01066590.1\| hypoxanthine-guanine phosphoribosyltransferase [Vibrio sp. MED222], g...	155.0	[0..1]	[176..1]
gi\|194534313, gi... - gi\|75821894\|ref\|ZP_00751642.1\| COG0634: Hypoxanthine-guanine phosphoribosyltransferase [Vibrio chole... tr\|A0A085TAP4\|A0... - Hypoxanthine phosphoribosyltransferase OS=Vibrio cholerae GN=hpt PE=4 SV=1, Hypoxanthine phosphoribo...	153.0	[0..1]	[177..1]
gi\|28899289, gi\|... - gi\|28899289\|ref\|NP_798894.1\| hypoxanthine-guanine phosphoribosyltransferase [Vibrio parahaemolyticus... gi\|28807513, gi\|... - gi\|28807513\|dbj\|BAC60778.1\| hypoxanthine ribosyl transferase [Vibrio parahaemolyticus RIMD 2210633],...	153.0	[0..1]	[176..1]

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Predicted Domain #1

Region A:
Residues: [1-177]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKHTVEVMIS EQEVAQRIRE LGQQITEHYQ GSSDLVLVGL LRGSFVFMAD LARQIHLTHQ  60
   61 VDFMTASSYG NSMQSSRDVR ILKDLDDDIK GKDVLLVEDI IDTGNTLNKV KEILALREPK 120
  121 SIRICTLLDK PTRREVDVEV NWVGFEIPDE FVVGVGIDYA QKYRHLPYIG KVVPLAE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.39794
Match:	1j7jA
Description:	Hypoxanthine PRTase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
adenine phosphoribosyltransferase activity	4.07252508868782	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	3.91023158228049	bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity	3.89356447922614	bayes_pls_golite062009
transferase activity	2.73727660668741	bayes_pls_golite062009
nucleobase binding	2.70671399975507	bayes_pls_golite062009
purine binding	2.63033967717893	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.53679639481311	bayes_pls_golite062009
uracil phosphoribosyltransferase activity	2.36237864658341	bayes_pls_golite062009
catalytic activity	2.30431811394775	bayes_pls_golite062009
amidophosphoribosyltransferase activity	1.6596316647688	bayes_pls_golite062009
ribose phosphate diphosphokinase activity	1.51875493459374	bayes_pls_golite062009
protein binding	1.02514711359042	bayes_pls_golite062009
adenine binding	0.817887117933035	bayes_pls_golite062009
diphosphotransferase activity	0.749909396904601	bayes_pls_golite062009
binding	0.644392905117932	bayes_pls_golite062009
nucleic acid binding	0.439453264070391	bayes_pls_golite062009
transcription regulator activity	0.369893745269311	bayes_pls_golite062009
DNA binding	0.275043319532312	bayes_pls_golite062009
orotate phosphoribosyltransferase activity	0.148898393751978	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: